Frontiers in Endocrinology | Systems Endocrinology

Original Research

Accepted on 17 Apr 2025

Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury

in Systems Endocrinology

Pengyu Wang
Zhen Sun
Qing Lan
Shuo Zhang
Yan Song
Leiming Yang
Mi Chen
Jianfen Shen
Qi Huang
Youzhi Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1519153

Original Research

Published on 15 Apr 2025

Triglycerides/high-density lipoprotein-cholesterol ratio outperforms traditional lipid indicators in predicting metabolic dysfunction-associated steatotic liver disease among U.S. adults

in Systems Endocrinology

Jin Yuan
Xuequan He
Yan Lu
Xuehua Pu
Lihe Liu
Xuejun Zhang
Jinping Liao
Guiling Li
Ying Luo
Tianwu Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1591241

269 views

Original Research

Published on 15 Apr 2025

Curvilinear relationship between life's crucial 9 and metabolic syndrome in U.S. adults: a cross-sectional study

in Systems Endocrinology

Bo Wang
Chunqi Jiang
Pingping Yu
Zhen Nie
Ning Wang
Xin Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1559413

175 views

Original Research

Published on 15 Apr 2025

Exploring the link between serum uric acid and endometriosis: a cross-sectional analysis utilizing NHANES data from 1999-2006

in Systems Endocrinology

Haiwei Chen
Yuling Chen
Xiaotong Chen
Lixin Tang
Jiaqi Liu
Wen-Jing Shi
Yu-Hua Ou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1536300

219 views

Original Research

Published on 11 Apr 2025

Association between ethylene oxide exposure and serum sex hormone levels measured in a reference sample of the US general population

in Systems Endocrinology

Wenhao Wu
Jingna Wu
Zebin Hou
Qi Yan
Kaixin Qin
Yuan Zhao
Hua Zhang
Yikun Zhu
Junhua He
Jin Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1533516

392 views

Original Research

Accepted on 10 Apr 2025

Pan-Immune-Inflammation Value and Its Association with All-Cause and Cause-Specific Mortality in the General Population: A Nationwide Cohort Study

in Systems Endocrinology

Ye Zhang
Yong Yue
Zhengyu Sun
Pengcheng Li
Xiaoyi Wang
Gang Cheng
Hailin Huang
Zongping Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1534018

Original Research

Published on 08 Apr 2025

Relationship between muscle quality index and urinary incontinence among U.S. population: evidence from NHANES 2011 to 2014

in Systems Endocrinology

Yiwang Hu
Hanyan Xu
Shuying Xie
Chengshui Chen
Xiong Lei

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1533617

203 views

Original Research

Accepted on 07 Apr 2025

Causal relationship between plasma lipidome and rosacea: a Mendelian randomization analysis

in Systems Endocrinology

Xiaoxue Wang
Zexin Zhu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1427656

Original Research

Accepted on 07 Apr 2025

Association between exposure to terpene compounds and risk of metabolic syndrome: exploring the potential mediating role of inflammatory response

in Systems Endocrinology

Jiyu Nie
Zhizhuo Huang
Lin Wen
Haiying Li
Zhengtian Lai
Chuhang Lin
CHUNXIA JING

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1551784

Original Research

Published on 04 Apr 2025

Association of cardiovascular health with COPD (NHANES 2007-2020): mediating potential of lean body mass

in Systems Endocrinology

Ruoyu Gou
Xiaoyu Chang
Danni Dou
Xin Meng
Ling Hou
Lingqin Zhu
Wei Tuo
Guanghua Li

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1539550

288 views

Original Research

Accepted on 31 Mar 2025

Association between dyslipidemia and vitamin D deficiency: A cross-sectional study in Chinese healthy population

in Systems Endocrinology

Bin Li
Jianhong Wang
Jialie Xu
Jianying Xie
Quanyong Liu
Chenxi Yang
Zhengmao Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1450924

Original Research

Published on 28 Mar 2025

Assessment of stress hyperglycemia ratio to predict mortality in critically ill patients with sepsis: a retrospective cohort study from the MIMIC-IV database

in Systems Endocrinology

Dong Xia
Xing Luo
Youfeng Zhu
Jianqiu Zhu
Yingqiu Xie

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1496696

602 views

Original Research

Published on 18 Mar 2025

Association and mediation between circulating inflammatory proteins and skin fibrosis

in Systems Endocrinology

Zirui Zhao
Dongming Lv
Ruixi Zeng
Yanchao Rong
Zhongye Xu
Rong Yin
Zhicheng Hu
Xiaoling Cao
Bing Tang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1416993

854 views

Original Research

Accepted on 10 Mar 2025

Dissecting the bidirectional associations between the progression of gastrointestinal and endocrine diseases

in Systems Endocrinology

Hongyan Liu
Shucheng Si
Hua Zhang
Siyan Zhan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1538603

Original Research

Published on 18 Feb 2025

EndoGene database: reported genetic variants for 5,926 Russian patients diagnosed with endocrine disorders

in Systems Endocrinology

Anton A. Buzdin
Marianna A. Zolotovskaia
Sergey A. Roumiantsev
Aleksandra G. Emelyanova
Olga O. Golounina
Polina A. Pugacheva
Daniil V. Luppov
Anastasia V. Kuzminyh
Arseniya O. Alexeeva
Anna A. Emelianova

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1472754

804 views

Systematic Review

Published on 13 Feb 2025

Diagnostic accuracy of methylated SEPT9 for primary liver cancer: a systematic review and meta-analysis

in Systems Endocrinology

Danwen Jin
Liyong Qian
Jiayao Chen
Ze Yu
Jinliang Dong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1434174

1,417 views