Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Original Research

Accepted on 24 Jan 2025

Elevated levels of IRF1 and CASP1 as pyroptosis-related biomarkers for intestinal epithelial cells in Crohn's disease

in Cytokines and Soluble Mediators in Immunity

Xiaofang Xu
Xiaodan Lv
Ruizhi Zeng
Zhixi Huang
Ziqian 1102078101@qq.com
Bing Han
Guangfu Lin
Jianing Lin
Shiquan Lin
Junhua Fan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551547

Review

Published on 24 Jan 2025

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential

in Cytokines and Soluble Mediators in Immunity

Feiya Sheng
Mi Li
Jia-Mei Yu
Si-Yu Yang
Liang Zou
Guan-Jun Yang
Le-Le Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1533335

109 views

Original Research

Published on 23 Jan 2025

The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis

in Cytokines and Soluble Mediators in Immunity

Tingting Lin
Huimin Wan
Jie Ming
Yifei Liang
Linxin Ran
Jingjing Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1446415

174 views

Original Research

Accepted on 22 Jan 2025

Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study

in Cytokines and Soluble Mediators in Immunity

peipei huang
fan yang
ruirui dong
lijun wen
qiuling zang
dandan song
junshuang guo
yating wang
ruike zhang
zhiping ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528763

Original Research

Accepted on 21 Jan 2025

Candidate Approaches for Predicting Vitiligo Recurrence: An Effective Model and Biomarkers

in Cytokines and Soluble Mediators in Immunity

Binhao Liu
Jiacheng Shen
Bowen Tian
Bin Zhou
Jiachen Gui
Zhimin Li
Yue Zhang
Wenzhi Hu
Qiang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1468665

Original Research

Accepted on 21 Jan 2025

Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8

in Cytokines and Soluble Mediators in Immunity

Jichao Sha
Maolin Yang
Yashu Lei
Liwei Sun
Cuida Meng
Dongdong Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1526081

Original Research

Accepted on 20 Jan 2025

CD38 deficiency results in a defective short-lived transcriptomic response to chronic graft-versus-host disease induction involving purinergic signaling-associated genes and distinct lupus-associated transcriptomic signatures

in Cytokines and Soluble Mediators in Immunity

Mercedes Zubiaur
Laura Carmen Terron-Camero
Fernando Gordillo-Gonzalez
Eduardo Andres-Leon
Alicia Barroso-del Jesús
Luz María Canet-Antequera
Maria Perez Sanchez-Cañete
África Martínez-Blanco
Marilu Dominguez Pantoja
María Botia-Sánchez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1441981

Review

Accepted on 17 Jan 2025

Pathogenic and Therapeutic Roles of Extracellular Vesicles in Sepsis

in Cytokines and Soluble Mediators in Immunity

Benshuai You
Yang Yang
Jing Wei
Chenglin Zhou
Surong Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535427

Original Research

Published on 15 Jan 2025

Caspase-1 activation, IL-1/IL-6 signature and IFNγ-induced chemokines in lungs of COVID-19 patients

in Cytokines and Soluble Mediators in Immunity

Audrey Cambon
Christophe Guervilly
Clémence Delteil
Nicola Potere
Richard Bachelier
Edwige Tellier
Evelyne Abdili
Marine Leprince
Marco Giani
Ildo Polidoro

Frontiers in Immunology

doi 10.3389/fimmu.2024.1493306

248 views

Original Research

Published on 14 Jan 2025

Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis

in Cytokines and Soluble Mediators in Immunity

Leonie Ruths
Jana Hengge
Graciosa Q. Teixeira
Melanie Haffner-Luntzer
Anita Ignatius
Jana Riegger

Frontiers in Immunology

doi 10.3389/fimmu.2024.1470907

148 views

Hypothesis and Theory

Published on 13 Jan 2025

Healthy individuals genetically at-risk for the development of Pemphigus vulgaris or Alopecia areata share disease-like cytokine dysregulation

in Cytokines and Soluble Mediators in Immunity

Rebekah R. Schwartz
Kristina Seiffert-Sinha
Animesh A. Sinha

Frontiers in Immunology

doi 10.3389/fimmu.2024.1500284

174 views

Original Research

Accepted on 10 Jan 2025

Comprehensive Analysis of Pan-Immune Inflammation and All-Cause Mortality in Rheumatoid Arthritis: A Database-Driven Approach，1999-2018

in Cytokines and Soluble Mediators in Immunity

Muradil • Mardan
Huoliang Zheng
Qingyin Xu
Shaokuan Song
Zeyu Lu
Hui Deng
Hao Cai
Qizhu Chen
Bingyi Yang
Kudelaiti • Abuduwufuer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549955

Review

Accepted on 09 Jan 2025

Based on the immune system: the role of the IL-2 family in pancreatic disease

in Cytokines and Soluble Mediators in Immunity

Yu qing Zhu
Zheng Lu
Ke Ning
Zhuo Wang
Jiao Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1480496

Review

Published on 09 Jan 2025

The role and therapeutic targeting of the CCL2/CCR2 signaling axis in inflammatory and fibrotic diseases

in Cytokines and Soluble Mediators in Immunity

Shan Guo
Qi Zhang
Yingjie Guo
Xiaoyan Yin
Peng Zhang
Tao Mao
Zibin Tian
Xiaoyu Li

Frontiers in Immunology

doi 10.3389/fimmu.2024.1497026

320 views

Original Research

Published on 07 Jan 2025

Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inflammatory reactions

in Cytokines and Soluble Mediators in Immunity

Holger Neb
Verena Roth
Jessica Roos
Tom Bauer
Anja Urbschat
Ulrike Heinicke
Carlo Angioni
Dieter Steinhilber
Matthias Piesche
Nerea Ferreirós

Frontiers in Immunology

doi 10.3389/fimmu.2024.1148806

371 views

Case Report

Accepted on 06 Jan 2025

Case Report: Therapeutic Use of Bortezomib in a Patient With Schnitzler Syndrome

in Cytokines and Soluble Mediators in Immunity

Hua Bai
Dongming Zhou
Jinwen Liu
Jie He
ZHOU MIN
Wenyong Fan
Bing Chen
Yong Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520470

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Articles

Elevated levels of IRF1 and CASP1 as pyroptosis-related biomarkers for intestinal epithelial cells in Crohn's disease

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential

The role of CTGF and MFG-E8 in the prognosis assessment of SCAP: a study combining machine learning and nomogram analysis

Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study

Candidate Approaches for Predicting Vitiligo Recurrence: An Effective Model and Biomarkers

Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8

CD38 deficiency results in a defective short-lived transcriptomic response to chronic graft-versus-host disease induction involving purinergic signaling-associated genes and distinct lupus-associated transcriptomic signatures

Pathogenic and Therapeutic Roles of Extracellular Vesicles in Sepsis

Caspase-1 activation, IL-1/IL-6 signature and IFNγ-induced chemokines in lungs of COVID-19 patients

Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis

Healthy individuals genetically at-risk for the development of Pemphigus vulgaris or Alopecia areata share disease-like cytokine dysregulation

Comprehensive Analysis of Pan-Immune Inflammation and All-Cause Mortality in Rheumatoid Arthritis: A Database-Driven Approach，1999-2018

Based on the immune system: the role of the IL-2 family in pancreatic disease

The role and therapeutic targeting of the CCL2/CCR2 signaling axis in inflammatory and fibrotic diseases

Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for systemic inflammatory reactions

Case Report: Therapeutic Use of Bortezomib in a Patient With Schnitzler Syndrome