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REVIEW article

Front. Cell. Infect. Microbiol.
Sec. Intestinal Microbiome
Volume 14 - 2024 | doi: 10.3389/fcimb.2024.1291148

Gut Bacteria: An Etiological Agent in Human Pathological Conditions

Provisionally accepted
Md Minarul Islam Md Minarul Islam Seong-Tshool Hong Seong-Tshool Hong *
  • Institute for Medical Science, Medical School, Chonbuk National University, Jeonju, North Jeolla, Republic of Korea

The final, formatted version of the article will be published soon.

    Through complex interactions with the host's immune and physiological systems, gut microbiome bacteria play a critical role as etiological agents in a variety of human diseases, having an impact that extends beyond their mere presence and affects the onset, progression, and severity of the disease. Gaining a comprehensive understanding of these microbial interactions is crucial to improving our understanding of disease pathogenesis and creating tailored treatment methods.Correcting microbial imbalances may open new avenues for disease prevention and treatment approaches, according to preliminary data. The gut microbiota exerts an integral part in the pathogenesis of numerous health conditions, including metabolic, neurological, renal, cardiovascular, and gastrointestinal problems as well as COVID-19, according to recent studies.The crucial significance of the microbiome in disease pathogenesis is highlighted by this role, which is comparable to that of hereditary variables. This review investigates the etiological contributions of the gut microbiome to human diseases, its interactions with the host, and the development of prospective therapeutic approaches. To fully harness the benefits of gut microbiome dynamics for improving human health, future research should address existing methodological challenges and deepen our knowledge of microbial interactions.

    Keywords: Gut Microbiota, probiotic, prebiotic, Metabolites, gut-brain axis

    Received: 08 Sep 2023; Accepted: 12 Aug 2024.

    Copyright: © 2024 Islam and Hong. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Seong-Tshool Hong, Institute for Medical Science, Medical School, Chonbuk National University, Jeonju, 561-756, North Jeolla, Republic of Korea

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.