Frontiers in Immunology | Parasite Immunology

Original Research

Accepted on 04 Apr 2025

Different pathways responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models

in Parasite Immunology

Ana Carolina Leão
Maria Jose Villar
Rakesh Adhikari
Cristina Poveda
Leroy Versteeg
Gregório Almeida
Peter J Hotez
Maria Elena Bottazzi
Kathryn Marie Jones

Frontiers in Immunology

doi 10.3389/fimmu.2025.1487317

Original Research

Published on 03 Apr 2025

Characteristics and immunoprotective functions of three cysteine proteases from Clonorchis sinensis

in Parasite Immunology

Yunliang Shi
Xiaoqin Li
Kai Liang
Ting Lu
Yu Chen
Yashi Lai
Yaoting Li
Shuai Wei
Shanshan He
Lili Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550775

222 views

Original Research

Accepted on 01 Apr 2025

Self and parasite-derived peptides selected upon DERAA-bearing HLA-DRB1 alleles activate CD4+ T cells from Chagas cardiomyopathy patients and are associated with ventricular dysfunction

in Parasite Immunology

Thaiany Souza-Silva
Eula Graciele Amorim Neves
Andrea Teixeira-Carvalho
Amanda Figueiredo
Katia Luciano Morais
Juliana Apostólico
Hélcio Rodrigues
Jorge Kalil
Maria Aparecida Juliano
Luiz Juliano

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527115

Review

Published on 27 Mar 2025

Ticks’ tricks: immunomodulatory effects of ixodid tick saliva at the cutaneous tick-host interface

in Parasite Immunology

Lisa Kleissl
Sophie Weninger
Florian Winkler
Margarida Ruivo
Michiel Wijnveld
Johanna Strobl

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520665

518 views

Original Research

Published on 27 Mar 2025

A secreted helminth microRNA suppresses gastrointestinal cell differentiation required for innate immunity

in Parasite Immunology

Matias G. Perez
Victoria Gillan
William M. Anderson
François Gerbe
Fabien Herbert
Tom N. McNeilly
Rick M. Maizels
Philippe Jay
Eileen Devaney
Collette Britton

Frontiers in Immunology

doi 10.3389/fimmu.2025.1558132

578 views

Original Research

Accepted on 25 Mar 2025

Krameria lappacea roots extract to rescue coccidiosis-mediated inflammation in the jejunum of C57BL/6 mice

in Parasite Immunology

Rewaida Abdel-Gaber
Ghada Alamari
Mohamed A Dkhil
Saeed El-Ashram
Nawal Al- Hoshani
Esam Al-shaebi
Saleh Al-Quraishy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557235

Original Research

Published on 25 Mar 2025

Plasmodium falciparum reticulocyte-binding homologues are targets of human inhibitory antibodies and play a role in immune evasion

in Parasite Immunology

Linda Reiling
Kristina E. M. Persson
Fiona J. McCallum
Nimmo Gicheru
Samson M. Kinyanjui
Chetan E. Chitnis
Freya J. I. Fowkes
Kevin Marsh
James G. Beeson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532451

523 views

Review

Accepted on 24 Mar 2025

Helminth-Induced Immune Modulation in Colorectal Cancer: Exploring Therapeutic Applications

in Parasite Immunology

Hongyu Li
Chaojun Shan
Yunhuan Zhu
Xiaodong Yao
Lijun Lin
Yuncheng Qian
Yuqing Wang
Jialu Xu
Yijie Zhang
Hairun Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1484686

114 views

Original Research

Published on 24 Mar 2025

Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis

in Parasite Immunology

Tao Sun
Xiaojuan Bi
Ning Yang
Xue Zhang
Jin Chu
Liang Li
Hui Liu
Rui Tang
Renyong Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1518586

419 views

Original Research

Published on 21 Mar 2025

HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection

in Parasite Immunology

Lucy G. Fry
Charity L. Washam
Hayden Roys
Anne K. Bowlin
Gopinath Venugopal
Jordan T. Bird
Stephanie D. Byrum
Tiffany Weinkopff

Frontiers in Immunology

doi 10.3389/fimmu.2025.1487311

437 views

Original Research

Accepted on 18 Mar 2025

Spleen and Peripheral Blood Immunopathology in a Standard Outbred Model of Adult-Stage Murine Schistosomiasis

in Parasite Immunology

Thomas T. Schulze
Andrew J. Neville
Evie G. Ehrhorn
Sarah A. Alsuleiman
Jonathan L. Vennerstrom
Paul H. Davis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527129

106 views

Review

Published on 12 Mar 2025

Insights to the HIV-associated visceral leishmaniasis clinical outcome: lessons learned about immune mediated disorders

in Parasite Immunology

Maria Luciana Silva-Freitas
Gabriela Corrêa-Castro
Alda Maria Da-Cruz
Joanna Reis Santos-Oliveira

Frontiers in Immunology

doi 10.3389/fimmu.2025.1516176

476 views

Original Research

Published on 07 Mar 2025

Profile of soluble cell adhesion molecules as potential biomarkers in the cardiac stages of chronic Chagas disease

in Parasite Immunology

Victor Vaitkevicius-Antão
Bruno Almeida Silva
Michelle da Silva Barros
Cíntia Nascimento da Costa-Oliveira
Byannca de Carvalho Torreão
Ana Carla da Silva
Silvia Marinho Martins
Cristina Carrazone
Wilson Oliveira
Carolina de Araújo Medeiros

Frontiers in Immunology

doi 10.3389/fimmu.2025.1541860

694 views

Original Research

Published on 28 Feb 2025

Reduced plasma levels of GM-CSF is a common feature of Schistosoma mansoni-infected school-aged children

in Parasite Immunology

Severin Donald Kamdem
Leonel Meyo Kamguia
Alim Oumarou
Bernard Marie Zambo Bitye
Katie Lennard
Frank Brombacher
Thomas Spangenberg
Claudia Demarta-Gatsi
Justin Komguep Nono

Frontiers in Immunology

doi 10.3389/fimmu.2025.1474575

859 views

Original Research

Published on 28 Feb 2025

Liver-draining portal lymph node responds to enteric nematode infection by generating highly parasite-specific follicular T helper and B cell responses

in Parasite Immunology

Joshua Adjah
Zaneta D. Musimbi
Robert M. Mugo
Ankur Midha
Susanne Hartmann
Sebastian Rausch

Frontiers in Immunology

doi 10.3389/fimmu.2025.1483274

633 views

Original Research

Published on 28 Feb 2025

Identification and validation of protective glycoproteins in Haemonchus contortus H11

in Parasite Immunology

Hui Liu
Yao Zhang
Jiarui Li
Feng Liu
Lisha Ye
Xin Liu
Chunqun Wang
Min Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1521022

636 views