Frontiers in Cellular and Infection Microbiology | Clinical and Diagnostic Microbiology and Immunology

Original Research

Published on 08 May 2025

Microbiota profiling from biopsied tissues in complex infections: a diagnostic and prognostic analysis through metagenomic next-generation sequencing

in Clinical and Diagnostic Microbiology and Immunology

Tiange Song
Lin Yin
Xiaoli Zhou
Xiaoyan Tao
Dandan Tie
Jie Zhang
Li Jiang

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1567981

1,587 views
2 citations

Original Research

Published on 08 May 2025

Integrated analysis of microbiome and metabolome reveals insights into cervical neoplasia aggravation in a Chinese cohort

in Clinical and Diagnostic Microbiology and Immunology

Qingzhi Zhai
Luyang Zhao
Mingyang Wang
Li Li
Li-an Li
Mingxia Ye
Mingxia Li
Chengfeng Xu
Yuanguang Meng

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1556153

2,734 views

Review

Published on 08 May 2025

Recent progress in tuberculosis diagnosis: insights into blood-based biomarkers and emerging technologies

in Clinical and Diagnostic Microbiology and Immunology

Zewei Yang
Jingjing Li
Jiawen Shen
Huiru Cao
Yuhan Wang
Sensen Hu
Yulu Du
Yange Wang
Zhongyi Yan
Longxiang Xie

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1567592

10,293 views
8 citations

Original Research

Published on 01 May 2025

Application of metagenomic next-generation sequencing in pathogen detection of lung infections

in Clinical and Diagnostic Microbiology and Immunology

Song Chen
Tanglin Ouyang
Kaiyang Wang
Xuan Hou
Rong Zhang
Meiyong Li
Haibin Zhang
Qinghua He
Xiuzhen Li
Zezhang Liu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1513603

5,026 views
1 citation

Original Research

Published on 30 Apr 2025

Emergence and dissemination of multidrug-resistant Klebsiella pneumoniae harboring the novel tmexCD-toprJ RND efflux pump operon

in Clinical and Diagnostic Microbiology and Immunology

Haojin Gao
Bingjie Wang
Meilan Li
Peiyao Zhou
Chunyang Wu
Cailing Wan
Li Shen
Jiana Fu
Weihua Han
Ying Zhou

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1579880

4,493 views
5 citations

Original Research

Published on 30 Apr 2025

Pathogenic bacteria features of central line-associated bloodstream infections in ICU patients: focus on the early predictive value of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios

in Clinical and Diagnostic Microbiology and Immunology

Yuzhen Li
Yanyan Li
Jiqin Wang
Keyu Sun

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1525758

3,021 views
2 citations

Original Research

Published on 28 Apr 2025

Genomic epidemiology of a novel Pandoraea pneumonica group caused severe bloodstream infection in Hainan, China, 2021-2024

in Clinical and Diagnostic Microbiology and Immunology

Chong Chen
Min Wang
Tao Huang
Dong-liang Huang
Shuai Yu
Hui-min Zhao
Xiang-xiang Fu
Xin-xin Li
Hua Wu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1560634

1,967 views

Editorial

Published on 23 Apr 2025

Editorial: Microbiome in an immunocompromised host- a jungle of challenges or a glacier of hidden opportunities?

in Clinical and Diagnostic Microbiology and Immunology

Bartosz Wojciuk
Emilia Liana Falcone
Roland Lawson

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1569842

1,357 views

Original Research

Published on 22 Apr 2025

Investigation of dynamic microbial migration patterns in the respiratory tract

in Clinical and Diagnostic Microbiology and Immunology

Ping Fang
Yanhua Wen
Wenjing Deng
Ruobing Liang
Ping He
Chunya Wang
Na Fan
Kaikai Huo
Kaikai Zhao
Cong Li

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1542562

1,888 views
1 citation

Original Research

Published on 16 Apr 2025

The effects of cyclic peptide [R4W4] in combination with first-line therapy on the survival of Mycobacterium avium

in Clinical and Diagnostic Microbiology and Immunology

Melissa Kelley
Kayvan Sasaninia
Ali Badaoui
Ira Glassman
Arbi Abnousian
Nadia Rai
Rakesh K. Tiwari
Vishwanath Venketaraman

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1547376

2,247 views
2 citations

Original Research

Published on 16 Apr 2025

Aptamer-functionalized graphene quantum dots combined with artificial intelligence detect bacteria for urinary tract infections

in Clinical and Diagnostic Microbiology and Immunology

Kun Li
Shiqiang Fang
Tangwei Wu
Chao Zheng
Yi Zeng
Jinrong He
Yingmiao Zhang
Zhongxin Lu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1555617

2,791 views
3 citations

Mini Review

Published on 10 Apr 2025

A mini review of the pathogenesis of acute rheumatic fever and rheumatic heart disease

in Clinical and Diagnostic Microbiology and Immunology

Shuting Zhuang
Danchun Guo
Dingle Yu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1447149

10,236 views
3 citations

Original Research

Published on 10 Apr 2025

Rapid detection of drug resistance in Mycobacterium tuberculosis clinical isolates for first-line antitubercular drugs by using a novel reporter mycobacteriophage

in Clinical and Diagnostic Microbiology and Immunology

Mingquan Guo
Yan Wang
Juntao Sun
Chengcheng Qian
Douglas B. Lowrie
Liangfei Niu
Juan Wu
Zhidong Hu
Xiao-Yong Fan
Ruiqing Ma

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1589236

2,484 views

Original Research

Published on 10 Apr 2025

Comparative pan-genomic analysis reveals pathogenic mechanisms and genomic plasticity in Vibrio parahaemolyticus clinical and environmental isolates

in Clinical and Diagnostic Microbiology and Immunology

Peng Zhang
Xiaofang Wu
Lei Ji
Wei Yan
Liping Chen
Fenfen Dong

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1574627

2,416 views

Original Research

Published on 08 Apr 2025

A retrospective analysis comparing metagenomic next-generation sequencing with conventional microbiology testing for the identification of pathogens in patients with severe infections

in Clinical and Diagnostic Microbiology and Immunology

Fei Hou
Yanting Qiao
Yuanyuan Qiao
Ya Shi
Mingrui Chen
Min Kong
Xiaohang Hu
Liqing Jiang
Xiaowei Liu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1530486

4,836 views
3 citations

Original Research

Published on 07 Apr 2025

Resistance phenotypes and genomic features of Mycobacterium seoulense isolates

in Clinical and Diagnostic Microbiology and Immunology

Jin Zhao
Xinli Shen
Lulu Jin
Songjun Ji
Xinling Pan

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1553591

1,773 views

Original Research

Published on 07 Apr 2025

Targeted and untargeted metabolomics uncovering the effects of Jiawei Ermiao Granule on patients with persistent HPV infection

in Clinical and Diagnostic Microbiology and Immunology

Xiu Li
Li Ning
Hongting Zhao
Yating Xu
Yu Si
Jiayi Hua
Qingling Ren

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1550908

2,564 views

Original Research

Published on 07 Apr 2025

Identification and characterization of bile microbiota in patients with biliary obstructive diseases using next-generation sequencing of 16S rRNA and ITS

in Clinical and Diagnostic Microbiology and Immunology

Jie Wang
Yu Wang
Jin Cao
Yong Chen
Juan Yu
Ning Sun

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1575824

2,723 views
3 citations

Original Research

Published on 04 Apr 2025

The clinic application of mNGS and ENA-78 assays to identify intra-amniotic infection/inflammation

in Clinical and Diagnostic Microbiology and Immunology

Di Shen
Hui Ju
Hongying Wang
Xietong Wang
Guangzhen Li

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1510671

2,279 views

Original Research

Published on 03 Apr 2025

Metagenomic analysis reveals the diversity of the vaginal virome and its association with vaginitis

in Clinical and Diagnostic Microbiology and Immunology

Xiang Lu
Qiang Lu
Rong Zhu
Mingzhong Sun
Hongmei Chen
Zhihu Ge
Yuchen Jiang
Zhipeng Wang
Lingzhi Zhang
Wen Zhang

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1582553

3,763 views
4 citations

Original Research

Published on 03 Apr 2025

Limitations of human t-lymphotropic virus type 1 antibody testing in hospitals of endemic regions in China

in Clinical and Diagnostic Microbiology and Immunology

Yi Chen
Yanxin Chen
Jing Zheng
Jiajie Yang
Yong Wu
Jianda Hu
Zhengjun Wu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1474526

2,626 views

Review

Published on 01 Apr 2025

Exploring urinary microbiome: insights into neurogenic bladder and improving management of urinary tract infections

in Clinical and Diagnostic Microbiology and Immunology

Jinming Zhang
Yingyun Lei
Huayong Du
Zehui Li
Xiaoxin Wang
Degang Yang
Feng Gao
Jianjun Li

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1512891

5,901 views
5 citations

Original Research

Published on 01 Apr 2025

The diagnostic value of third-generation nanopore sequencing in non-tuberculous mycobacterial infections

in Clinical and Diagnostic Microbiology and Immunology

Chun-Yan Zhao
Chang Song
Yan-Rong Lin
Ying-Xing Nong
Ai-Chun Huang
Shao-Yong Xi
Xiao-Ying Wei
Chun-Mei Zeng
Zhou-Hua Xie
Qing-Dong Zhu

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1557079

1,906 views

Original Research

Published on 28 Mar 2025

Development and validation of an automated and high-throughput quadruplex RT–ddPCR assay for the detection of influenza A, influenza B, respiratory syncytial virus, and SARS-CoV-2

in Clinical and Diagnostic Microbiology and Immunology

Zhongqiang Huang
Jian Song
Chunli Shi
Xiaoyu Fan
Yanqun Xiao
Xueliang Wang

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1529336

3,277 views
4 citations

2,022 articles

articles

Microbiota profiling from biopsied tissues in complex infections: a diagnostic and prognostic analysis through metagenomic next-generation sequencing

Integrated analysis of microbiome and metabolome reveals insights into cervical neoplasia aggravation in a Chinese cohort

Recent progress in tuberculosis diagnosis: insights into blood-based biomarkers and emerging technologies

Application of metagenomic next-generation sequencing in pathogen detection of lung infections

Emergence and dissemination of multidrug-resistant Klebsiella pneumoniae harboring the novel tmexCD-toprJ RND efflux pump operon

Pathogenic bacteria features of central line-associated bloodstream infections in ICU patients: focus on the early predictive value of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios

Genomic epidemiology of a novel Pandoraea pneumonica group caused severe bloodstream infection in Hainan, China, 2021-2024

Editorial: Microbiome in an immunocompromised host- a jungle of challenges or a glacier of hidden opportunities?

Investigation of dynamic microbial migration patterns in the respiratory tract

The effects of cyclic peptide [R4W4] in combination with first-line therapy on the survival of Mycobacterium avium

Aptamer-functionalized graphene quantum dots combined with artificial intelligence detect bacteria for urinary tract infections

A mini review of the pathogenesis of acute rheumatic fever and rheumatic heart disease

Rapid detection of drug resistance in Mycobacterium tuberculosis clinical isolates for first-line antitubercular drugs by using a novel reporter mycobacteriophage

Comparative pan-genomic analysis reveals pathogenic mechanisms and genomic plasticity in Vibrio parahaemolyticus clinical and environmental isolates

A retrospective analysis comparing metagenomic next-generation sequencing with conventional microbiology testing for the identification of pathogens in patients with severe infections

Resistance phenotypes and genomic features of Mycobacterium seoulense isolates

Targeted and untargeted metabolomics uncovering the effects of Jiawei Ermiao Granule on patients with persistent HPV infection

Identification and characterization of bile microbiota in patients with biliary obstructive diseases using next-generation sequencing of 16S rRNA and ITS

The clinic application of mNGS and ENA-78 assays to identify intra-amniotic infection/inflammation

Metagenomic analysis reveals the diversity of the vaginal virome and its association with vaginitis

Limitations of human t-lymphotropic virus type 1 antibody testing in hospitals of endemic regions in China

Exploring urinary microbiome: insights into neurogenic bladder and improving management of urinary tract infections

The diagnostic value of third-generation nanopore sequencing in non-tuberculous mycobacterial infections

Development and validation of an automated and high-throughput quadruplex RT–ddPCR assay for the detection of influenza A, influenza B, respiratory syncytial virus, and SARS-CoV-2