Frontiers in Immunology | Cancer Immunity and Immunotherapy

Systematic Review

Accepted on 07 Mar 2025

Efficacy and Safety of PD-1/PD-L1 Inhibitors as First-Line Treatment for Esophageal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis

in Cancer Immunity and Immunotherapy

Wei Ren
Hanyu Zhang
Yixin Li
Wu Sun
Hexiang Peng
Huangda Guo
Tianjiao Hou
Mengying Wang
Zhendong Hu
Tao Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563300

Original Research

Accepted on 07 Mar 2025

ESCRT may function as a tumor biomarker, transitioning from pan-cancer analysis to validation within Breast cancer

in Cancer Immunity and Immunotherapy

晓睿陈
Xue-ying Tan
Zong-liang Zang
Wei-qing Song
jiangshui yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1531940

Original Research

Accepted on 07 Mar 2025

Unveiling Purine Metabolism Dysregulation Orchestrated Immunosuppression in Advanced Pancreatic cancer and Concentrating on the Central Role of NT5E

in Cancer Immunity and Immunotherapy

Junqian Zhang
Xiaobo Zhang
Ruixin Wu
Changsheng Dong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569088

Review

Accepted on 07 Mar 2025

Molecular biology of the deadliest cancer -glioblastoma: what do we know?

in Cancer Immunity and Immunotherapy

Aly Ismailov
Aldo Spallone
Alexey Belogurov
Alan Herbert
Maria Poptsova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530305

Original Research

Accepted on 07 Mar 2025

Moringa oleifera Leaves Protein induces apoptosis and inhibits the growth of human T lymphocyte leukemia cells through MAPK/AKT signaling and autophagy flux, retarding

in Cancer Immunity and Immunotherapy

Xiaoxue Liu
Hao Yang
Shanna Xie
Xinyu Wang
Yang Tian
Shuang Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546189

Review

Accepted on 07 Mar 2025

Immune Inhibitory Receptor Agonist Therapeutics

in Cancer Immunity and Immunotherapy

Rustin Lovewell
Solomon Langermann
Dallas B. Flies

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566869

Original Research

Published on 07 Mar 2025

Integrative analysis of single-cell and bulk RNA sequencing reveals the oncogenic role of ANXA5 in gastric cancer and its association with drug resistance

in Cancer Immunity and Immunotherapy

Denggang Chen
Peng Zhang
Li Gong
Hailang Wei
Guanghui Yu
Tingting Zhang
Chen Bai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1562395

282 views

Original Research

Published on 07 Mar 2025

Development of a prognostic model for patients with extensive-stage small cell lung cancer undergoing immunotherapy and chemotherapy

in Cancer Immunity and Immunotherapy

Yunbin Gao
Lixia Zhang
Meng Yan
Zongwen Sun
Haibo Zhao
Lujun Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561333

128 views

Original Research

Published on 07 Mar 2025

Immune checkpoint inhibitors and cancer-related cognitive decline: a propensity score matched analysis in active chemotherapy patients

in Cancer Immunity and Immunotherapy

Guangmin Jian
Jiling Zeng
Jun Lu
Weidong Wang
Yongluo Jiang
Tong Huang
Yu Si Niu
Zhoufang Chai
Xin Qi
Nianqi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1540442

119 views

Original Research

Published on 07 Mar 2025

TMED9: a potential therapeutic target and prognostic marker in glioma and its implications across pan-cancer contexts

in Cancer Immunity and Immunotherapy

Benyong Mi
Chaolin Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1558881

148 views

Original Research

Published on 07 Mar 2025

Camrelizumab-based therapies for the treatment of advanced lung cancer: a prospective, open-label, multicenter, observational, real-world study

in Cancer Immunity and Immunotherapy

Dong Zhao
Minghong Bi
Xiaofei Cheng
Shuhong Wang
Huaidong Cheng
Xiaoyang Xia
Huan Chen
Yanbei Zhang
Zhiqiang Hu
Qisheng Cao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1494708

152 views

Original Research

Published on 07 Mar 2025

Association of type 2 diabetes, hypertension, and hyperlipidemia with immune-related adverse events in patients undergoing immune checkpoint inhibitors therapy

in Cancer Immunity and Immunotherapy

Ruidan Li
Xiaoli Mu
Zheran Liu
Rendong Huang
Xingchen Peng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1472197

126 views

Review

Published on 07 Mar 2025

Cell-free DNA: plays an essential role in early diagnosis and immunotherapy of pancreatic cancer

in Cancer Immunity and Immunotherapy

Yi Wen
Gengmin Zhao
Chunhua Dai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546332

143 views

Review

Published on 07 Mar 2025

Exploring effects of gut microbiota on tertiary lymphoid structure formation for tumor immunotherapy

in Cancer Immunity and Immunotherapy

Yuqing Liu
Fan Li
Juanjuan Wang
Rongcun Yang

Frontiers in Immunology

doi 10.3389/fimmu.2024.1518779

210 views

Original Research

Published on 07 Mar 2025

Entinostat, a histone deacetylase inhibitor, enhances CAR-NK cell anti-tumor activity by sustaining CAR expression

in Cancer Immunity and Immunotherapy

Dong-Hyeon Jo
Shelby Kaczmarek
Abrar Ul Haq Khan
Jannat Pervin
Diana M. Clark
Suresh Gadde
Lisheng Wang
Scott McComb
Alissa Visram
Seung-Hwan Lee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1533044

225 views

Review

Accepted on 06 Mar 2025

Role of long non-coding RNAs in the regulation of ferroptosis in tumors

in Cancer Immunity and Immunotherapy

Ying Ju
Yuanhao Lv
Xu Liu
Jing Lu
Yashen Shi
Huimin Guo
Siguang Xu
Jiaqi Tian
Jun Yang
Jiateng Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568567

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Articles

Efficacy and Safety of PD-1/PD-L1 Inhibitors as First-Line Treatment for Esophageal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis

ESCRT may function as a tumor biomarker, transitioning from pan-cancer analysis to validation within Breast cancer

Unveiling Purine Metabolism Dysregulation Orchestrated Immunosuppression in Advanced Pancreatic cancer and Concentrating on the Central Role of NT5E

Molecular biology of the deadliest cancer -glioblastoma: what do we know?

Moringa oleifera Leaves Protein induces apoptosis and inhibits the growth of human T lymphocyte leukemia cells through MAPK/AKT signaling and autophagy flux, retarding

Immune Inhibitory Receptor Agonist Therapeutics

Integrative analysis of single-cell and bulk RNA sequencing reveals the oncogenic role of ANXA5 in gastric cancer and its association with drug resistance

Development of a prognostic model for patients with extensive-stage small cell lung cancer undergoing immunotherapy and chemotherapy

Immune checkpoint inhibitors and cancer-related cognitive decline: a propensity score matched analysis in active chemotherapy patients

TMED9: a potential therapeutic target and prognostic marker in glioma and its implications across pan-cancer contexts

Camrelizumab-based therapies for the treatment of advanced lung cancer: a prospective, open-label, multicenter, observational, real-world study

Association of type 2 diabetes, hypertension, and hyperlipidemia with immune-related adverse events in patients undergoing immune checkpoint inhibitors therapy

Cell-free DNA: plays an essential role in early diagnosis and immunotherapy of pancreatic cancer

Exploring effects of gut microbiota on tertiary lymphoid structure formation for tumor immunotherapy

Entinostat, a histone deacetylase inhibitor, enhances CAR-NK cell anti-tumor activity by sustaining CAR expression

Role of long non-coding RNAs in the regulation of ferroptosis in tumors