Frontiers in Immunology | Immunological Tolerance and Regulation

Original Research

Published on 12 Sep 2025

Dexamethasone induced Dectin-1 activation enhances NLRP3 inflammasome activation

in Immunological Tolerance and Regulation

Ruth-Miriam Koerber
Sebastian Oberbeck
Philipp Kotthoff
Solveig N. Daecke
Peter Brossart
Stefanie A. E. Held

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656288

1,155 views

Correction

Accepted on 10 Sep 2025

Recurrent reproductive failure and celiac genetic susceptibility, a leading role of gluten

in Immunological Tolerance and Regulation

Eduardo De La Fuente Munoz
Miguel Fernandez-Arquero
Nabil Subhi-Issa Marin
Kissy Guevara-Hoyer
Lydia Pilar Suarez
Raquel Gil Laborda
Marina Sánchez
Juliana Lucía Ochoa Grullón
María Guzmán Fulgencio
Angela Villegas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1701918

743 views

Original Research

Published on 08 Sep 2025

Decoding neutrophil extracellular traps and key gene drivers in unexplained pregnancy loss

in Immunological Tolerance and Regulation

Hui Ding
Lu Zhang
Wei Yang
Yu Liu
Chao Wang
Li Liu
Cheng Li
Liyuan Pan
Lin Chen
Meimei Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1628337

943 views

Review

Accepted on 05 Sep 2025

Gaps in Maternal-Fetal Interface Rejection Response: Chronic Histiocytic intervillositis

in Immunological Tolerance and Regulation

Xiaoqian Zhang
Zhenya Fang
Xietong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625701

1,434 views

Original Research

Accepted on 04 Sep 2025

Immunological Reference Intervals in Pregnancy: Longitudinal Analysis of Adaptive Lymphocyte Subsets

in Immunological Tolerance and Regulation

Miguel Dias
Catarina Gregório Martins
Mariana Mata
Madalena Barata
Ana Chung
Susana Sarzedas
Élia Fernandes
Cláudia Appleton
Jorge Lima
Luis Miguel Borrego

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634176

1,096 views

Original Research

Published on 04 Sep 2025

Loss of ATG5 impairs CD4+ T cell activation and promotes anti-tumor responses

in Immunological Tolerance and Regulation

Carlos Plaza-Sirvent
Clara Bessen
Alisha W. Bronietzki
Katjana Klages
Marc Schuster
Jochen Huehn
Ingo Schmitz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1284391

904 views

Original Research

Accepted on 01 Sep 2025

Gut Commensal Bacteria-derived polysaccharide sub-micron particles induce antigen-specific, tolerogenic responses

in Immunological Tolerance and Regulation

Rian Harriman
Allen B Tu
Nicolas Radoc
Hamilton Kakwere
Jamal S Lewis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599480

687 views

Review

Published on 01 Sep 2025

Revisiting Tregs in cancer and beyond: immunological control and therapeutic potential

in Immunological Tolerance and Regulation

Lei Zheng
Dan Wu
Hongwei Xie
Hai Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1581093

1,462 views

Review

Published on 01 Sep 2025

Functional interaction between immune checkpoints and lipid metabolism in the development of arteriosclerosis obliterans

in Immunological Tolerance and Regulation

Junyi Zhang
Liyuan Cui
Xinhang Meng
Yujie Luo
Jingmin Ou
Songcun Wang
Mingke Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665454

714 views

Original Research

Published on 28 Aug 2025

Bone marrow-derived extracellular vesicles from multiple myeloma patients promote adaptive immune dysfunction via HLA-G, PD-1, and PD-L1

in Immunological Tolerance and Regulation

Debora Soncini
Danilo Marimpietri
Francesco Ladisa
Francesco Lai
Irma Airoldi
Roberto Gramignoli
Michele Cea
Fabio Morandi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640168

732 views

Original Research

Published on 28 Aug 2025

Novel proteomics biomarkers of recurrent pregnancy loss reflect the dysregulation of immune interactions at the maternal-fetal interface

in Immunological Tolerance and Regulation

Eszter Tóth
Máté Posta
Dániel Györffy
Orsolya Oravecz
Emese Farkas
Andrea Balogh
Claudia Escher
Magdalena Bober
András Szilágyi
Petronella Hupuczi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621168

1,327 views

Review

Published on 27 Aug 2025

Natural antidepressants in neuroimmunomodulation: molecular mechanisms, action targets, and therapeutic potential

in Immunological Tolerance and Regulation

Shimeng Lv
Linghui Kong
Xia Zhong
Ruirui Shang
Yitong Lu
Guangheng Zhang
Haonan Gao
Xin Hou
Guoqiang Li
Xiaowen Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642001

1,172 views

Original Research

Accepted on 25 Aug 2025

Multi-omics analysis identifies erythroid cells as the major population in mouse placentas expressing the MHC class II antigen presentation, chemokine, and antibacterial immune response genes

in Immunological Tolerance and Regulation

Olga Perik-Zavodskaia
Roman Perik-Zavodskii
Saleh Alrhmoun
Kirill Nazarov
Julia Shevchenko
Konstantin Zaitsev
Sergey Vital'evich Sennikov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644983

285 views

Editorial

Published on 25 Aug 2025

Editorial: Genes, cells, and macroenvironments: regulating the immune response in extreme conditions

in Immunological Tolerance and Regulation

Giuseppina Pennesi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1674347

967 views

Original Research

Published on 22 Aug 2025

4-Octyl Itaconate ameliorates diesel exhaust particle-induced oxidative stress in nasal epithelial cells

in Immunological Tolerance and Regulation

Hanna Steppuhn
Katja Hohenberger
Susanne Mittler
Sonja Trump
Christine Carvalho
Manfred Rauh
Andreas B. Wild
Nikolaos G. Papadopoulos
Susetta Finotto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640499

1,138 views

Editorial

Published on 22 Aug 2025

Editorial: Immune plasticity in mixed pattern rheumatic diseases

in Immunological Tolerance and Regulation

Matilde Otero-Losada
Rodolfo Kölliker-Frers
Radjesh Bisoendial
Francisco Capani

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665204

788 views