Frontiers in Cell and Developmental Biology | Molecular and Cellular Pathology

Original Research

Published on 28 Oct 2022

OMIXCARE: OMICS technologies solved about 33% of the patients with heterogeneous rare neuro-developmental disorders and negative exome sequencing results and identified 13% additional candidate variants

in Molecular and Cellular Pathology

Estelle Colin
Yannis Duffourd
Emilie Tisserant
Raissa Relator
Ange-Line Bruel
Frédéric Tran Mau-Them
Anne-Sophie Denommé-Pichon
Hana Safraou
Julian Delanne
Nolwenn Jean-Marçais

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1021785

4,221 views
14 citations

Original Research

Published on 28 Oct 2022

RETRACTED: Survivin knockdown alleviates pathological hydrostatic pressure-induced bladder smooth muscle cell dysfunction and BOO-induced bladder remodeling via autophagy

in Molecular and Cellular Pathology

Guo Chen
Shuang Chen
Xingpeng Di
Shengyin He
Yugao Liu
Rui Qu
Yi Luo
Yuebai Liu
Luo Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.999547

2,500 views
2 citations

Original Research

Published on 28 Oct 2022

COG4 mutation in Saul-Wilson syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells

in Molecular and Cellular Pathology

Zhi-Jie Xia
Sonal Mahajan
Earnest James Paul Daniel
Bobby G. Ng
Mayank Saraswat
Alexandre Rosa Campos
Rabi Murad
Miao He
Hudson H. Freeze

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.979096

3,347 views

Review

Published on 24 Oct 2022

Heterogeneity and regulation of oligodendrocyte morphology

in Molecular and Cellular Pathology

Yasuyuki Osanai
Reiji Yamazaki
Yoshiaki Shinohara
Nobuhiko Ohno

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1030486

5,606 views
11 citations

Review

Published on 24 Oct 2022

Single-cell and single-nuclei RNA sequencing as powerful tools to decipher cellular heterogeneity and dysregulation in neurodegenerative diseases

in Molecular and Cellular Pathology

Raquel Cuevas-Diaz Duran
Juan Carlos González-Orozco
Iván Velasco
Jia Qian Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.884748

11,855 views
31 citations

Original Research

Published on 24 Oct 2022

Transcriptomic analysis of the human placenta reveals trophoblast dysfunction and augmented Wnt signalling associated with spontaneous preterm birth

in Molecular and Cellular Pathology

Khondoker M. Akram
Neha S. Kulkarni
Abbey Brook
Matthew D. Wyles
Dilly O. C. Anumba

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.987740

5,319 views
6 citations

Original Research

Published on 24 Oct 2022

Generation and characterization of a novel gne Knockout Model in Zebrafish

in Molecular and Cellular Pathology

Hagay Livne
Tom Avital
Shmuel Ruppo
Avi Harazi
Stella Mitrani-Rosenbaum
Alon Daya

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.976111

4,416 views
8 citations

Original Research

Published on 24 Oct 2022

Long-term environmental exposure of darkness induces hyperandrogenism in PCOS via melatonin receptor 1A and aromatase reduction

in Molecular and Cellular Pathology

Weiwei Chu
Shang Li
Xueying Geng
Dongshuang Wang
Junyu Zhai
Gang Lu
Wai-Yee Chan
Zi-Jiang Chen
Yanzhi Du

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.954186

4,329 views
9 citations

Mini Review

Published on 20 Oct 2022

The intracellular cation channel TMEM176B as a dual immunoregulator

in Molecular and Cellular Pathology

Marcelo Hill
Sofía Russo
Daniela Olivera
Mateo Malcuori
Germán Galliussi
Mercedes Segovia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1038429

4,830 views
7 citations

Review

Published on 19 Oct 2022

Mitochondrial dynamics involves molecular and mechanical events in motility, fusion and fission

in Molecular and Cellular Pathology

Adam Green
Tanvir Hossain
David M. Eckmann

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1010232

8,493 views
24 citations

Review

Published on 19 Oct 2022

Pathological implications of metabolic reprogramming and its therapeutic potential in medulloblastoma

in Molecular and Cellular Pathology

Veronica Marabitti
Manuela Giansanti
Francesca De Mitri
Francesca Gatto
Angela Mastronuzzi
Francesca Nazio

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1007641

5,715 views
7 citations

Original Research

Published on 18 Oct 2022

The therapeutic effect of adipose-derived lipoaspirate cells in femoral head necrosis by improving angiogenesis

in Molecular and Cellular Pathology

Weixin Zhang
Cheng Zheng
Tiefeng Yu
Houjian Zhang
Jiaxin Huang
Liyue Chen
Peijian Tong
Gehua Zhen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1014789

2,081 views
6 citations

Original Research

Published on 17 Oct 2022

Human visceral and subcutaneous adipose stem and progenitor cells retain depot-specific adipogenic properties during obesity

in Molecular and Cellular Pathology

Neha Mathur
Mai C. K. Severinsen
Mette E. Jensen
Lars Naver
Maren Schrölkamp
Matthew J. Laye
Matthew J. Watt
Søren Nielsen
Rikke Krogh-Madsen
Bente Klarlund Pedersen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.983899

4,618 views
8 citations

Review

Published on 17 Oct 2022

Roles of follistatin-like protein 3 in human non-tumor pathophysiologies and cancers

in Molecular and Cellular Pathology

Shifeng Tian
Xiaoyi Xu
Xiaohui Yang
Linlin Fan
Yuqi Jiao
Minying Zheng
Shiwu Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.953551

5,103 views
3 citations

Original Research

Published on 17 Oct 2022

Mechanisms of estrogen deficiency-induced osteoporosis based on transcriptome and DNA methylation

in Molecular and Cellular Pathology

Ziying Xu
Zihui Yu
Ming Chen
Mingming Zhang
Ruijing Chen
Haikuan Yu
Yuan Lin
Duanyang Wang
Shang Li
Ling Huang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1011725

3,358 views
6 citations

Review

Published on 14 Oct 2022

Genetic variation in placental insufficiency: What have we learned over time?

in Molecular and Cellular Pathology

Li Qing Wang
Icíar Fernandez-Boyano
Wendy P. Robinson

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2022.1038358

7,922 views
8 citations

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Articles

OMIXCARE: OMICS technologies solved about 33% of the patients with heterogeneous rare neuro-developmental disorders and negative exome sequencing results and identified 13% additional candidate variants

RETRACTED: Survivin knockdown alleviates pathological hydrostatic pressure-induced bladder smooth muscle cell dysfunction and BOO-induced bladder remodeling via autophagy

COG4 mutation in Saul-Wilson syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells

Heterogeneity and regulation of oligodendrocyte morphology

Single-cell and single-nuclei RNA sequencing as powerful tools to decipher cellular heterogeneity and dysregulation in neurodegenerative diseases

Transcriptomic analysis of the human placenta reveals trophoblast dysfunction and augmented Wnt signalling associated with spontaneous preterm birth

Generation and characterization of a novel gne Knockout Model in Zebrafish

Long-term environmental exposure of darkness induces hyperandrogenism in PCOS via melatonin receptor 1A and aromatase reduction

The intracellular cation channel TMEM176B as a dual immunoregulator

Mitochondrial dynamics involves molecular and mechanical events in motility, fusion and fission

Pathological implications of metabolic reprogramming and its therapeutic potential in medulloblastoma

The therapeutic effect of adipose-derived lipoaspirate cells in femoral head necrosis by improving angiogenesis

Human visceral and subcutaneous adipose stem and progenitor cells retain depot-specific adipogenic properties during obesity

Roles of follistatin-like protein 3 in human non-tumor pathophysiologies and cancers

Mechanisms of estrogen deficiency-induced osteoporosis based on transcriptome and DNA methylation

Genetic variation in placental insufficiency: What have we learned over time?