Frontiers in Immunology | Molecular Innate Immunity

Original Research

Published on 24 Jan 2025

Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance

in Molecular Innate Immunity

Santiago Rodríguez de Córdoba
Andrea Reparaz
Daniel Sanchez
Sheila Pinto
Lucia Juana Lopez
Héctor Martin Merinero
Iria Calvete
Julian Perez-Perez
Sydney S. Jellison
Yuzhou Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1527016

310 views

Original Research

Published on 24 Jan 2025

Ochratoxin A induces immunotoxicity by targeting Annexin A1 mediated neutrophil apoptosis in zebrafish

in Molecular Innate Immunity

Yihong Zheng
Yinuo Liu
Jin Tian
Shuhong Liu
Gaowei Ma
Yupeng Xie
Chenhua Zheng
Zekai Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1542964

250 views

Original Research

Accepted on 23 Jan 2025

The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells

in Molecular Innate Immunity

Angela Armento
Inga Sonntag
Ana-Cristina Almansa-Garcia
Merve Sen
Sylvia Bolz
Blanca Arango-Gonzalez
Ellen Kilger
Ruchi Sharma
Kapil Bharti
Rosario Fernández Godino

Frontiers in Immunology

doi 10.3389/fimmu.2025.1527018

Original Research

Accepted on 23 Jan 2025

Association of high-sensitivity C-reactive protein with hepatic fibrosis in patients with metabolic dysfunction-associated steatotic liver disease

in Molecular Innate Immunity

Yunfei Wu
Guojun Zheng
Fan Zhang
Wenjian Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1544917

Original Research

Published on 23 Jan 2025

Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence

in Molecular Innate Immunity

Xiaoyin Wu
Buyu Guo
Xingyu Chang
Yuxuan Yang
Qianqian Liu
Jiahui Liu
Yichen Yang
Kang Zhang
Yumei Ma
Songbo Fu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1427626

304 views

Original Research

Published on 22 Jan 2025

Nanoparticles containing intracellular proteins modulate neutrophil functional and phenotypic heterogeneity

in Molecular Innate Immunity

Leonore Raudszus
Farbod Bahreini
Susanne Allan
Kai-Uwe Kalies
Charles C. Caldwell
Kathrin Kalies

Frontiers in Immunology

doi 10.3389/fimmu.2024.1494400

412 views

Original Research

Published on 21 Jan 2025

A randomized, placebo-controlled trial of the BTK inhibitor zanubrutinib in hospitalized patients with COVID-19 respiratory distress: immune biomarker and clinical findings

in Molecular Innate Immunity

Steven P. Treon
Camille N. Kotton
David J. Park
Giorgia Moranzoni
Camilla K. Lemvigh
Joseph C. Gathe
Tilly A. Varughese
Christopher F. Barnett
Johnny M. Belenchia
Nina M. Clark

Frontiers in Immunology

doi 10.3389/fimmu.2024.1369619

440 views

Editorial

Accepted on 20 Jan 2025

Editorial: Immune Response Changes in Alcohol and non-Alcohol Associated Tissue Injury

in Molecular Innate Immunity

PAUL THOMES

Frontiers in Immunology

doi 10.3389/fimmu.2025.1559143

Review

Accepted on 20 Jan 2025

Multifaceted Roles of Ninjurin1 in Immunity, Cell Death, and Disease

in Molecular Innate Immunity

Lili Zhu
Yunfei Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519519

Original Research

Accepted on 20 Jan 2025

Balancing Inflammation: The Specific Roles of Serum Amyloid A Proteins in Sterile and Infectious Diseases

in Molecular Innate Immunity

Tirthankar Mohanty
Katarina Miličević
Henri Göthert
Andreas Tillmann
Médea Padra
Praveen Papareddy
Heiko Herwald

Frontiers in Immunology

doi 10.3389/fimmu.2025.1544085

Mini Review

Accepted on 20 Jan 2025

The role of cGAS-STING pathway ubiquitination in innate immunity and multiple diseases

in Molecular Innate Immunity

Chunyan Deng
Dongyan Chen
Liang Yang
Yubiao Zhang
Cheng Jin
Yue Li
Qihong Lin
Mingjing Luo
Ruihao Zheng
Baozhen Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1522200

Original Research

Published on 20 Jan 2025

TLR10 overexpression modulates immune response in A549 lung epithelial cells challenged with SARS-CoV-2 S and N proteins

in Molecular Innate Immunity

Špela Knez
Mojca Narat
Jernej Ogorevc

Frontiers in Immunology

doi 10.3389/fimmu.2024.1490478

477 views

Original Research

Published on 17 Jan 2025

Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression of atherosclerotic plaque

in Molecular Innate Immunity

Yifeng Zhang
Shuxian Lu
Liang Qiu
Manman Qin
Dan Shan
Lianhua Xie
Yao Yi
Jun Yu

Frontiers in Immunology

doi 10.3389/fimmu.2024.1528475

350 views

Review

Published on 17 Jan 2025

Macrophage-derived extracellular vesicles as new players in chronic non-communicable diseases

in Molecular Innate Immunity

Fengjuan Lin
Huiyu Luo
Jiexian Wang
Qing Li
Longying Zha

Frontiers in Immunology

doi 10.3389/fimmu.2024.1479330

282 views

Original Research

Published on 16 Jan 2025

Potential implications of granzyme B in keloids and hypertrophic scars through extracellular matrix remodeling and latent TGF-β activation

in Molecular Innate Immunity

Alexandre Aubert
Jenna Goeres
Amy Liu
Martin Kao
Katlyn C. Richardson
Karen Jung
Boris Hinz
Richard I. Crawford
David J. Granville

Frontiers in Immunology

doi 10.3389/fimmu.2024.1484462

268 views

Review

Published on 14 Jan 2025

Mitochondrial dysfunction in Alzheimer’s disease: a key frontier for future targeted therapies

in Molecular Innate Immunity

Shuguang Wang
Zuning Liao
Qiying Zhang
Xinyuan Han
Changqing Liu
Jin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1484373

222 views

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Articles

Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance

Ochratoxin A induces immunotoxicity by targeting Annexin A1 mediated neutrophil apoptosis in zebrafish

The AMD-associated genetic polymorphism CFH Y402H confers vulnerability to Hydroquinone-induced stress in iPSC-RPE cells

Association of high-sensitivity C-reactive protein with hepatic fibrosis in patients with metabolic dysfunction-associated steatotic liver disease

Identification and validation of glycolysis-related diagnostic signatures in diabetic nephropathy: a study based on integrative machine learning and single-cell sequence

Nanoparticles containing intracellular proteins modulate neutrophil functional and phenotypic heterogeneity

A randomized, placebo-controlled trial of the BTK inhibitor zanubrutinib in hospitalized patients with COVID-19 respiratory distress: immune biomarker and clinical findings

Editorial: Immune Response Changes in Alcohol and non-Alcohol Associated Tissue Injury

Multifaceted Roles of Ninjurin1 in Immunity, Cell Death, and Disease

Balancing Inflammation: The Specific Roles of Serum Amyloid A Proteins in Sterile and Infectious Diseases

The role of cGAS-STING pathway ubiquitination in innate immunity and multiple diseases

TLR10 overexpression modulates immune response in A549 lung epithelial cells challenged with SARS-CoV-2 S and N proteins

Integrative single-cell and bulk RNA-seq analyses identify CD4+ T-cell subpopulation infiltration and biomarkers of regulatory T cells involved in mediating the progression of atherosclerotic plaque

Macrophage-derived extracellular vesicles as new players in chronic non-communicable diseases

Potential implications of granzyme B in keloids and hypertrophic scars through extracellular matrix remodeling and latent TGF-β activation

Mitochondrial dysfunction in Alzheimer’s disease: a key frontier for future targeted therapies