Frontiers in Medical Technology | Pharmaceutical Innovation

Original Research

Accepted on 15 Jan 2025

Bioanalytical Method development, in-vivo pharmacokinetic evaluation, exvivo platelet aggregation inhibition activity of a novel solid dispersion formulation of Ticagrelor

in Pharmaceutical Innovation

Abhishek Srivastava
Simrata Bedi
Abhishesh Kumar Mehata
Datta Maroti Pawde
Ketan Vinayakrao Hatware
Mohammad Ahmad Khan
M.S. Muthu
Uma Bhandari

Frontiers in Medical Technology

doi 10.3389/fmedt.2025.1499189

Review

Published on 21 Nov 2024

Cost-effective track and trace technology for poor-quality chemotherapeutic pharmaceuticals in resource-limited countries: a review of the Chemotherapeutic Paper Analytical Device

in Pharmaceutical Innovation

Minichil Chanie Worku
Liknew Workie Limenh
Biset Asrade Mekonnen
Yeniewa Kerie Anagaw

Frontiers in Medical Technology

doi 10.3389/fmedt.2024.1436614

532 views

Review

Published on 23 Jan 2024

The use of nanoparticles in the treatment of infectious diseases and cancer, dental applications and tissue regeneration: a review

in Pharmaceutical Innovation

Ali Sobhani-Nasab
Hamid Reza Banafshe
Amir Atapour
Mahmood Khaksary Mahabady
Maryam Akbari
Abdolreza Daraei
Yaser Mansoori
Amin Moradi Hasan-Abad

Frontiers in Medical Technology

doi 10.3389/fmedt.2023.1330007

3,484 views

Editorial

Published on 12 May 2023

Editorial: Innovative approaches in drug discovery and development

in Pharmaceutical Innovation

Qasem Ramadan
Diego Romano Perinelli
Laura Orian
Sara Baratchi

Frontiers in Medical Technology

doi 10.3389/fmedt.2023.1206088

2,980 views
2 citations

Methods

Published on 26 Jan 2023

Novel and efficient method for the reconstruction of adenoviruses through isothermal assembly and its potential applications

in Pharmaceutical Innovation

Ke Wen
Matthew D. Resch
Ryan Mazboudi
Hannah Mulhall Maasz
Jose M. Galarza

Frontiers in Medical Technology

doi 10.3389/fmedt.2023.1095198

2,856 views
3 citations

Opinion

Published on 16 Dec 2022

A proof-of-concept study poised to remodel the drug development process

in Pharmaceutical Innovation

Zaher Nahle

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.1053588

5,670 views
5 citations

Review

Published on 21 Oct 2022

Sourcing cells for in vitro models of human vascular barriers of inflammation

in Pharmaceutical Innovation

Molly C. McCloskey
Victor Z. Zhang
S. Danial Ahmad
Samuel Walker
Samantha S. Romanick
Hani A. Awad
James L. McGrath

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.979768

6,439 views
1 citation

Original Research

Published on 05 Oct 2022

SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibility

in Pharmaceutical Innovation

Mariana Valério
Luís Borges-Araújo
Manuel N. Melo
Diana Lousa
Cláudio M. Soares

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.1009451

5,393 views
12 citations

Perspective

Published on 01 Aug 2022

Improving treatment for acute ischemic stroke—Clot busting innovation in the pipeline

in Pharmaceutical Innovation

Joanna Shu Ting Liu
Yiran Ding
Simone Schoenwaelder
Xuyu Liu

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.946367

5,037 views
5 citations

Original Research

Published on 15 Jul 2022

Multiphysics pharmacokinetic model for targeted nanoparticles

in Pharmaceutical Innovation

Emma M. Glass
Sahil Kulkarni
Christina Eng
Shurui Feng
Avishi Malaviya
Ravi Radhakrishnan

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.934015

3,183 views
4 citations

Original Research

Published on 04 Apr 2022

Effect of Patent Expiry on the Performance of Innovator Multinational Pharmaceutical Companies in a Low Middle Income Country

in Pharmaceutical Innovation

Farrukh Khalil
Joseph Odhiambo Onyango

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.783460

11,881 views
3 citations

Original Research

Published on 28 Mar 2022

Identification of 1, 2, 4-Triazine and Its Derivatives Against Lanosterol 14-Demethylase (CYP51) Property of Candida albicans: Influence on the Development of New Antifungal Therapeutic Strategies

in Pharmaceutical Innovation

Abhishek Kumar Verma
Aarfah Majid
Md. Shahadat Hossain
SK. Faisal Ahmed
Mohammad Ashid
Ali Asger Bhojiya
Sudhir K. Upadhyay
Naveen Kumar Vishvakarma
Mudassir Alam

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.845322

4,261 views
11 citations

Editorial

Published on 04 Feb 2022

Editorial: Computational Approaches to Foster Innovation in the Treatment and Diagnosis of Infectious Diseases

in Pharmaceutical Innovation

Diana Lousa
Cláudio M. Soares
Fernando L. Barroso da Silva

Frontiers in Medical Technology

doi 10.3389/fmedt.2022.841088

1,049 views
2 citations

Perspective

Published on 14 Dec 2021

Recapitulating Trafficking of Nucleosides Into the Active Site of Polymerases of RNA Viruses: The Challenge and the Prize

in Pharmaceutical Innovation

Yves Boulard
Stéphane Bressanelli

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.705875

2,271 views
1 citation

Editorial

Published on 28 Oct 2021

Editorial: DNA Vaccines

in Pharmaceutical Innovation

Ada Maria de Barcelos Alves
Silvia Beatriz Boscardin
Annie Elong Ngono

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.782986

1,865 views

Mini Review

Published on 20 Oct 2021

Lactobacilli as Anti-biofilm Strategy in Oral Infectious Diseases: A Mini-Review

in Pharmaceutical Innovation

Barbara Giordani
Carola Parolin
Beatrice Vitali

Frontiers in Medical Technology

doi 10.3389/fmedt.2021.769172

7,747 views
23 citations

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Articles

Bioanalytical Method development, in-vivo pharmacokinetic evaluation, exvivo platelet aggregation inhibition activity of a novel solid dispersion formulation of Ticagrelor

Cost-effective track and trace technology for poor-quality chemotherapeutic pharmaceuticals in resource-limited countries: a review of the Chemotherapeutic Paper Analytical Device

The use of nanoparticles in the treatment of infectious diseases and cancer, dental applications and tissue regeneration: a review

Editorial: Innovative approaches in drug discovery and development

Novel and efficient method for the reconstruction of adenoviruses through isothermal assembly and its potential applications

A proof-of-concept study poised to remodel the drug development process

Sourcing cells for in vitro models of human vascular barriers of inflammation

SARS-CoV-2 variants impact RBD conformational dynamics and ACE2 accessibility

Improving treatment for acute ischemic stroke—Clot busting innovation in the pipeline

Multiphysics pharmacokinetic model for targeted nanoparticles

Effect of Patent Expiry on the Performance of Innovator Multinational Pharmaceutical Companies in a Low Middle Income Country

Identification of 1, 2, 4-Triazine and Its Derivatives Against Lanosterol 14-Demethylase (CYP51) Property of Candida albicans: Influence on the Development of New Antifungal Therapeutic Strategies

Editorial: Computational Approaches to Foster Innovation in the Treatment and Diagnosis of Infectious Diseases

Recapitulating Trafficking of Nucleosides Into the Active Site of Polymerases of RNA Viruses: The Challenge and the Prize

Editorial: DNA Vaccines

Lactobacilli as Anti-biofilm Strategy in Oral Infectious Diseases: A Mini-Review