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MINI REVIEW article

Front. Dent. Med
Sec. Oral-Systemic Immunology
Volume 5 - 2024 | doi: 10.3389/fdmed.2024.1509775
This article is part of the Research Topic Modulation of Immune Response in Oral Health: Current Challenges and Future Directions View all 4 articles

Nanosystems for modulation of immune responses in periodontal therapy: A mini-review

Provisionally accepted
Anirudh Acharya Anirudh Acharya 1*Usha Hegde Usha Hegde 2*Swetha Acharya Swetha Acharya 2
  • 1 University of Sharjah, Sharjah, United Arab Emirates
  • 2 JSS Dental College and Hospital, Mysore, Karnataka, India

The final, formatted version of the article will be published soon.

    Periodontitis is one of the most common oral diseases. It is generally treated by nonsurgical and/or surgical therapy with adjunctive approaches for prevention and control. The current understanding of the pathogenesis of periodontitis has unraveled the importance of the inflammatory and immune reactions to combat periodontitis whose etiology is an overlap of microbial, genetic, and environmental factors in a susceptible host. Based on this premise, many therapeutic modalities have been investigated or attempted to resolve this inflammatory disease. Amongst these, nanomedicine has been shown to have therapeutic applications in periodontitis, especially focused on immunomodulation because periodontitis is characterized by over-reactive immune response. This mini-review explores the potential of nanosystems in treating periodontitis by providing an overview of the research efforts in this field of therapeutics. The unique physicochemical and targeting properties of nanosystems seem to be potentially effective platforms for treating periodontitis.

    Keywords: Nanotechnology, Immunomodulation, nanosystems, Nanomedicine, Periodontitis, therapy

    Received: 11 Oct 2024; Accepted: 13 Dec 2024.

    Copyright: © 2024 Acharya, Hegde and Acharya. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Anirudh Acharya, University of Sharjah, Sharjah, United Arab Emirates
    Usha Hegde, JSS Dental College and Hospital, Mysore, Karnataka, India

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.