Frontiers in Cell and Developmental Biology

Original Research

Published on 18 Dec 2025

Inflammation centered muscle signature of sarcopenia from postmenopausal women in Shanghai China

in Stem Cell Research

Yongqian Fan
Shangjin Lin
Ming Ling
Tao Cui
Cong Chen
Fengjian Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1726045

241 views

Original Research

Published on 18 Dec 2025

Osteoprogenitor cells from non-regenerative bone show greater resistance to cellular stress than those from regenerative bone

in Stem Cell Research

Joshua Broussard
Sylvia Culpepper
Tyrel Long
Alexander J. Trostle
Robert J. Tower
Mimi C. Sammarco
Jennifer Simkin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1684670

377 views

Original Research

Published on 18 Dec 2025

Targeted peptide modification of mesenchymal stem cells enhances their therapeutic efficacy in the treatment of idiopathic pulmonary fibrosis

in Stem Cell Research

Zelin Lei
Rui Jia
Yixuan Ren
Yirun Zhao
Yun Wang
Wenqian Cao
Xue Bai
Yali Peng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1710750

356 views

Review

Accepted on 17 Dec 2025

Beyond the canonical niche: how astrocytes carried neurogenic potential into the brain parenchyma

in Stem Cell Research

Marco Fogli
Giulia Nato
Paolo Peretto
Annalisa Buffo
Federico Luzzati

Frontiers in Cell and Developmental Biology

Review

Accepted on 17 Dec 2025

Therapeutic Effects of Mesenchymal stromal cells Transplantation in Animal Models of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis of Emphysema and Lung Inflammation Models

in Stem Cell Research

Yuan Zhao
Shuhui Zhou
Juan Pei
Ying Meng
Zhengyi Zhang

Frontiers in Cell and Developmental Biology

102 views

Original Research

Accepted on 16 Dec 2025

Adiponectin Receptor T-cadherin Emerges as a Novel Regulator of Adipose Stem Cell Quiescence and Adipogenesis

in Stem Cell Research

Veronika Sysoeva
Mikhail Arbatsky
Konstantin Kulebyakin
Pyotr A. Tyurin-Kuzmin
Ekaterina Semina
Polina S Klimovich
Ilya B Brodsky
Daniil D Romashin
Adelina Altyeva
Nikita S Voloshin

Frontiers in Cell and Developmental Biology

348 views

Original Research

Accepted on 16 Dec 2025

Degradable fibrin hydrogels for transplantation of iPSC-derived retinal pigment epithelial cell monolayers

in Stem Cell Research

Alan Marmorstein
Brittni Scruggs
Travis Knudsen
Matthew Hill
Francesca Kopp
Emma Trncic
David Korda
Evan Atherton
Aubrey Berger
Silvia C Finnemann

Frontiers in Cell and Developmental Biology

122 views

Original Research

Accepted on 16 Dec 2025

Activation of FCGR2A enhances the antitumor efficacy of hPSC-derived CAR-M

in Stem Cell Research

Xinzhi Yang
Lu Li
Sijing Zhu
Shengtao Li
Xinlu Wang
Yuling Han
Liuliu Yang

Frontiers in Cell and Developmental Biology

Mini Review

Accepted on 15 Dec 2025

Mesenchymal Stem Cell-Based Therapy for Osteoarthritis: A Systematic Review and Meta-Analysis of Clinical Outcomes and Functional Recovery

in Stem Cell Research

Jincheng Wang
Hao Xue
Mingfei Shi
Renshou Chen

Frontiers in Cell and Developmental Biology

115 views

Original Research

Accepted on 15 Dec 2025

Menstrual Blood-Derived Mesenchymal Stromal Cell Secretome Modulates Macrophage Polarization in a Preconditioning-Dependent Manner

in Stem Cell Research

María de los Ángeles De Pedro
María Pulido
Ana María Marchena
Verónica Álvarez Pérez
Francisco Manuel González-Nuño
Witold Szymanski
Johanna Pörschke
Silke Reinartz
Johannes Graumann
Elke Pogge von Strandmann

Frontiers in Cell and Developmental Biology

Review

Accepted on 15 Dec 2025

Modeling Human Placental Biology: A Review of Organoid Technologies

in Stem Cell Research

Alaijah Bashi
Tyana Joseph
Viviane Schuch
Erica L Johnson

Frontiers in Cell and Developmental Biology

122 views

Review

Accepted on 15 Dec 2025

AI-driven biomaterial design: An intelligent closed loop from reverse design to biological response

in Stem Cell Research

Minglei Liu
Yichuan Zhou
Xiaohan Mei
Zehao Yu
Boyun Guan
Yi Xiao
Shixian Liu
Hao Wang
Yanguo Qin

Frontiers in Cell and Developmental Biology

Review

Accepted on 15 Dec 2025

The Role of Enamel Matrix Derivatives in Periodontal Regeneration Following Tooth Replantation/Transplantation: A Narrative Review of Post-Reperfusion Injury

in Stem Cell Research

Junlin Yang
Shouyin Yi
Xin Yang
Lu Yin
Ming Yuan
Kun Tian

Frontiers in Cell and Developmental Biology

Original Research

Accepted on 12 Dec 2025

Dynamic Crosstalk between Macrophage Subsets and BMSCs via Migrasome-AMPK Axis Shapes Fracture Microenvironment Dynamic crosstalk between Tspan4+ macrophage subsets and MSCs via migrasomes orchestrates fracture repair

in Stem Cell Research

Siyu Zhang
Mengci Wang
Abudurexiti Kutibiding
Dandan Liu
Wen Zhao
Yi Yang

Frontiers in Cell and Developmental Biology

Opinion

Published on 11 Dec 2025

The AI-driven blueprint: decoding intervertebral disc repair mechanisms for intelligent biomaterial design

in Stem Cell Research

Yuanzhen Shi
Yifan Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1751851

448 views

Original Research

Published on 11 Dec 2025

Identification of shared lactylation-related gene signatures between osteoporosis and chronic kidney disease

in Stem Cell Research

Dong Liu
Ying Xia
Hui Wang
Kaiqiang Sun
Shunmin Wang
Yaping Yu
Xiaojie Dai

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1719273

406 views

Review

Published on 11 Dec 2025

Single-cell cloning and its approaches

in Stem Cell Research

Amany E. S. Ammar

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1678157

627 views

Review

Accepted on 10 Dec 2025

Advancements in Mesenchymal Stem Cell Therapy for Chronic Wounds: Challenges, Innovations, and Future Directions

in Stem Cell Research

Yi Tang
Tong Su
BaoChuan Huang
QiHong Xu
QingJiang Chen
SaiQiong Zhang
WuQuan Li

Frontiers in Cell and Developmental Biology

171 views

Review

Published on 10 Dec 2025

Stem cell-based strategies for intervertebral disc regeneration in degenerative microenvironments: challenges and solutions

in Stem Cell Research

Honglin Wang
Aoshuang Xu
Wei Hua
Junling Mao
Jiyao Zhang
Xiaobo Ma
Lin Lu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1719332

539 views

Review

Published on 09 Dec 2025

Decoding dental mesenchymal stem cells diversity: single-cell transcriptomics maps heterogeneity in molar development

in Stem Cell Research

Ruilin Zhang
Leyi Chen
Wanli Xu
Wenan Xu
Buling Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1712688

790 views

Original Research

Accepted on 03 Dec 2025

Preclinical biodistribution and safety evaluation of human iPSC-derived dopaminergic neural progenitor cells for Parkinson's disease

in Stem Cell Research

Ying Huang
Hairuo Wen
Lily Li
Lulu Li
Qianqian Li
Chao Qin
Yiyang Mao
Zhi Lin
Hua Jiang
Frank Zhu

Frontiers in Cell and Developmental Biology

149 views

Editorial

Published on 28 Nov 2025

Editorial: Metabolic regulation of stem cell fate

in Stem Cell Research

Rafael Sênos Demarco
Andrés Caicedo
Ana Caroline P. Gandara

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1746636

465 views

Review

Published on 28 Nov 2025

The impact of cellular senescence on aging skeletal muscle

in Stem Cell Research

Michael Kamal
Ryan Bevington
Amanda Johnson
Gianni Parise

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1719279

956 views

Original Research

Published on 25 Nov 2025

Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes

in Stem Cell Research

Minxia Ke
Hao Wang
Kailun Yang
Meng Ji
Nianmin Qi
Yuehong Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1616235

940 views

1,754 articles

articles

Inflammation centered muscle signature of sarcopenia from postmenopausal women in Shanghai China

Osteoprogenitor cells from non-regenerative bone show greater resistance to cellular stress than those from regenerative bone

Targeted peptide modification of mesenchymal stem cells enhances their therapeutic efficacy in the treatment of idiopathic pulmonary fibrosis

Beyond the canonical niche: how astrocytes carried neurogenic potential into the brain parenchyma

Therapeutic Effects of Mesenchymal stromal cells Transplantation in Animal Models of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis of Emphysema and Lung Inflammation Models

Adiponectin Receptor T-cadherin Emerges as a Novel Regulator of Adipose Stem Cell Quiescence and Adipogenesis

Degradable fibrin hydrogels for transplantation of iPSC-derived retinal pigment epithelial cell monolayers

Activation of FCGR2A enhances the antitumor efficacy of hPSC-derived CAR-M

Mesenchymal Stem Cell-Based Therapy for Osteoarthritis: A Systematic Review and Meta-Analysis of Clinical Outcomes and Functional Recovery

Menstrual Blood-Derived Mesenchymal Stromal Cell Secretome Modulates Macrophage Polarization in a Preconditioning-Dependent Manner

Modeling Human Placental Biology: A Review of Organoid Technologies

AI-driven biomaterial design: An intelligent closed loop from reverse design to biological response

The Role of Enamel Matrix Derivatives in Periodontal Regeneration Following Tooth Replantation/Transplantation: A Narrative Review of Post-Reperfusion Injury

Dynamic Crosstalk between Macrophage Subsets and BMSCs via Migrasome-AMPK Axis Shapes Fracture Microenvironment Dynamic crosstalk between Tspan4+ macrophage subsets and MSCs via migrasomes orchestrates fracture repair

The AI-driven blueprint: decoding intervertebral disc repair mechanisms for intelligent biomaterial design

Identification of shared lactylation-related gene signatures between osteoporosis and chronic kidney disease

Single-cell cloning and its approaches

Advancements in Mesenchymal Stem Cell Therapy for Chronic Wounds: Challenges, Innovations, and Future Directions

Stem cell-based strategies for intervertebral disc regeneration in degenerative microenvironments: challenges and solutions

Decoding dental mesenchymal stem cells diversity: single-cell transcriptomics maps heterogeneity in molar development

Preclinical biodistribution and safety evaluation of human iPSC-derived dopaminergic neural progenitor cells for Parkinson's disease

Editorial: Metabolic regulation of stem cell fate

The impact of cellular senescence on aging skeletal muscle

Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes