Frontiers in Immunology | Cancer Immunity and Immunotherapy

Review

Accepted on 22 Apr 2025

The Relationship Between Polycystic Ovary Syndrome and Gynecological Cancers: Neurotransmitter Metabolism Changes and Immune Regulation

in Cancer Immunity and Immunotherapy

Dong Ning Wu
Yue Zhang
Cong-ying Wu
Bo An
Xin Wang
Jin-xia Ni
Min Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578470

Original Research

Accepted on 22 Apr 2025

Veillonella and Streptococcus are associated with aging of the gut microbiota and affect the efficacy of immune checkpoint inhibitors

in Cancer Immunity and Immunotherapy

Yuya Hirasawa
Junya Isobe
Masahiro Hosonuma
Toshiaki Tsurui
Yuta Baba
Eiji Funayama
Kohei Tajima
Masakazu Murayama
Yoichiro Narikawa
Hitoshi Toyoda

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528521

Original Research

Accepted on 22 Apr 2025

Prognostic significance of calcium-related genes in lung adenocarcinoma and the role of TNNC1 in macrophage polarization and erlotinib resistance

in Cancer Immunity and Immunotherapy

Kai Xie
Jian Feng
Zhe Chen
Gaoming Wang
Yu Yao
Xuewen Min
Jing Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1509222

Original Research

Accepted on 22 Apr 2025

Single-Cell Atlas of Endothelial Cells in Atherosclerosis: Identifying C1 CXCL12+ ECs as Key Proliferative Drivers for Immunological Precision Therapeutics in Atherosclerosis

in Cancer Immunity and Immunotherapy

Zhenzhen Zhao
Yujiang Dong
Zhijie Zhao
Xiahou Zhikai
Cong Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569988

Original Research

Accepted on 22 Apr 2025

Translating genetics into tissue: inflammatory cytokine-producing TAMs and PD-L1 tumor expression as poor prognosis factors in cutaneous melanoma

in Cancer Immunity and Immunotherapy

Celia Barrio-Alonso
Alicia Nieto-Valle
Lucía Barandalla-Revilla
José Antonio Avilés-Izquierdo
Verónica Parra-Blanco
Paloma Sánchez-Mateos
Rafael Samaniego

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587545

Review

Published on 22 Apr 2025

The role of macrophage polarization in ovarian cancer: from molecular mechanism to therapeutic potentials

in Cancer Immunity and Immunotherapy

Chenchen Xu
Jiyu Chen
Mi Tan
Qingqing Tan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1543096

118 views

Original Research

Published on 22 Apr 2025

Patient-derived pancreatic tumor bacteria exhibit oncogenic properties and are recognized by MAIT cells in tumor spheroids

in Cancer Immunity and Immunotherapy

Poojabahen Tajpara
Michał Jacek Sobkowiak
Katie Healy
Sabrina Naud
Beate Gündel
Asif Halimi
Zara Ahmad Khan
Giorgio Gabarrini
Sylvie Le Guyader
Gabriela Imreh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1553034

133 views

Review

Published on 22 Apr 2025

From ex vivo to in vitro models: towards a novel approach to investigate the efficacy of immunotherapies on exhausted Vγ9Vδ2 T cells?

in Cancer Immunity and Immunotherapy

Morgane Chauvet
Dorothée Bourges
Emmanuel Scotet

Frontiers in Immunology

doi 10.3389/fimmu.2025.1556982

111 views

Review

Published on 22 Apr 2025

Mechanistic insights into resistance mechanisms to T cell engagers

in Cancer Immunity and Immunotherapy

Linlin Cao
Gabrielle Leclercq-Cohen
Christian Klein
Antonio Sorrentino
Marina Bacac

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583044

Correction

Published on 22 Apr 2025

Corrigendum: Unraveling the enigma of tumor-associated macrophages: challenges, innovations, and the path to therapeutic breakthroughs

in Cancer Immunity and Immunotherapy

Shengwen Shao
Huilai Miao
Wenxue Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606194

Original Research

Published on 22 Apr 2025

Multi-omics identification of a polyamine metabolism related signature for hepatocellular carcinoma and revealing tumor microenvironment characteristics

in Cancer Immunity and Immunotherapy

Yuexi Yu
Huiru Liu
Kaipeng Liu
Meiqi Zhao
Yiyan Zhang
Runci Jiang
Fengmei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570378

Review

Published on 22 Apr 2025

The mechanism of action and therapeutic potential of tumor-associated macrophages in tumor immune evasion

in Cancer Immunity and Immunotherapy

Kehua Wang
Xu Zhang
Aiqin Li
Xia Qiao
Yanan Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545928

Review

Published on 22 Apr 2025

Eph/ephrin-mediated immune modulation: a potential therapeutic target

in Cancer Immunity and Immunotherapy

Konstantinos Giannopoulos
Ioannis Karikis
Chad Byrd
Georgios Sanidas
Nora Wolff
Maria Triantafyllou
Gabriele Simonti
Robinson Vidva
Ioannis Koutroulis
Stamatios Theocharis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539567

141 views

Original Research

Published on 22 Apr 2025

METTL1-driven nucleotide metabolism reprograms the immune microenvironment in hepatocellular carcinoma: a multi-omics approach for prognostic biomarker discovery

in Cancer Immunity and Immunotherapy

Xie Weng
Yangyue Huang
Zhuoya Fu
Xingli Liu
Fuli Xie
Jiale Wang
Qiaohua Zhu
Dayong Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1582203

Review

Published on 22 Apr 2025

Tissue-resident immune cells in cervical cancer: emerging roles and therapeutic implications

in Cancer Immunity and Immunotherapy

Xidie Li
Juan Deng
Xiaoping Liu
Yan Zhou
Tingting Bi
Jingjing Chen
Jinjin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1541950

Original Research

Published on 22 Apr 2025

Comprehensive analysis of plasma cell heterogeneity and immune interactions in multiple myeloma

in Cancer Immunity and Immunotherapy

Shuang Qu
Zhihai Zheng
Xiaoling Guo
Jiaqi Mei
Sicong Jiang
Biyun Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549742