Frontiers in Immunology

Original Research

Accepted on 27 Mar 2025

Identification of Aging-Related Biomarkers for Intervertebral Disc Degeneration in Whole Blood Samples Based on Bioinformatics and Machine Learning

in Inflammation

Zi-hang Li
Shi-pian Li
Ya-hao Li
Yu-cheng Wang
Zhen-yu Tang
Kai-yang Xu
Xiao-rong Li
Zhen Tan
Jiao-yi Pan
Jin-tao Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565945

Review

Accepted on 27 Mar 2025

Targeting the Immuno-Inflammatory-Microbial Network: A Key Strategy for Sepsis Treatment

in Inflammation

Yue Xu
Jiaxin Wang
Rui Yuan
Zhu Qin
Kunlan Long
Peiyang Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575516

Review

Published on 27 Mar 2025

Interferon regulatory factor 5: a potential target for therapeutic intervention in inflammatory diseases

in Inflammation

Xinyuan Yu
Ata Ur Rehman
Lihong Dang
Xu Zhang
Jia Liu
Xiaoxing Xiong
Gang Chen
Zhihong Jian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535823

331 views

Original Research

Published on 27 Mar 2025

Differences in the inflammatory response and outcome among hospitalized patients during different waves of the COVID-19 pandemic

in Inflammation

Violeta Briciu
Daniel-Corneliu Leucuta
Monica Muntean
Amanda Radulescu
Cristina Cismaru
Adriana Topan
Lucia Herbel
Melinda Horvat
Mirela Flonta
Mihai Calin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545181

269 views

Original Research

Accepted on 25 Mar 2025

LncRNA29RIK in macrophages promotes LPS mediated sensitivity to obesity

in Inflammation

Rong Wang
Gao Yunhuan
Ya Wang
Zhang Yuan
Rongcun Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574507

Review

Published on 25 Mar 2025

Immune cells differentiation in osteoarthritic cartilage damage: friends or foes?

in Inflammation

Mingxiang Liu
Chaoqun Wu
Chaofan Wu
Zulong Zhou
Run Fang
Chenfeng Liu
Rende Ning

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545284

696 views

Review

Published on 25 Mar 2025

Mechanistic studies on the role of CHI3L1 in eosinophilic inflammation in chronic sinusitis

in Inflammation

Ling Guo
Yi Peng
Cheng Yang
Xinghong Liu
Weilan Xiong
Weijiang Liao
Jiangang Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1562546

300 views

Original Research

Published on 25 Mar 2025

Curcumin targets YAP1 to enhance mitochondrial function and autophagy, protecting against UVB-induced photodamage

in Inflammation

Quan Chen
Wenxin Lin
Yi Tang
Fengmei He
Bihua Liang
Jiaoquan Chen
Huaping Li
Huilan Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566287

466 views

Original Research

Published on 25 Mar 2025

Targeted inhibitors of S100A9 alleviate chronic pancreatitis by inhibiting M2 macrophage polarization via the TAOK3-JNK signaling pathway

in Inflammation

Xufeng Tao
Yu Wu
Fangyue Guo
Linlin Lv
Xiaohan Zhai
Dong Shang
Zhan Yu
Hong Xiang
Deshi Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526813

206 views

Mini Review

Accepted on 24 Mar 2025

Advances in cell therapy for orthopedic diseases: bridging immune modulation and regeneration

in Inflammation

Jing Wang
Shenghao Xu
Bo Chen
Yanguo Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567640

Original Research

Accepted on 24 Mar 2025

Acute myeloid leukemia-derived Extracellular Vesicles induced DNA methylation changes responsible for inflammatory program in normal Hematopoietic Stem Progenitor Cells

in Inflammation

Daniela Lamorte
Giovanni Calice
Stefania Trino
Michele Santodirocco
Antonella Caivano
Luciana De Luca
Ilaria Laurenzana

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569159

Original Research

Accepted on 24 Mar 2025

MCT4 inhibition attenuates inflammatory response to Mycobacterium avium paratuberculosis infection and restores intestinal epithelial integrity in vitro

in Inflammation

Ala' Alhendi
Saleh A Naser

Frontiers in Immunology

doi 10.3389/fimmu.2025.1562100

Case Report

Accepted on 24 Mar 2025

Case Report: Anti-Platelet Factor 4 -mediated immunothrombosis in a Patient with ANCA Vasculitis -A Shared Mechanism of NETosis

in Inflammation

Etty Kruzel-Davila
Lital Remez
Olga Vdovich
Luiza Akria

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567999

Original Research

Published on 24 Mar 2025

Comprehensive multiomics analysis identifies PYCARD as a key pyroptosis-related gene in osteoarthritis synovial macrophages

in Inflammation

Zihao Yao
Yuexin Li
Hanwen Mai
Zhuolun Wang
Haiyan Zhang
Daozhang Cai
Xiangjiang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1558139

369 views

Review

Published on 24 Mar 2025

Methyltransferase-like 3-mediated RNA N6-methyladenosine contributes to immune dysregulation: diagnostic biomarker and therapeutic target

in Inflammation

Deshuang Zhang
Ting Xu
Xiaoxue Gao
Yi Qu
Xiaojuan Su

Frontiers in Immunology

doi 10.3389/fimmu.2025.1523503

197 views

Original Research

Published on 24 Mar 2025

CMTM3 regulates vascular endothelial cell dysfunction by influencing pulmonary vascular endothelial permeability and inflammation in ARDS

in Inflammation

Ziyan Xiao
Gang Zhou
Haiyan Xue
Lihe Chen
Xiujuan Zhao
Shu Li
Chun Fu
Zhengzhou Wang
Fengxue Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1544610

207 views