Frontiers in Immunology | Multiple Sclerosis and Neuroimmunology

Original Research

Published on 07 Nov 2025

Prognostic value of kappa free light chain index in patients with primary progressive multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Martin Schmidauer
Klaus Berek
Michael Auer
Gabriel Bsteh
Paola Cavalla
Franziska Di Pauli
Massimiliano Di Filippo
Florian Deisenhammer
Andreja Emeršič
Fabian Föttinger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658182

412 views

Review

Accepted on 05 Nov 2025

Decoding tRNA Dynamics in Neuroimmune Disorders: Mechanistic Insights, Diagnostic Innovations, and Therapeutic Opportunities

in Multiple Sclerosis and Neuroimmunology

Enlin Liang
Wenya Wang
Li Zhang

Frontiers in Immunology

Original Research

Published on 04 Nov 2025

Sex differences in abnormal gluten response and predictors of gluten sensitivity in patients with schizophrenia

in Multiple Sclerosis and Neuroimmunology

Michał Dzikowski
Joanna Rog
Dariusz Juchnowicz
Anna Rymuszka
Hanna Karakula-Juchnowicz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1696763

339 views

Review

Published on 30 Oct 2025

The mechanisms of specialized pro-resolving mediators in pain relief: neuro-immune and neuroglial regulations

in Multiple Sclerosis and Neuroimmunology

Yushan Chen
Xuewei Wu
Jiaqi Li
Yuxuan Ren
He Miao
Xiaojie Zhai
Changshun Huang
Xiaowei Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634724

650 views

Mini Review

Accepted on 29 Oct 2025

Neuroimmune modulatory effects of the NLRP3 inflammasome: the role of sex and living environment in brain affecting conditions

in Multiple Sclerosis and Neuroimmunology

Miriam Ciani
Giovanna Rigillo
Beatrice Bertarini
Cristina Benatti
Silvia Alboni
FABIO TASCEDDA

Frontiers in Immunology

172 views

Original Research

Published on 29 Oct 2025

Antibodies to myelin oligodendrocyte glycoprotein in optic perineuritis

in Multiple Sclerosis and Neuroimmunology

Shanshan Cao
Yuan Zhang
Xintong Xu
Mingming Sun
Chunyan Pan
Yuhang Wang
Shihui Wei
Quangang Xu
Huanfen Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657600

461 views

Review

Accepted on 28 Oct 2025

Vaccination and COVID-19: Impact on Long-COVID

in Multiple Sclerosis and Neuroimmunology

Gustavo N Guimarães
Natália Silva Brunetti
Dieila Giomo de Lima
José Luiz Proença-Modena
Alessandro S Farias

Frontiers in Immunology

395 views

Review

Accepted on 28 Oct 2025

The critical role of Th17 cells and IL-17A in autoimmune and inflammation-associated neurological diseases: mechanisms and therapeutic perspectives

in Multiple Sclerosis and Neuroimmunology

Inmaculada Xu Lou
Huifen Zhou
Haitong Wan

Frontiers in Immunology

157 views

Original Research

Published on 28 Oct 2025

Intestinal mucosal alterations parallel central demyelination and remyelination: insights into the gut-brain axis in the cuprizone model of multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Carolina Ferreira
Filipa Carvalho
Pedro Vieira
André Alves
Filipe Palavra
Jani Almeida
Vera Alves
Ezequiel Coscueta
Patrícia Dias Pereira
Manuela Pintado

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682183

1,044 views

Correction

Accepted on 27 Oct 2025

Correction: Polysialic acid restrains inflammatory monocyte maturation

in Multiple Sclerosis and Neuroimmunology

INGREDY PASSOS
Benjamin Peschke
Shrey Gandhi
Judith Derdelinckx
Louisa Müller-Miny
Harald Neumann
Jan D Lünemann
Christian Keller

Frontiers in Immunology

154 views

Brief Research Report

Published on 27 Oct 2025

Combination therapy of ofatumumab and daratumumab in patients with severe anti-NMDA receptor encephalitis

in Multiple Sclerosis and Neuroimmunology

Baojie Wang
Yufeng Chu
Chao Zhang
Shougang Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681884

572 views

Original Research

Published on 27 Oct 2025

The ATP-mediated cytokine release by macrophages is down-modulated by unconventional α9* nicotinic acetylcholine receptors

in Multiple Sclerosis and Neuroimmunology

Philipp M. K. Wolf
Dominik Hanke
Vijay K. Singh
Hanno L. Keller
Luca J. Ettischer
Laura Teppe
Anca-Laura Amati
Andreas Hecker
Faeq Husain-Syed
Marius Rohde

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661114

761 views

Original Research

Published on 27 Oct 2025

The diagnostic and prognostic value of CXCL13, CXCL10, and CXCL8 in patients with neurosyphilis

in Multiple Sclerosis and Neuroimmunology

Hongjing Guan
Jingli Peng
Zihao Xia
Xiaoyun Di
Qin Wang
Chunmiao Zou
Rentian Cai
Chen Chen
Hongxia Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654251

689 views

Original Research

Published on 22 Oct 2025

Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040

in Multiple Sclerosis and Neuroimmunology

Peixi Zhao
Chang Guan
Jing Lu
Ying Zhang
Baitong Wang
Lin Huang
Ding Ye
Hongmei Nan
Jian Wang
Peng Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685316

547 views

Study Protocol

Published on 22 Oct 2025

The efficacy, safety, and pharmacokinetics/pharmacodynamics of telitacicept following efgartigimod in generalized myasthenia gravis: protocol of a randomized controlled trial

in Multiple Sclerosis and Neuroimmunology

Jia Li
Yuan Zhang
Yan Deng
Wenyu Li
Yiqi Wang
Feiteng Qi
Qiaoyi Zhang
Bingbing Wan
Xiang Li
Yiyun Weng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604786

1,041 views

Original Research

Accepted on 20 Oct 2025

Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD

in Multiple Sclerosis and Neuroimmunology

Hyun-ju Lee
Sora Kang
Yoo Jin Lee
Tae-Mi Jung
Bitna Joo
Jeong-Woo Hwang
Yu-Jin Kim
Ji-Yeong Jang
Jeongseop Kim
Jeong-Heon Song

Frontiers in Immunology

150 views