Original Research

Published on 05 Jan 2023

Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases

in Chemical Biology

Alba Ramos-Llorca
Lisse Decraecker
Valérie M. Y. Cacheux
Irena Zeiburlina
Michelle De bruyn
Louise Battut
Carlos Moreno-Cinos
Davide Ceradini
Eric Espinosa
Gilles Dietrich

Frontiers in Chemistry

doi 10.3389/fchem.2022.1089959

3,751 views
4 citations

Original Research

Published on 04 Jan 2023

The cryoEM structure of cytochrome bd from C. glutamicum provides novel insights into structural properties of actinobacterial terminal oxidases

in Chemical Biology

Tamara N. Grund
Yoshiki Kabashima
Tomoichirou Kusumoto
Di Wu
Sonja Welsch
Junshi Sakamoto
Hartmut Michel
Schara Safarian

Frontiers in Chemistry

doi 10.3389/fchem.2022.1085463

2,853 views
4 citations

Original Research

Published on 22 Dec 2022

An in-cluster Sfp-type phosphopantetheinyl transferase instead of the holo-ACP synthase activates the granaticin biosynthesis under natural physiological conditions

in Chemical Biology

Ming-Rong Deng
Sin Yu Chik
Yan Li
Honghui Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2022.1112362

3,251 views

Original Research

Published on 06 Dec 2022

Analyzing the postulated inhibitory effect of Manumycin A on farnesyltransferase

in Chemical Biology

Anna Hagemann
Philipp Klemens Altrogge
Miriam Caroline Alice Kehrenberg
Daniel Diehl
Dominik Jung
Lea Weber
Hagen Sjard Bachmann

Frontiers in Chemistry

doi 10.3389/fchem.2022.967947

3,026 views
2 citations

Original Research

Published on 01 Dec 2022

Isoprenoid alcohols utilization by malaria parasites

in Chemical Biology

Ignasi Bofill Verdaguer
Rodrigo A. C. Sussmann
Verônica Feijoli Santiago
Giuseppe Palmisano
Gabriel Cândido Moura
Juliana Tonini Mesquita
Lydia Fumiko Yamaguchi
Massuo Jorge Kato
Alejandro Miguel Katzin
Marcell Crispim

Frontiers in Chemistry

doi 10.3389/fchem.2022.1035548

2,985 views
4 citations

Review

Published on 01 Dec 2022

Biphenyls in Clusiaceae: Isolation, structure diversity, synthesis and bioactivity

in Chemical Biology

Youyi Wang
Qing Huang
Li Zhang
Changwu Zheng
Hongxi Xu

Frontiers in Chemistry

doi 10.3389/fchem.2022.987009

3,205 views
4 citations

Review

Published on 30 Nov 2022

Nucleobase-modified nucleosides and nucleotides: Applications in biochemistry, synthetic biology, and drug discovery

in Chemical Biology

Anthony Berdis

Frontiers in Chemistry

doi 10.3389/fchem.2022.1051525

6,697 views
8 citations

Original Research

Published on 28 Nov 2022

Pan-cancer analyses reveal multi-omics and clinical characteristics of RIO kinase 2 in cancer

in Chemical Biology

Kexin Li
Jiahua Zou
Haizhao Yan
Yuqing Li
Man-Mei Li
Zhong Liu

Frontiers in Chemistry

doi 10.3389/fchem.2022.1024670

3,184 views
3 citations

Original Research

Published on 28 Nov 2022

Hydrophobic mismatch and sequence specificity compete when transmembrane helix-helix interactions are measured with the TOXCAT assay

in Chemical Biology

Nadja Hellmann
Dirk Schneider

Frontiers in Chemistry

doi 10.3389/fchem.2022.1049310

1,597 views

Mini Review

Published on 25 Nov 2022

Advances in small molecule two-photon fluorescent trackers for lipid droplets in live sample imaging

in Chemical Biology

Dong Joon Lee
Eun Seo Kim
Hyo Won Lee
Hwan Myung Kim

Frontiers in Chemistry

doi 10.3389/fchem.2022.1072143

3,174 views
6 citations

Original Research

Published on 21 Nov 2022

RNA G-quadruplex forming regions from SARS-2, SARS-1 and MERS coronoviruses

in Chemical Biology

Amani Kabbara
Brune Vialet
Julien Marquevielle
Pierre Bonnafous
Cameron D. Mackereth
Samir Amrane

Frontiers in Chemistry

doi 10.3389/fchem.2022.1014663

3,693 views
10 citations

Original Research

Published on 21 Nov 2022

Caulerpa racemosa extract inhibits HeLa cancer cells migration by altering expression of epithelial-mesenchymal transition proteins

in Chemical Biology

Happy Kurnia Permatasari
Ektina Naura Barbara Ulfa
Vanessa Pradna Adyana Daud
Hikmawan Wahyu Sulistomo
Fahrul Nurkolis

Frontiers in Chemistry

doi 10.3389/fchem.2022.1052238

2,466 views
2 citations

Original Research

Published on 17 Nov 2022

KDEON WK-11: A short antipseudomonal peptide with promising potential

in Chemical Biology

Bruno Casciaro
Maria Rosa Loffredo
Floriana Cappiello
Niamh O’Sullivan
Carola Tortora
Rizwan Manzer
Sougata Karmakar
Alan Haskell
Syed K. Hasan
Maria Luisa Mangoni

Frontiers in Chemistry

doi 10.3389/fchem.2022.1000765

1,602 views
5 citations

Original Research

Published on 11 Nov 2022

Phytochemical profiling, in vitro biological activity, docking studies, and cytotoxicity assessments of Rondeletia odorata Jacquin: An unexplored plant of the coffee family

in Chemical Biology

Anjum Khursheed
Saeed Ahmad
Muhammad Saleem
Kashif-ur-Rehman Khan
Jallat Khan
Ilkay Erdogan Orhan
Nurten Abaci
Muhammad Imran
Saba Tauseef
Reaz Uddin

Frontiers in Chemistry

doi 10.3389/fchem.2022.1017577

2,833 views

Editorial

Published on 04 Nov 2022

Editorial: Innovators in chemical biology

in Chemical Biology

John D. Wade
Olivier Renaudet
Matthew A. Coleman

Frontiers in Chemistry

doi 10.3389/fchem.2022.1074759

1,749 views

Original Research

Published on 03 Nov 2022

Natural products, including a new caboxamycin, from Streptomyces and other Actinobacteria isolated in Spain from storm clouds transported by Northern winds of Arctic origin

in Chemical Biology

Aida Sarmiento-Vizcaíno
Jesús Martín
Francisco Javier Ortiz-López
Fernando Reyes
Luis A. García
Gloria Blanco

Frontiers in Chemistry

doi 10.3389/fchem.2022.948795

6,165 views
4 citations

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Articles

Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases

The cryoEM structure of cytochrome bd from C. glutamicum provides novel insights into structural properties of actinobacterial terminal oxidases

An in-cluster Sfp-type phosphopantetheinyl transferase instead of the holo-ACP synthase activates the granaticin biosynthesis under natural physiological conditions

Analyzing the postulated inhibitory effect of Manumycin A on farnesyltransferase

Isoprenoid alcohols utilization by malaria parasites

Biphenyls in Clusiaceae: Isolation, structure diversity, synthesis and bioactivity

Nucleobase-modified nucleosides and nucleotides: Applications in biochemistry, synthetic biology, and drug discovery

Pan-cancer analyses reveal multi-omics and clinical characteristics of RIO kinase 2 in cancer

Hydrophobic mismatch and sequence specificity compete when transmembrane helix-helix interactions are measured with the TOXCAT assay

Advances in small molecule two-photon fluorescent trackers for lipid droplets in live sample imaging

RNA G-quadruplex forming regions from SARS-2, SARS-1 and MERS coronoviruses

Caulerpa racemosa extract inhibits HeLa cancer cells migration by altering expression of epithelial-mesenchymal transition proteins

KDEON WK-11: A short antipseudomonal peptide with promising potential

Phytochemical profiling, in vitro biological activity, docking studies, and cytotoxicity assessments of Rondeletia odorata Jacquin: An unexplored plant of the coffee family

Editorial: Innovators in chemical biology

Natural products, including a new caboxamycin, from Streptomyces and other Actinobacteria isolated in Spain from storm clouds transported by Northern winds of Arctic origin