Frontiers in Immunology | NK and Innate Lymphoid Cell Biology

Perspective

Accepted on 30 Oct 2025

Perspective: IL-15 Cytokine-Armored NK Cells as Ready-to-Use Immunotherapy for Diverse Malignancies: Therapeutic Potential and Toxicity Risks

in NK and Innate Lymphoid Cell Biology

SCOTT BAUGHAN
Tim Folsom
Matt Johnson
Joshua Kreuger
Beau Webber
Branden Scott Moriarity

Frontiers in Immunology

150 views

Original Research

Published on 24 Oct 2025

Comparative transcriptomic analysis of tumor- infiltrating canine natural killer cells and candidate biomarkers from first-in-dog NK immunotherapy trials

in NK and Innate Lymphoid Cell Biology

Aryana M. Razmara
Marshall Lammers
Sean J. Judge
Cyrus J. Sholevar
William J. Murphy
Cameron E. Gaskill
William T. N. Culp
Alicia A. Gingrich
Zachary S. Morris
Robert B. Rebhun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646849

666 views

Systematic Review

Published on 23 Oct 2025

New hope for the treatment of recurrent and refractory psoriasis: NK cell immunotherapy—A scientometric analysis

in NK and Innate Lymphoid Cell Biology

Li Chen
Lin Cheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656398

3,522 views

Original Research

Accepted on 22 Oct 2025

TGF-β-driven NK Cells plasticity in hepatocellular carcinoma

in NK and Innate Lymphoid Cell Biology

Valentina Reverberi
Anna Montali
Andrea Vecchi
Marzia Rossi
Alessio Pelagatti
Sara Doselli
Benedetta Farina
Andrea Olivani
Giorgio Economopoulos
Raffaele Dalla Valle

Frontiers in Immunology

345 views

Review

Published on 22 Oct 2025

Crosstalk between decidual natural killer cells and extravillous trophoblasts at the maternal-fetal interface: current status and future perspectives

in NK and Innate Lymphoid Cell Biology

Yeqi Qiu
Mingye Chen
Rong Lin
Xiaoyan Chen
Lichun He
Hui Yin
Xian Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1703156

551 views

Original Research

Accepted on 17 Oct 2025

Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms

in NK and Innate Lymphoid Cell Biology

Lillia A. Baird
Samuel J. Teener
Ian F. Webber-Davis
Andrew D. Carter
Fang Huang
Dae-Gyu Jang
Joshua P. Famie
Caroline E. Piecuch
Kai Guo
Eva Lucille Feldman

Frontiers in Immunology

234 views

Review

Published on 16 Oct 2025

Beyond CAR-T Cells: exploring CAR-NK, CAR-M, and CAR-γδ T strategies in solid tumor immunotherapy

in NK and Innate Lymphoid Cell Biology

Yingjie Hou
Shihua Hu
Chong Liu
Xin Chen
Yuru Wang
Youzherui Li
Zihe Fu
Chunjing Feng
Yanhua Gong
Zichuan Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675807

4,245 views

Original Research

Accepted on 09 Oct 2025

Insomnia and Anxiety: Exploring Their Hidden Effect on Natural Killer Cells Among Young Female Adults

in NK and Innate Lymphoid Cell Biology

Renad M. Alhamawi
Fatmah A. Halawani
Sima F. Hakeem
Hadeel A. Alslimi
Ebraheim M. Alhamawi
Ahmed M. Aljohani
Ibrahim N. Mohammed
Heba M. Zahid
Yahya A. Almutawif

Frontiers in Immunology

277 views

Original Research

Published on 07 Oct 2025

Dynamics of NK cell subsets following autologous hematopoietic stem cell transplantation in adult oncologic patients

in NK and Innate Lymphoid Cell Biology

Gabirel Astarloa-Pando
Victor Sandá
Ainhoa Amarilla-Irusta
Ainara Lopez-Pardo
Itxaso San Juan
Ainhoa Iturbe-Larrondo
Raquel Pérez-Garay
Silvia Pérez-Fernández
Borja Santos-Zorrozúa
Bárbara Manzanares-Martín

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629118

3,192 views

Review

Published on 06 Oct 2025

Unspoken words: decoding the dialog between type 2 innate lymphoid cells and T cells

in NK and Innate Lymphoid Cell Biology

Zahra Jamila Ikra
Qiutong Huang
Huiyang Yu
Gabrielle T. Belz
Craig N. Jenne
Nicolas Jacquelot

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677358

3,894 views

Mini Review

Published on 29 Sep 2025

Recent advances in feeder-free NK cell expansion as a future direction of adoptive cell therapy

in NK and Innate Lymphoid Cell Biology

Jimin Lee
Munsik Kim
Hanbin Jeong
Ilkoo Noh
Jeehun Park

Frontiers in Immunology

doi 10.3389/fimmu.2025.1675353

4,675 views

Original Research

Published on 10 Sep 2025

Peripheral blood iNKT cells display an activated profile with both increased apoptosis and dysfunction in obesity

in NK and Innate Lymphoid Cell Biology

Chloé Wilkin
Nathalie Esser
Cédric Lassence
Marion Bruneteaux
Marjorie Fadeur
Jenny De Flines
Nicolas Paquot
Jacques Piette
Sylvie Legrand-Poels

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651054

4,831 views

Review

Published on 12 Aug 2025

Natural killer cells in skin: a unique opportunity to better characterize the many facets of an overlooked secondary lymphoid organ

in NK and Innate Lymphoid Cell Biology

Kirsten M. Johnson
Dean A. Lee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646719

3,657 views
1 citation

Original Research

Published on 01 Aug 2025

Serum 17β-estradiol inversely correlates with circulating group 2 innate lymphoid cells in a cohort of asthmatic patients

in NK and Innate Lymphoid Cell Biology

Elizabeth J. Myers
Samuel E. Aamodt
Thomas P. Huecksteadt
Robert Paine
Mustafa Mir-Kasimov
Christopher A. Reilly
Sean J. Callahan
Karl A. Sanders
Kristi J. Warren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1555228

2,182 views

Original Research

Published on 25 Jul 2025

RAG recombinase expression discriminates the development of natural killer cells

in NK and Innate Lymphoid Cell Biology

Jasmin Sprissler
Ulrich Pannicke
Eva-Maria Rump
Hubert Schrezenmeier
Nicolas Casadei
Michaela Pogoda
Laurence Kuhlburger
Morgana Barroso Oquendo
Stefan Czemmel
Klaus-Michael Debatin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607664

1,958 views

Review

Published on 21 Jul 2025

Unraveling NK cell heterogeneity through single-cell sequencing: insights from physiological and tumor contexts for clinical applications

in NK and Innate Lymphoid Cell Biology

Mingxin Shen
Yutong Liu
Liang Shao
Meng Qu
Shixin Song
Wei Sun
Hao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612352

2,806 views
1 citation