Sensor histidine kinases kdpD and aauS regulate biofilm and virulence in Pseudomonas aeruginosa PA14
- 1Department of Precision Medicine, Graduate School of Basic Medical Science, Institute for Antimicrobial Resistance Research and Therapeutics, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea
- 2Department of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States
A Corrigendum on
Sensor histidine kinases kdpD and aauS regulate biofilm and virulence in Pseudomonas aeruginosa PA14
By Sultan M, Arya R, Chaurasia AK and Kim KK (2023) Front. Cell. Infect. Microbiol. 13:1270667. doi: 10.3389/fcimb.2023.1270667
In the originally published article, a part of Figure 6 has duplication of waxworm image Figure 6C and editing errors in the strain names Figure 6D while making the final high-resolution images.
Figure 6. Confirming the roles of kdpD and aauS in the virulence potential of P. aeruginosa using the G. mellonella infection model. (A) Survival of G. mellonella larvae infected with 10 CFU of WT::pUCP18, ΔkdpD::pUCP18, ΔaauS::pUCP18, ΔkdpD::pUCP18kdpD, and ΔaauS::pUCP18aauS strains. The number of larvae in each group was 10 (n =10). The larvae were injected with 20 µL bacterial solution, and their survival was examined for 72 (h) The control group received 20 µL PBS. (B) The health index of larvae is plotted as an average of each group at multiple time points based on the health scoring index (movement, melaninization, cocoon formation, and survival). (C) An image showing the differential melaninization and death of waxworms infected with different bacterial strains; and (D) Assessment of CFUs recovered on selective media CA after 72 h of infection. The experiments were performed in triplicates. The significance of the data was analyzed using Student’s t-test. P < 0.05 was considered statistically significant (ns, non significant; **p < 0.01, and ***p < 0.005).
Specifically, the worm image in two panels of Figure 6C (PBS control-WT pUCP18 and ΔkdpD::pUCP18-ΔkdpD::pUCP18kdpD) are duplicated. The names of two strains (ΔkdpD::pUCP18kdpD and ΔaauS::pUCP18) in Figure 6D are interchanged. These errors have been corrected as shown in Figures 6C, D below. There is no change in the figure legends. We apologize for any inconvenience this error may have caused. It is noteworthy that these modifications do not change the scientific conclusions of the paper in any way.
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Keywords: Pseudomonas aeruginosa, two-component system (TCS), sensor histidine kinase, KdpD, AauS, quorum sensing (QS), virulence
Citation: Sultan M, Arya R, Chaurasia AK and Kim KK (2024) Corrigendum: Sensor histidine kinases kdpD and aauS regulate biofilm and virulence in Pseudomonas aeruginosa PA14. Front. Cell. Infect. Microbiol. 14:1501233. doi: 10.3389/fcimb.2024.1501233
Received: 24 September 2024; Accepted: 25 September 2024;
Published: 16 October 2024.
Approved by:
Frontiers Editorial Office, Frontiers Media SA, SwitzerlandCopyright © 2024 Sultan, Arya, Chaurasia and Kim. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Rekha Arya, rekhuarya@gmail.com; Akhilesh Kumar Chaurasia, chaurasia.ak@gmail.com; Kyeong Kyu Kim, kyeongkyu@skku.edu