Frontiers in Chemistry | Chemical Biology

Original Research

Published on 28 Oct 2022

A macrocyclic molecule with multiple antioxidative activities protects the lens from oxidative damage

in Chemical Biology

Jinmin Zhang
Yu Yu
Magy A. Mekhail
Hongli Wu
Kayla N. Green

Frontiers in Chemistry

doi 10.3389/fchem.2022.996604

2,510 views
7 citations

Original Research

Published on 26 Oct 2022

Selective synthesis of α- and β-glycosides of N-acetyl galactosamine using rare earth metal triflates

in Chemical Biology

Jiajia Wang
Wei Zhang
Wei Cao
Kang Liu
Shihao Su
Jing Ma
Xia Li

Frontiers in Chemistry

doi 10.3389/fchem.2022.1029911

2,600 views
3 citations

Editorial

Published on 24 Oct 2022

Editorial: Chemically modified proteins and oligopeptides: A toolbox for therapeutics, diagnostics, and analytics

in Chemical Biology

Sara Pellegrino
Luca Ronda

Frontiers in Chemistry

doi 10.3389/fchem.2022.1054229

1,264 views

Original Research

Published on 24 Oct 2022

Manganese-based Prussian blue nanoparticles inhibit tumor proliferation and migration via the MAPK pathway in pancreatic cancer

in Chemical Biology

Shanshi Tong
Zhilong Yu
Fang Yin
Qilin Yang
Juhang Chu
Luyao Huang
Wenxue Gao
Mingping Qian

Frontiers in Chemistry

doi 10.3389/fchem.2022.1026924

3,710 views
4 citations

Original Research

Published on 19 Oct 2022

An integrated strategy combining metabolomics and machine learning for the evaluation of bioactive markers that differentiate various bile

in Chemical Biology

Xinyue Li
ChenRui Liang
Rui Su
Xiang Wang
Yaqi Yao
Haoran Ding
Guanru Zhou
Zhanglong Luo
Han Zhang
Yubo Li

Frontiers in Chemistry

doi 10.3389/fchem.2022.1005843

2,006 views

Original Research

Published on 17 Oct 2022

The antimicrobial peptide Magainin-2 interacts with BamA impairing folding of E. coli membrane proteins

in Chemical Biology

Angela Di Somma
Carolina Cané
Antonio Moretta
Anna Illiano
Gabriella Pinto
Domenico Cavasso
Angela Amoresano
Luigi Paduano
Angela Duilio

Frontiers in Chemistry

doi 10.3389/fchem.2022.1013788

3,949 views
7 citations

Review

Published on 07 Oct 2022

Light-activated nanomaterials for tumor immunotherapy

in Chemical Biology

Fang Wang
Huijuan Duan
Weizhe Xu
Gang Sheng
Zhaogang Sun
Hongqian Chu

Frontiers in Chemistry

doi 10.3389/fchem.2022.1031811

3,551 views
5 citations

Review

Published on 05 Oct 2022

Druggable targets and therapeutic development for COVID-19

in Chemical Biology

Xiaohua Duan
Lauretta A. Lacko
Shuibing Chen

Frontiers in Chemistry

doi 10.3389/fchem.2022.963701

3,620 views
7 citations

Original Research

Published on 28 Sep 2022

Novel inhibitors and activity-based probes targeting serine proteases

in Chemical Biology

Timothy E. G. Ferguson
James A. Reihill
S. Lorraine Martin
Brian Walker

Frontiers in Chemistry

doi 10.3389/fchem.2022.1006618

3,922 views
3 citations

Review

Published on 27 Sep 2022

Advances in IgA glycosylation and its correlation with diseases

in Chemical Biology

Li Ding
Xiangqin Chen
Hongwei Cheng
Tiantian Zhang
Zheng Li

Frontiers in Chemistry

doi 10.3389/fchem.2022.974854

13,037 views
36 citations

Original Research

Published on 20 Sep 2022

A computational study of the structure and function of human Zrt and Irt-like proteins metal transporters: An elevator-type transport mechanism predicted by AlphaFold2

in Chemical Biology

Andrea Pasquadibisceglie
Adriana Leccese
Fabio Polticelli

Frontiers in Chemistry

doi 10.3389/fchem.2022.1004815

2,518 views
11 citations

Original Research

Published on 20 Sep 2022

Symmetry dual functional pyrimidine-BODIPY probes for imaging targeting and activity study

in Chemical Biology

Shuping Xu
Ying Liu
Zhou Wang
Aolin He
Guofan Jin

Frontiers in Chemistry

doi 10.3389/fchem.2022.977008

1,581 views
1 citation

Original Research

Published on 14 Sep 2022

Synthesis of cholera toxin B subunit glycoconjugates using site-specific orthogonal oxime and sortase ligation reactions

in Chemical Biology

Jonathan P. Dolan
Darren C. Machin
Simone Dedola
Robert A. Field
Michael E. Webb
W. Bruce Turnbull

Frontiers in Chemistry

doi 10.3389/fchem.2022.958272

2,579 views
3 citations

Original Research

Published on 13 Sep 2022

Crystal structure of the α-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer

in Chemical Biology

Yu-Hsuan Hsiao
Szu-Jo Huang
En-Chi Lin
Po-Yun Hsiao
Shu-Ing Toh
I-Hsuan Chen
Zhengren Xu
Yu-Pei Lin
Hsueh-Ju Liu
Chin-Yuan Chang

Frontiers in Chemistry

doi 10.3389/fchem.2022.1001311

2,549 views
4 citations

Original Research

Published on 13 Sep 2022

Synthesis and Biological Evaluation of Termini-Modified and Cyclic Variants of the Connexin43 Inhibitor Peptide5

in Chemical Biology

Sin Hang Crystal Chan
Jarred M. Griffin
Connor A. Clemett
Margaret A. Brimble
Simon J. O’Carroll
Paul W. R. Harris

Frontiers in Chemistry

doi 10.3389/fchem.2022.877618

1,624 views

Mini Review

Published on 09 Sep 2022

Heparanase in cancer progression: Structure, substrate recognition and therapeutic potential

in Chemical Biology

Fengyan Yuan
Yiyuan Yang
Huiqin Zhou
Jing Quan
Chongyang Liu
Yi Wang
Yujing Zhang
Xing Yu

Frontiers in Chemistry

doi 10.3389/fchem.2022.926353

2,876 views
5 citations

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Articles

A macrocyclic molecule with multiple antioxidative activities protects the lens from oxidative damage

Selective synthesis of α- and β-glycosides of N-acetyl galactosamine using rare earth metal triflates

Editorial: Chemically modified proteins and oligopeptides: A toolbox for therapeutics, diagnostics, and analytics

Manganese-based Prussian blue nanoparticles inhibit tumor proliferation and migration via the MAPK pathway in pancreatic cancer

An integrated strategy combining metabolomics and machine learning for the evaluation of bioactive markers that differentiate various bile

The antimicrobial peptide Magainin-2 interacts with BamA impairing folding of E. coli membrane proteins

Light-activated nanomaterials for tumor immunotherapy

Druggable targets and therapeutic development for COVID-19

Novel inhibitors and activity-based probes targeting serine proteases

Advances in IgA glycosylation and its correlation with diseases

A computational study of the structure and function of human Zrt and Irt-like proteins metal transporters: An elevator-type transport mechanism predicted by AlphaFold2

Symmetry dual functional pyrimidine-BODIPY probes for imaging targeting and activity study

Synthesis of cholera toxin B subunit glycoconjugates using site-specific orthogonal oxime and sortase ligation reactions

Crystal structure of the α-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer

Synthesis and Biological Evaluation of Termini-Modified and Cyclic Variants of the Connexin43 Inhibitor Peptide5

Heparanase in cancer progression: Structure, substrate recognition and therapeutic potential