Frontiers in Immunology | Primary Immunodeficiencies

Original Research

Published on 16 Oct 2024

The impact of immune dysregulation on the risk of malignancy in common variable immunodeficiency: insights from a multicenter study

in Primary Immunodeficiencies

Marta Dafne Cabañero-Navalon
Victor Garcia-Bustos
Héctor Balastegui-Martin
Carmen Bracke
Lourdes Mateu
Xavier Solanich
Juan Luis Carrillo-Linares
Angel Robles-Marhuenda
Francesc Puchades
Ana Pelaez Ballesta

Frontiers in Immunology

doi 10.3389/fimmu.2024.1465159

1,622 views

Review

Published on 14 Oct 2024

Functional role of UNC13D in immune diseases and its therapeutic applications

in Primary Immunodeficiencies

Van-Thanh Duong
Dongjun Lee
Yun Hak Kim
Sae-Ock Oh

Frontiers in Immunology

doi 10.3389/fimmu.2024.1460882

2,810 views

Original Research

Published on 10 Oct 2024

Sentiment analysis of subcutaneous and intravenous immunoglobulin therapy: public healthcare perception through social media discourse

in Primary Immunodeficiencies

Alejandro Tarango-García
Silvia Rodríguez-Narciso
Netzahualcóyotl Castañeda-Leyva
Hannia M. Prieto-Nevárez
Saul O. Lugo Reyes
Francisco J. Espinosa-Rosales
Sara Elva Espinosa-Padilla
Aidé T. Staines-Boone
Luis F. Torres-Bernal
Aristóteles Álvarez-Cardona

Frontiers in Immunology

doi 10.3389/fimmu.2024.1467852

990 views

Perspective

Published on 02 Oct 2024

Newborn screening for severe combined immunodeficiency in Malaysia: current status, challenges and progress

in Primary Immunodeficiencies

Wai Leng Chang
Lokman Mohd Noh
Amir Hamzah Abdul Latiff
Kent Chee Keen Woo
Intan Hakimah Ismail
Intan Juliana Abd Hamid
Sangeetha Siniah
Mohd Azri Zainal Abidin
Marina Sham
Adiratna Mat Ripen

Frontiers in Immunology

doi 10.3389/fimmu.2024.1456769

1,265 views

Original Research

Published on 02 Oct 2024

Newborn screening for SCID: the very first prospective pilot study from Türkiye

in Primary Immunodeficiencies

Sule Haskologlu
Senem Kocak
Lale Satiroglu Tufan
Fethiye Eken Aksoy
Dilan Bastug
Deniz Aslar Oner
Candan Islamoglu
Kubra Baskin
Saliha Esenboga
Deniz Acican

Frontiers in Immunology

doi 10.3389/fimmu.2024.1384195

1,832 views

Case Report

Published on 27 Sep 2024

Lanadelumab in a kidney transplant patient with hereditary angioedema due to C1-inhibitor deficiency and high cardiovascular risk - a case report

in Primary Immunodeficiencies

Antonio Gidaro
Leyla La Cava
Mattia Donadoni
Valentina Popescu Janu
Chiara Cogliati
Antonio Luca Brucato
Andrea Zanichelli
Mauro Cancian
Emanuele Bizzi

Frontiers in Immunology

doi 10.3389/fimmu.2024.1472390

1,547 views

Case Report

Published on 18 Sep 2024

Case report: Artificial thymic organoids facilitate clinical decisions for a patient with a TP63 variant and severe persistent T cell lymphopenia

in Primary Immunodeficiencies

Alevtina Gall
Marita Bosticardo
Stacey Ma
Karin Chen
Kayla Amini
Francesca Pala
Ottavia M. Delmonte
Tara Wenger
Michael Bamshad
John Sleasman

Frontiers in Immunology

doi 10.3389/fimmu.2024.1438383

1,720 views

Original Research

Published on 10 Sep 2024

Investigating pulmonary and non-infectious complications in common variable immunodeficiency disorders: a UK national multi-centre study

in Primary Immunodeficiencies

Heba M. Bintalib
Sofia Grigoriadou
Smita Y. Patel
Leman Mutlu
Kavitha Sooriyakumar
Prashantha Vaitla
Elizabeth McDermott
Elizabeth Drewe
Cathal Steele
Manisha Ahuja

Frontiers in Immunology

doi 10.3389/fimmu.2024.1451813

2,107 views

Correction

Published on 05 Sep 2024

Corrigendum: Abnormalities of thymic stroma may contribute to immune dysregulation in murine models of leaky severe combined immunodeficiency

in Primary Immunodeficiencies

Francesca Rucci
Pietro Luigi Poliani
Stefano Caraffi
Tiziana Paganini
Elena Fontana
Silvia Giliani
Frederick W. Alt
Luigi Daniele Notarangelo

Frontiers in Immunology

doi 10.3389/fimmu.2024.1467807

723 views

Case Report

Published on 02 Sep 2024

Case report: Granulocyte-macrophage colony-stimulating factor sargramostim did not rescue the neutrophil phenotype in two patients with JAGN1-mutant severe congenital neutropenia

in Primary Immunodeficiencies

Susan Farmand
Susanne Eva Aydin
Katharina Wustrau
Svea Böhm
Francis Ayuk
Gabriele Escherich
Julia Skokowa
Ingo Müller
Kai Lehmberg

Frontiers in Immunology

doi 10.3389/fimmu.2024.1373495

1,132 views
1 citation

Original Research

Published on 29 Aug 2024

Human papillomavirus disease in GATA2 deficiency: a genetic predisposition to HPV-associated female anogenital malignancy

in Primary Immunodeficiencies

Ehren Dancy
Pamela Stratton
Dominique C. Pichard
Beatriz E. Marciano
Edward W. Cowen
Alison A. McBride
Koenraad Van Doorslaer
Melissa A. Merideth
Noemi Salmeri
Marybeth S. Hughes

Frontiers in Immunology

doi 10.3389/fimmu.2024.1445711

2,335 views
1 citation

Case Report

Published on 26 Aug 2024

Case report: Deep sequencing and long-read genome sequencing refine prior genetic analyses in families with apparent gonadal mosaicism in PIK3CD-related activated PI3K delta syndrome

in Primary Immunodeficiencies

Halyn Orellana
Jia Yan
Alex Paul
Mari Tokita
Yan Ding
Rajarshi Ghosh
Katie L. Lewis
Joie Davis
Leila Jamal
Colleen Jodarski

Frontiers in Immunology

doi 10.3389/fimmu.2024.1451212

1,155 views

Original Research

Published on 23 Aug 2024

JAK inhibitors to treat STAT3 gain-of-function: a single-center report and literature review

in Primary Immunodeficiencies

Faranaz Atschekzei
Stephan Traidl
Julia Carlens
Katharina Schütz
Sandra von Hardenberg
Abdulwahab Elsayed
Diana Ernst
Linus Risser
Thea Thiele
Theresa Graalmann

Frontiers in Immunology

doi 10.3389/fimmu.2024.1400348

2,551 views
3 citations

Original Research

Published on 20 Aug 2024

Unraveling the unphosphorylated STAT3–unphosphorylated NF-κB pathway in loss of function STAT3 Hyper IgE syndrome

in Primary Immunodeficiencies

Adil Karim
Rashi Garg
Biman Saikia
Abha Tiwari
Smrity Sahu
Mehak Malhotra
Ranjana W. Minz
Amit Rawat
Surjit Singh
Deepti Suri

Frontiers in Immunology

doi 10.3389/fimmu.2024.1332817

1,851 views

Original Research

Published on 19 Aug 2024

MicroRNA dysregulation in ataxia telangiectasia

in Primary Immunodeficiencies

Emilia Cirillo
Antonietta Tarallo
Elisabetta Toriello
Annamaria Carissimo
Giuliana Giardino
Antonio De Rosa
Carla Damiano
Annarosa Soresina
Raffaele Badolato
Rosa Maria Dellepiane

Frontiers in Immunology

doi 10.3389/fimmu.2024.1444130

1,659 views

Editorial

Published on 19 Aug 2024

Editorial: Transition care in primary immunodeficiencies

in Primary Immunodeficiencies

Siobhan Oisin Burns
Nizar Mahlaoui

Frontiers in Immunology

doi 10.3389/fimmu.2024.1467284

889 views