Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Correction

Published on 18 Nov 2025

Correction: Mechanistic insights into IL-1β-mediated progression of tendinopathy

in Cytokines and Soluble Mediators in Immunity

Yuchi Zhang
Jiayue Wang
Fanbo Tang
Runzhi Xian
Huanhuan Zhang
Yanlin Yuan
Guiquan Chen
Guoqiang Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1736822

118 views

Review

Accepted on 17 Nov 2025

Structural and dynamic properties of IL1 receptors

in Cytokines and Soluble Mediators in Immunity

Julia Zhukova
Julia Lopatnikova
Sergey Vital'evich Sennikov

Frontiers in Immunology

Review

Accepted on 17 Nov 2025

The role of interleukin-37 and interleukin-38 in the development and remission of autism spectrum disorder: A comprehensive review of neuroinflammatory mechanisms and potential therapeutic implications

in Cytokines and Soluble Mediators in Immunity

Zakeya Al Rasbi
Hiba Orsud
Sumaya Hasan Zoughbor
Malak Hajar
Abdulla Mahboob
BASSEM SHABAN SADEK

Frontiers in Immunology

Original Research

Published on 17 Nov 2025

SPHK1-mediated M2 macrophage polarization drives TGF-β1-dependent thrombus fibrosis

in Cytokines and Soluble Mediators in Immunity

Xiaoyun Chen
Fajiu Li
Guofeng Ma
Haifeng Qiang
Maohe Chen
Shi Chen
Yedong Huang
Xingyue Lai
Qinghuang Lin
Chaosheng Deng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681485

273 views

Review

Published on 17 Nov 2025

The pivotal role of cytokines in liver disease pathogenesis and therapeutic potential

in Cytokines and Soluble Mediators in Immunity

Li Li
Xuhua Li
Fan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694582

434 views

Review

Accepted on 14 Nov 2025

Interleukin-32: A Pandora's box in human immunodeficiency virus infection

in Cytokines and Soluble Mediators in Immunity

Abualgasim Abdalla
Emad Manni
Tilal Elsaman
Khalid Abosalif
Ayman Alameen
Malik Suliman Mohamed
Hasan Ejaz

Frontiers in Immunology

125 views

Original Research

Accepted on 14 Nov 2025

Serum Profiling of uPA, PAI-1, and suPAR in Systemic Sclerosis: A Preliminary Study on Analytical Aspects and Associations with Microvascular and Fibrotic Manifestations

in Cytokines and Soluble Mediators in Immunity

Filomena Napolitano
Ilaria Mormile
Gabriele Mignogna
Amato De Paulis
Francesca Wanda Rossi
Nunzia Montuori

Frontiers in Immunology

Original Research

Published on 14 Nov 2025

Human spinal enthesis comparative biology of IL-17F and IL-17A reveals greater T-cell IL-17F induction and IL-23 regulation

in Cytokines and Soluble Mediators in Immunity

Nicole McDermott
Ala Altaie
Tom Macleod
Charlie Bridgewood
Peter Loughenbury
Robert Dunsmuir
Almas Khan
Vishal Borse
Abhay Rao
Avneet Manghera

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658325

1,094 views

Editorial

Published on 13 Nov 2025

Editorial: Cytokines, and biomarkers involved in the immunomodulation of pediatric cancers

in Cytokines and Soluble Mediators in Immunity

Alessandro Poggi
Gabriella Pietra
Ignazio Caruana
Francesca Romana Mariotti
Bruno Azzarone

Frontiers in Immunology

doi 10.3389/fimmu.2025.1713006

715 views

Original Research

Accepted on 10 Nov 2025

CXCL9 and CXCL10 support the exacerbated humoral response in recovered COVID-19 patients who developed acute respiratory distress syndrome by promoting plasma cell differentiation, whereas CXCL9 also induces CD40L and CXCR3 upregulation on T helper cells

in Cytokines and Soluble Mediators in Immunity

Romina Quiroga
Sergio Sanhueza
Catalina Sepúlveda
Bárbara Antilef
Camila Muñoz
Camilo Cabrera
Marco Fraga Figueroa
Faryd Llerena
Gonzalo Labarca
Liliana Lamperti

Frontiers in Immunology

Review

Accepted on 07 Nov 2025

Metabolic Crossroads in Insulin Resistance: Exploring Lipid Dysregulation and Inflammation

in Cytokines and Soluble Mediators in Immunity

Saeede Saadati
Rasoul Godini
Anjana Reddy
Helena Teede
Aya Mousa

Frontiers in Immunology

140 views

Original Research

Published on 07 Nov 2025

Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion

in Cytokines and Soluble Mediators in Immunity

Sisi Yan
Xiang Wang
Qiuji Wu
Jinli Ding
Hui Qiu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629370

448 views

Mini Review

Published on 07 Nov 2025

Cytokine networks and therapeutic advances in systemic lupus erythematosus

in Cytokines and Soluble Mediators in Immunity

Zeping Chen
Shupei Liu
Rui Xie
Pan Zhang
Yue Feng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680418

675 views

Original Research

Published on 06 Nov 2025

Interleukin-6 levels and their haplotypes are associated with serological autoantibodies status and clinical activity in rheumatoid arthritis

in Cytokines and Soluble Mediators in Immunity

Ma. Natividad Flores-Castro
Ramcés Falfán-Valencia
Olivia Briceño
Ilse Adriana Gutiérrez-Pérez
Oscar Zaragoza-García
Gloria Pérez-Rubio
Cristina Morales-Martínez
Iris Paola Guzmán-Guzmán

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679644

792 views

Review

Published on 05 Nov 2025

Cytokines in sepsis: a critical review of the literature on systemic inflammation and multiple organ dysfunction

in Cytokines and Soluble Mediators in Immunity

Roberta Vella
Diego Panci
Francesco Carini
Ginevra Malta
Salvatore Vieni
Sabrina David
Giuseppe Davide Albano
Maria Puntarello
Stefania Zerbo
Antonina Argo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682306

1,137 views

Original Research

Published on 04 Nov 2025

AIMing for survival: The impact of the free and total AIM concentration in septic patients

in Cytokines and Soluble Mediators in Immunity

Birte Dyck
Ulrich Bosch dos Santos
Corinna Müller
Hartmuth Nowak
Tim Rahmel
Lars Palmowski
Matthias Unterberg
Alexander Wolf
Alexander von Busch
Andrea Witowski

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685119

520 views