Original Research

Accepted on 03 Jan 2025

Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning

in Systems Immunology

Ci Zou
Tao Zhou
Can Zhu
Qiongfang Wu
Mingqiang Deng
Zhiwei Jiang
Longfei Peng
Hao Geng
Wei Zhang
Zhouting Tuo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1511529

Original Research

Published on 03 Jan 2025

Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing

in Systems Immunology

Yafeng Jiang
Zhaolan Hu
Roujie Huang
Kaying Ho
Pengfei Wang
Jin Kang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512483

189 views

Original Research

Accepted on 26 Dec 2024

Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts' blood cells in space

in Systems Immunology

Maria Moreno-Villanueva
Luis Jimenez-Chavez
Stephanie Krieger
Lianghao Ding
Ye Zhang
Adriana Babiak-Vazquez
Mark Berres
Sandra Splinter
Kristen E Pauken
Brian C. Schaefer

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512578

100 views

Mini Review

Accepted on 24 Dec 2024

Tuberculous Meningitis Diagnosis and Treatment: Classic Approaches and High-Throughput Pathways

in Systems Immunology

Fangbo Lin

Frontiers in Immunology

doi 10.3389/fimmu.2024.1543009

Original Research

Accepted on 24 Dec 2024

Feature Selection Enhances Peptide Binding Predictions for TCR-Specific Interactions

in Systems Immunology

Hamid Teimouri
Zahra S Ghoreyshi
Anatoly B Kolomeisky
Jason T George

Frontiers in Immunology

doi 10.3389/fimmu.2024.1510435

Original Research

Accepted on 24 Dec 2024

Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia

in Systems Immunology

Rong Lin
Xiaoying Weng
Liang Lin
Xuyang Hu
Zhiyan Liu
Jing Zheng
Fenfang Shen
Rui Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1453633

Original Research

Accepted on 23 Dec 2024

Immunometabolic Alterations in Type 2 Diabetes Mellitus Revealed by Single-Cell RNA Sequencing: Insights into Subtypes and Therapeutic Targets

in Systems Immunology

Huahua Li
Lingling Zou
Zhaowei Long
Junkun Zhan

Frontiers in Immunology

doi 10.3389/fimmu.2024.1537909

Original Research

Published on 23 Dec 2024

Geny: a genotyping tool for allelic decomposition of killer cell immunoglobulin-like receptor genes

in Systems Immunology

Qinghui Zhou
Mazyar Ghezelji
Ananth Hari
Michael K. B. Ford
Connor Holley
S. Cenk Sahinalp
Ibrahim Numanagić

Frontiers in Immunology

doi 10.3389/fimmu.2024.1494995

150 views

Original Research

Accepted on 19 Dec 2024

Network Pharmacology and Multi-Omics Validation of the Jianpi-Yishen Formula in the Treatment of Chronic Kidney Disease

in Systems Immunology

Yuyan Li
Yueming Luo
Yilan Hu
Siting Li
Guandong Li
Wanyangchuan Zhang
Xiufen Gu
Jianting Wang
Shunmin Li
Hong Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2024.1512519

Original Research

Accepted on 17 Dec 2024

Unravelling the Impact of SARS-CoV-2 on Hemostatic and Complement Systems: A Systems Immunology Perspective

in Systems Immunology

DIDAR MURAD
Rehan Zafar Paracha
Maryum Nisar

Frontiers in Immunology

doi 10.3389/fimmu.2024.1457324

120 views

Original Research

Accepted on 16 Dec 2024

Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases

in Systems Immunology

Cheng-Cheng Deng
Xue-Yan Xu
Yan Zhang
Long-Can Liu
Xuan Wang
Jun-Yi Chen
Liu-Yi Yao
Ding-Heng Zhu
Bin Yang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1522076

Original Research

Accepted on 16 Dec 2024

Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anticitrullinated peptide antibody-positive early rheumatoid arthritis

in Systems Immunology

Bong-Ki Hong
Sungyong You
Jung Gon Kim
Naeun Lee
Kijun Lee
In-Pyo Baek
Ji Hyeon Ju
Wan-Uk Kim
Ho-Youn Kim

Frontiers in Immunology

doi 10.3389/fimmu.2024.1439082

Original Research

Accepted on 12 Dec 2024

Drp1-Associated Genes Implicated in Sepsis Survival

in Systems Immunology

Marissa D Pokharel
Anlin Feng
Ying Liang
Wenli Ma
Saurabh Aggarwal
Hoshang J Unwalla
Steve Black
Ting Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1516145

Original Research

Published on 11 Dec 2024

Nervonic acid alleviates radiation-induced early phase lung inflammation by targeting macrophages activation in mice

in Systems Immunology

Chenlin Wang
Yanan Wu
Chao Liu
Yang Li
Song Mi
Xiaofan Yang
Tong Liu
Yuanjing Tian
YingYing Zhang
Pingping Hu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1405020

369 views

Original Research

Accepted on 10 Dec 2024

Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks

in Systems Immunology

Dakota Paine
Meghan E Hermance
Saravanan Thangamani

Frontiers in Immunology

doi 10.3389/fimmu.2024.1511132

Original Research

Accepted on 09 Dec 2024

Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1 infected women is associated with lower viral loads

in Systems Immunology

Elina El-Badry
Luxiao Chen
Khader Ghneim
Ziyi Li
Kelsie Brooks
Jake William Rhodes
Rafick-Pierre Sekaly
William Kilembe
Susan Allen
Hao Wu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1507530

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Articles

Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning

Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing

Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts' blood cells in space

Tuberculous Meningitis Diagnosis and Treatment: Classic Approaches and High-Throughput Pathways

Feature Selection Enhances Peptide Binding Predictions for TCR-Specific Interactions

Identification and preliminary validation of biomarkers associated with mitochondrial and programmed cell death in pre-eclampsia

Immunometabolic Alterations in Type 2 Diabetes Mellitus Revealed by Single-Cell RNA Sequencing: Insights into Subtypes and Therapeutic Targets

Geny: a genotyping tool for allelic decomposition of killer cell immunoglobulin-like receptor genes

Network Pharmacology and Multi-Omics Validation of the Jianpi-Yishen Formula in the Treatment of Chronic Kidney Disease

Unravelling the Impact of SARS-CoV-2 on Hemostatic and Complement Systems: A Systems Immunology Perspective

Single-cell RNA-seq reveals immune cell heterogeneity and increased Th17 cells in human fibrotic skin diseases

Upregulation of interferon-γ response genes in monocytes and T cells identified by single-cell transcriptomics in patients with anticitrullinated peptide antibody-positive early rheumatoid arthritis

Drp1-Associated Genes Implicated in Sepsis Survival

Nervonic acid alleviates radiation-induced early phase lung inflammation by targeting macrophages activation in mice

Early transcriptomic changes at the skin interface during Powassan virus transmission by Ixodes scapularis ticks

Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1 infected women is associated with lower viral loads