Original Research

Accepted on 09 Jan 2025

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

in Molecular Diagnostics and Therapeutics

Chunjiang Tan
Juan Wang
Xiangrong Ye
Kaidirina Kasimu
Ye Li
Feng Luo
Hui Yi
Yifeng Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1507163

Original Research

Accepted on 09 Jan 2025

Immune Cells in Thyroid Adenoma and Carcinoma: Uncovering a Hidden Value of Assessing Tumor-Host Interplay and its Potential Application in Thyroid Cytopathology

in Molecular Diagnostics and Therapeutics

Iryna Omelianenko
Nazarii Kobyliak
Tetyana Falalyeyeva
Oleksii Seleznov
Pavlina Botsun
Lyudmila Ostapchenko
Oleksandr Korotkyi
Liudmyla Domylivska
Olena Tsyryuk
Galyna Mykhalchyshyn

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542821

Original Research

Published on 09 Jan 2025

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

in Molecular Diagnostics and Therapeutics

Yan Zhang
Xiujuan Chen
Yuan Lin
Xiaoqing Liu
Xiumei Xiong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1504015

180 views

Mini Review

Published on 08 Jan 2025

Artificial molecular motors in biological applications

in Molecular Diagnostics and Therapeutics

Fuli Fan
Songshen Liu
Yuting Yan
Peng Zhang
Kui Che

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1510619

138 views

Editorial

Accepted on 07 Jan 2025

Oncolytic Virotherapy II

in Molecular Diagnostics and Therapeutics

Ahmed Majeed Al-Shammari
Pier Paolo Piccaluga

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1552643

143 views

Original Research

Accepted on 07 Jan 2025

Homologous Recombination Deficiency (HRD) Test Validation for Patients with High-Grade Advanced Ovarian Cancer

in Molecular Diagnostics and Therapeutics

Angelica Nogueira Rodrigues
Andreza Karine de Barros Almeida Souto
Diocésio Alves Pinto de Andrade
Larissa Müller Gomes
Sandra Satie Koide
Renata de Godoy e Silva
Bruno Batista de Souza
Juliana Doblas Massaro
Andréia Cristina de Melo
Andrea Morais Borges

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1524594

Editorial

Published on 07 Jan 2025

Editorial: Modelling esophageal adenocarcinoma

in Molecular Diagnostics and Therapeutics

Hisham F. Bahmad
Farah Ballout

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1550595

196 views

Original Research

Published on 07 Jan 2025

Exploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysis

in Molecular Diagnostics and Therapeutics

Xiaofang Liu
Bin Li
Yuxi Lin
Xueying Ma
Yingying Liu
Lili Ma
Xiaomeng Ma
Xia Wang
Nanjing Li
Xiaoyun Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1520050

204 views

Original Research

Accepted on 06 Jan 2025

Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis

in Molecular Diagnostics and Therapeutics

Qingchang Tian
Xiao Du
Hongxiu Li
Shiyi Shen
Chao Tian
Xiaohuan Cao
Xingang Xu
Nan Xu
Wang Shuling

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1531108

Original Research

Accepted on 06 Jan 2025

A CRISPR-Cas-based Recombinase Polymerase Amplification (RPA) Assay for Ultra-Sensitive Detection of Active Trypanosoma brucei evansi Infections

in Molecular Diagnostics and Therapeutics

Andrés Álvarez-Rodríguez
Zeng Li
Bo-Kyung Jin
Benoit Stijlemans
Peter Geldhof
Stefan Magez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1512970

Original Research

Published on 06 Jan 2025

Identification and validation of five ferroptosis-related molecular signatures in keloids based on multiple transcriptome data analysis

in Molecular Diagnostics and Therapeutics

Zhen Sun
Yonghong Qin
Xuanfen Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1490745

230 views

Original Research

Published on 06 Jan 2025

Identification and validation of reference genes for quantitative gene expression analysis under 409 and 415 nm antimicrobial blue light treatment

in Molecular Diagnostics and Therapeutics

Beata Kruszewska-Naczk
Mariusz Grinholc
Aleksandra Rapacka-Zdonczyk

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1467726

233 views

Original Research

Accepted on 03 Jan 2025

Application of Bioinformatics-Based CDK1 and STAT1 in the Diagnosis of Acute Kidney Injury in Patients with Gastrointestinal Cancers

in Molecular Diagnostics and Therapeutics

Qiuwan Wei
Yiqing Shen
Yiren Tian
Yunzhi Ling

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1522246

Review

Published on 03 Jan 2025

LncRNA HOXA10-AS as a novel biomarker and therapeutic target in human cancers

in Molecular Diagnostics and Therapeutics

Xin Hu
Yong Wang
Sijia Zhang
Xiaosi Gu
Xiaoyu Zhang
Lianlian Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1520498

221 views

Original Research

Published on 03 Jan 2025

Unveiling and validating biomarkers related to the IL-10 family in chronic sinusitis with nasal polyps: insights from transcriptomics and single-cell RNA sequencing analysis

in Molecular Diagnostics and Therapeutics

Xinghong Liu
Yi Peng
Ling Guo
Weilan Xiong
Weijiang Liao
Jiangang Fan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1513951

201 views

Original Research

Accepted on 02 Jan 2025

Global Trends and Emerging Insights in BRAF and MEK Inhibitor Resistance in Melanoma: A Bibliometric Analysis

in Molecular Diagnostics and Therapeutics

Jianhao Bai
Zhongqi Wan
Wanru Zhou
Lijun Wang
Wei Lou
Yao Zhang
Haiying Jin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538743

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Articles

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

Immune Cells in Thyroid Adenoma and Carcinoma: Uncovering a Hidden Value of Assessing Tumor-Host Interplay and its Potential Application in Thyroid Cytopathology

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

Artificial molecular motors in biological applications

Oncolytic Virotherapy II

Homologous Recombination Deficiency (HRD) Test Validation for Patients with High-Grade Advanced Ovarian Cancer

Editorial: Modelling esophageal adenocarcinoma

Exploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysis

Labeling tumor-associated extracellular vesicles with antibody-DNA conjugates for quantitative analysis

A CRISPR-Cas-based Recombinase Polymerase Amplification (RPA) Assay for Ultra-Sensitive Detection of Active Trypanosoma brucei evansi Infections

Identification and validation of five ferroptosis-related molecular signatures in keloids based on multiple transcriptome data analysis

Identification and validation of reference genes for quantitative gene expression analysis under 409 and 415 nm antimicrobial blue light treatment

Application of Bioinformatics-Based CDK1 and STAT1 in the Diagnosis of Acute Kidney Injury in Patients with Gastrointestinal Cancers

LncRNA HOXA10-AS as a novel biomarker and therapeutic target in human cancers

Unveiling and validating biomarkers related to the IL-10 family in chronic sinusitis with nasal polyps: insights from transcriptomics and single-cell RNA sequencing analysis

Global Trends and Emerging Insights in BRAF and MEK Inhibitor Resistance in Melanoma: A Bibliometric Analysis