Frontiers in Immunology | Immunological Tolerance and Regulation

Original Research

Published on 22 Apr 2025

High-resolution transcriptional impact of AIRE: effects of pathogenic variants p.Arg257Ter, p.Cys311Tyr, and polygenic risk variant p.Arg471Cys

in Immunological Tolerance and Regulation

Amund Holte Berger
Bergithe Eikeland Oftedal
Anette Susanne Bøe Wolff
Eystein Sverre Husebye
Per Morten Knappskog
Eirik Bratland
Stefan Johansson

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572789

122 views

Review

Published on 22 Apr 2025

Scientific developments in understanding food allergy prevention, diagnosis, and treatment

in Immunological Tolerance and Regulation

Shirin Karimi Hund
Vanitha Sampath
Xiaoying Zhou
Bryan Thai
Khushi Desai
Kari C. Nadeau

Frontiers in Immunology

doi 10.3389/fimmu.2025.1572283

106 views

Original Research

Accepted on 21 Apr 2025

EV-microRNA Signatures in Pregnant Women with Idiopathic Recurrent Pregnancy Loss: Deciphering MicroRNAome Pathway Networks at Feto-Maternal Interface

in Immunological Tolerance and Regulation

Chitra Bhardwaj
Minakshi Rohilla
Seema Chopra
Anupriya Kaur
Inusha Panigrahi
Priyanka Srivastava

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578738

Original Research

Accepted on 18 Apr 2025

Manuscript for submission at Frontiers in Immunology Research Topic: Maternal-fetal-placental Immune Interactions

in Immunological Tolerance and Regulation

Liseanne J Van 'T Hof
Johanna M Kapsenberg
Jos Drabbels
Lotte Elisabeth Van Der Meeren
Dave Roelen
Michael Eikmans
Marie-Louise P Van Der Hoorn

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575086

214 views

Original Research

Accepted on 16 Apr 2025

Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology

in Immunological Tolerance and Regulation

Xinyao Zhou
Wuqian Wang
Luan Chen
Yingjun Yang
Xing Wei
Jia Zhou
Kuan Sun
Jianjun Zhu
Xiaofang Sun
Shengying Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1542034

Original Research

Published on 16 Apr 2025

The single-cell atlas of short-chain fatty acid receptors in human and mice hearts

in Immunological Tolerance and Regulation

Xiaojun He
Qiang Wang
Qiang Long
Yiming Zhong
Zhaoxi Qi
Yecen Zhang
Lan Chang
Bei Qian
Shixing Huang
Xinming Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1538384

301 views

Original Research

Published on 15 Apr 2025

Helicobacter pylori outer membrane vesicles mediate central tolerance in C57BL/6J mice offspring T cells via maternal-fetal transmission

in Immunological Tolerance and Regulation

Yusen Wei
Lu Zhou
Xiaofei Zhao
Huiqing Qiu
Dailun Hu
Zhongli Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1522842

320 views

Original Research

Accepted on 14 Apr 2025

Th2 predominance and decreased NK cells in patients with hereditary angioedema

in Immunological Tolerance and Regulation

Linda Sundler Björkman
Evelina Elmér
Arne Egesten
Lillemor Skattum

Frontiers in Immunology

doi 10.3389/fimmu.2025.1536128

Original Research

Accepted on 14 Apr 2025

TRIM28 mediates Mettl5 ubiquitination to promotes Th2 polarization

in Immunological Tolerance and Regulation

Pingchang Yang
Beiping Miao
Lihua Mo
Shihan Miao
Xiwen Zhang
Haoyue Zheng
Yixuan Dong
Bailing Xie
Yuanyi Zhang
Yun Liao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1524633

Correction

Accepted on 14 Apr 2025

Corrigendum: Infection of a β-galactosidase-deficient mouse strain with Theiler's murine encephalomyelitis virus reveals limited immunological dysregulations in this lysosomal storage disease

in Immunological Tolerance and Regulation

Rouven Wannemacher
Felix Stegmann
Deborah Eikelberg
Melanie Bühler
Dandan Li
Sayali Kalidas Kohale
Thanaporn Asawapattanakul
Tim Ebbecke
Maire-Kristin Raulf
Wolfgang Baumgärtner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610299

Original Research

Published on 11 Apr 2025

A dominant, pan-DR binding epitope of Der p 1 in house dust mite allergy induces tolerance in HLA-DR4 transgenic mice

in Immunological Tolerance and Regulation

Heather B. Streeter
Lora G. Lucas
Robert M. West
Mamidipudi T. Krishna
David C. Wraith

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569283

323 views

Original Research

Published on 09 Apr 2025

Therapeutic effects of Isaria felina on postmenopausal osteoporosis: modulation of gut microbiota, metabolites, and immune responses

in Immunological Tolerance and Regulation

Xiaoyan Li
Chenhui Xue
Yongming Yang
Lili Zhao
Lixia Chen
Jing Wang
Lei Yan
Zan Meng
Xiaochen Qiao
Sujiao Liang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1508634

392 views

Original Research

Published on 09 Apr 2025

Infection of a β-galactosidase-deficient mouse strain with Theiler’s murine encephalomyelitis virus reveals limited immunological dysregulations in this lysosomal storage disease

in Immunological Tolerance and Regulation

Rouven Wannemacher
Felix Stegmann
Deborah Eikelberg
Melanie Bühler
Dandan Li
Sayali Kalidas Kohale
Thanaporn Asawapattanakul
Tim Ebbecke
Marie-Kristin Raulf
Wolfgang Baumgärtner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1467207

427 views

Original Research

Published on 08 Apr 2025

Identification of Dinaciclib and Ganetespib as anti-inflammatory drugs using a novel HTP screening assay that targets IFNγ-dependent PD-L1

in Immunological Tolerance and Regulation

Shira Hagbi-Levi
Michal Abraham
Lika Gamaev
Inbal Mishaelian
Ophir Hay
Elina Zorde-Khevalevsky
Ori Wald
Hanna Wald
Devorah Olam
Lola Weiss

Frontiers in Immunology

doi 10.3389/fimmu.2025.1502094

315 views

Original Research

Published on 07 Apr 2025

Endometrial immune assessment in patients with a history of previous euploid blastocyst failure

in Immunological Tolerance and Regulation

Jemma Garratt
Baharak Mohammadi
Balsam Al-Hashimi
Elena Linara-Demakakou
Rukma Bhattacharya
Kamal K. Ahuja
Nick Macklon
Mona Rahmati

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547159

464 views

Review

Accepted on 03 Apr 2025

Trends and hotspots on hymenoptera venom immunotherapy: A bibliometric and visualized analysis of research from 2014 to 2024

in Immunological Tolerance and Regulation

Yun Luo
Minxia Guan
Yichuan Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546704