Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Original Research

Published on 02 Dec 2025

Serum profiling of uPA, PAI-1, and suPAR in systemic sclerosis: a preliminary study on analytical aspects and associations with microvascular and fibrotic manifestations

in Cytokines and Soluble Mediators in Immunity

Filomena Napolitano
Ilaria Mormile
Gabriele Mignogna
Amato de Paulis
Francesca Wanda Rossi
Nunzia Montuori

Frontiers in Immunology

doi 10.3389/fimmu.2025.1697785

175 views

Review

Accepted on 01 Dec 2025

The role of interleukins in peripheral nerve injury and the current status of treatment

in Cytokines and Soluble Mediators in Immunity

悦沈
Li Mingzhu
圣博金
子洋喻
倩刘
Huini Yao
Yuxin Jiang
佳晴付
Ningxin Li李

Frontiers in Immunology

Original Research

Accepted on 27 Nov 2025

Persistent Neutrophil Activation Despite Count Normalization Suggests Immune Dysregulation in Exertional Heat Stroke

in Cytokines and Soluble Mediators in Immunity

Jie Liu
Siya Xu
ZHongzhi Tang
Yue Wang

Frontiers in Immunology

Review

Published on 26 Nov 2025

Interleukin-32: a Pandora’s box in human immunodeficiency virus infection

in Cytokines and Soluble Mediators in Immunity

Abualgasim Elgaili Abdalla
Emad Manni
Tilal Elsaman
Khalid Abosalif
Ayman Ali Mohammed Alameen
Malik Suliman Mohamed
Hasan Ejaz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1708955

329 views

Original Research

Accepted on 25 Nov 2025

IL-33-Mediated Mast Cell and Eosinophil Function Requires Isoprenylation

in Cytokines and Soluble Mediators in Immunity

Jason R Burchett
Aditya Kotha
Destiny T davis
Kaitlyn Jackson
Jordan M Dailey
Tania D Maldonado
Tamara T Haque
Zakaria Hussain
John M Ching
Pamela Guerrerio

Frontiers in Immunology

Review

Published on 25 Nov 2025

Metabolic crossroads in insulin resistance: exploring lipid dysregulation and inflammation

in Cytokines and Soluble Mediators in Immunity

Saeede Saadati
Rasoul Godini
Anjana Reddy
Helena Teede
Aya Mousa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1692742

433 views

Original Research

Accepted on 24 Nov 2025

Endocytosis and non-canonical autophagy mediate extracellular histones cytotoxicity in vascular models of sepsis

in Cytokines and Soluble Mediators in Immunity

C Garcés
P Tascón
L Diago Domingo
A J Ibáñez
G Herrera
L R Rodríguez
K Salewskij
Gustav Jonsson
J M Penninger
Federico V Pallardó

Frontiers in Immunology

142 views

Mini Review

Published on 24 Nov 2025

Immunocyte-derived extracellular vesicles in osteoimmunology: mechanisms, disease contexts, and translational prospects

in Cytokines and Soluble Mediators in Immunity

Lixuan Yang
Ning Li
Hao Xu
Jinman Chen
Qianqian Liang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1709048

364 views

Original Research

Accepted on 21 Nov 2025

The Distinct Contribution of Sternotomy to the Systemic Inflammatory Response during Children's Heart Surgery

in Cytokines and Soluble Mediators in Immunity

Joel David Bierer
Julia Paffile
Roger Stanzel
Mark Henderson
John L Sapp
Pantelis Andreou
Jean Sylvia Marshall
David Horne

Frontiers in Immunology

Original Research

Accepted on 19 Nov 2025

IL-10 and IL-2R as Combined Predictors of Intravenous Immunoglobulin Resistance in Kawasaki Disease: A Retrospective Cohort Study

in Cytokines and Soluble Mediators in Immunity

Huiying Wang
Sun Chen
Chun Zhang
Ji-Hong Huang

Frontiers in Immunology

130 views

Perspective

Published on 19 Nov 2025

Regulatory T cell transdifferentiation as a driver of obesity and diabetes

in Cytokines and Soluble Mediators in Immunity

Acelya Yilmazer
Dimitra Maria Zevla
Karsten Kretschmer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698285

317 views

Original Research

Accepted on 18 Nov 2025

Plastic cannulas mitigate arteriovenous fistula stenosis by suppressing the CFB-mediated inflammatory cascade

in Cytokines and Soluble Mediators in Immunity

Dongjuan Zhang
Deyang Kong
Mingming Zhao
Zhanxi Ou
Lu Ma
Ka Qi
Yang Yang

Frontiers in Immunology

Review

Accepted on 18 Nov 2025

Solute Carrier Protein Family: Physiological Functions, Disease Associations, and Therapeutic Potential in Immune-Related Disorders

in Cytokines and Soluble Mediators in Immunity

Peiyan Li
Chen Liu
Yewei Niu
Jiamin Jin
Jinfeng Yang

Frontiers in Immunology

Correction

Published on 18 Nov 2025

Correction: Mechanistic insights into IL-1β-mediated progression of tendinopathy

in Cytokines and Soluble Mediators in Immunity

Yuchi Zhang
Jiayue Wang
Fanbo Tang
Runzhi Xian
Huanhuan Zhang
Yanlin Yuan
Guiquan Chen
Guoqiang Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1736822

385 views

Review

Accepted on 17 Nov 2025

Structural and dynamic properties of IL1 receptors

in Cytokines and Soluble Mediators in Immunity

Julia Zhukova
Julia Lopatnikova
Sergey Vital'evich Sennikov

Frontiers in Immunology

Review

Accepted on 17 Nov 2025

The role of interleukin-37 and interleukin-38 in the development and remission of autism spectrum disorder: A comprehensive review of neuroinflammatory mechanisms and potential therapeutic implications

in Cytokines and Soluble Mediators in Immunity

Zakeya Al Rasbi
Hiba Orsud
Sumaya Hasan Zoughbor
Malak Hajar
Abdulla Mahboob
BASSEM SHABAN SADEK

Frontiers in Immunology