Frontiers in Cell and Developmental Biology

Original Research

Published on 17 Apr 2025

Comprehensive transcriptomic analysis integrating bulk and single-cell RNA-seq with machine learning to identify and validate mitochondrial unfolded protein response biomarkers in patients with ischemic stroke

in Cellular Biochemistry

Lu Zhang
Lei Yue
Peng Jia
Ziqi Cheng
Jiwen Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1582252

255 views

Original Research

Accepted on 14 Apr 2025

rFIP-nha activates macrophages towards a pro-inflammatory phenotype via AIM2 inflammasome modulation

in Cellular Biochemistry

Yusi Liu
Zhen Li
Harry Wichers
Shanna Bastiaan-Net
Tamara Hoppenbrouwers

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1533742

104 views

Original Research

Accepted on 14 Apr 2025

Exploring the role of cell cycle regulation in human mature adipocyte dedifferentiation

in Cellular Biochemistry

Giada Ostinelli
Marie-Frédérique Gauthier
Nathalie Vernoux
Emilie Bernier
Tristan Dubé
Simon Marceau
Stephane Lebel
Marie-Ève Tremblay
Andre Tchernof

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1547836

Original Research

Published on 10 Apr 2025

Metabolomic profiling and biomarker identification for early detection and therapeutic targeting of doxorubicin-induced cardiotoxicity

in Cellular Biochemistry

Jingjing Ding
Xianzhen Feng
Zhongqing Xu
Hong Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1543636

297 views

Review

Accepted on 09 Apr 2025

Protein Misfolding and Mitochondrial Dysfunction in Glaucoma

in Cellular Biochemistry

Arunkumar Venkatesan
Audrey Bernstein

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1595121

183 views

Review

Published on 07 Apr 2025

Integration of MicroRNAs with nanomedicine: tumor targeting and therapeutic approaches

in Cellular Biochemistry

Pelin Telkoparan-Akillilar
Silvia Chichiarelli
Paolo Tucci
Luciano Saso

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1569101

361 views

Review

Accepted on 31 Mar 2025

ANXA5: related mechanisms of osteogenesis and additional biological functions

in Cellular Biochemistry

Ming Jin
Jingrun Zhang
Ge Liu
Yimeng Sun
Xiaowei Wei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1553683

Review

Published on 28 Mar 2025

Unveiling the impact of ERAP1 and ERAP2 on migration, angiogenesis and ER stress response

in Cellular Biochemistry

Irma Saulle
Alessandra Velia Vitalyos
Daniel D’Agate
Mario Clerici
Mara Biasin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564649

421 views

Review

Published on 28 Mar 2025

Lactylation in CNS disorders: mechanisms, cellular function, and disease relevance

in Cellular Biochemistry

Jiaxin Tian
Tongyu Zhang
Ruidan Zhang
Sijia Hao
Jingyu Dong
Yiyan Chen
Jinpeng Zhou
Yang Tian

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566921

601 views

Original Research

Published on 27 Mar 2025

Quantitation of global histone post-translational modifications reveal anti-inflammatory epigenetic mechanisms of liquiritigenin based on the optimized super-SILAC strategy

in Cellular Biochemistry

Ping Liu
Jun Zhang
Jingdan Zhang
Yucheng Yuan
Zhiqing Liu
Sixian Chen
Kaifeng Chen
Li Dong
Zhiyuan Cheng
Yinan Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566567

543 views

Review

Published on 26 Mar 2025

SIRT1 and exercise-induced bone metabolism: a regulatory nexus

in Cellular Biochemistry

Lijie Liu
Jiale Zhang
Runhong Cui
Na Wang
Yun Zhang
Lifei Liu
Xinan Zhang
Qingfeng Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1522821

728 views

Review

Published on 26 Mar 2025

Navigating redox imbalance: the role of oxidative stress in embryonic development and long-term health outcomes

in Cellular Biochemistry

Satya Srirama Karthik Divvela
Marialucia Gallorini
Morris Gellisch
Gaurav Deepak Patel
Luciano Saso
Beate Brand-Saberi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1521336

575 views

Original Research

Published on 24 Mar 2025

Exosome-mediated dual drug delivery of curcumin and methylene blue for enhanced cognitive function and mechanistic elucidation in Alzheimer’s disease therapy

in Cellular Biochemistry

Dongxin Yang
Zhuofen Deng
Hai Zhou
Qingshang Zhang
Xibing Zhang
Jun Gong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1562565

804 views

Review

Published on 10 Mar 2025

Tumor-promoting effect and tumor immunity of SRSFs

in Cellular Biochemistry

Shuai Zhang
Yongxi Zhang
Sijia Feng
Miaomiao Han
Zixi Wang
Dan Qiao
Jiaqi Tian
Lan Wang
Baoshun Du
Zheying Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1527309

580 views

Original Research

Published on 28 Feb 2025

Comprehensive analysis of the effects of P4ha1 and P4ha2 deletion on post-translational modifications of fibrillar collagens in mouse skin

in Cellular Biochemistry

Vivek Sarohi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1527839

878 views

Review

Published on 20 Feb 2025

Molecular puzzle of insulin: structural assembly pathways and their role in diabetes

in Cellular Biochemistry

Edyta Urbaniak
Sara Henry
Maciej Lalowski
Malgorzata Borowiak

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1502469

1,048 views