This article is a correction to:
RIPK3: A New Player in Renal Fibrosis
Ying Shi
Xinming Chen
Chunling Huang
Carol Pollock- 1Department of Nephrology, School of Medicine, Stanford University, Palo Alto, CA, United States
- 2Kolling Institute of Medical Research, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia
A Corrigendum on
RIPK3: A New Player in Renal Fibrosis
by Shi Y, Chen X, Huang C and Pollock C (2020). Front. Cell Dev. Biol. 8:502. doi: 10.3389/fcell.2020.00502
In the original article, there was a mistake in the legend for Figure 1 as published. We neglected to include that Figure 1 was created with BioRender.com. The correct legend appears below.
Figure 1. RIPK3 and TGF-β1. TGF-β1 exhibits its biological function via the canonical Smad/non-Smad pathways or TAK1/necrosome/AKT/ACL signaling to mediate ECM accumulation and fibroblast activation. Necroptosis or RIPK3 facilitates NLRP3 inflammasome assembly, triggers mature IL-1β secretion, and promotes the TGF-β1 transcription via the IL-1β regulated AP-1 and NFκB pathway (Lee et al., 2006). IL-1β, TGF-β, and TLR signaling pathways all activate TAK1 and its regulated inflammatory mediators (Kim and Choi, 2012; Fechtner et al., 2017). RIPK3, Receptor-interacting serine/threonine-protein kinase 3; TGF-β1, transforming growth factor beta-1; TAK1, TGF-β-activated kinase 1; AKT, protein kinase B; ACL, ATP citrate lyase; ECM, extracellular matrix; TLR4, toll-like receptor 4; LPS, lipopolysaccharides; NLRP3, NOD-, LRR- and pyrin domain-containing protein 3; IL-1β, interleukin-1β; AP-1, activator protein 1; NFκB, nuclear factor-kappa B. Created with BioRender.com.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Keywords: RIPK3, receptor interacting serine/threonine-protein kinase 3, renal fibrosis, TGF-β1, necroptosis, dabrafenib
Citation: Shi Y, Chen X, Huang C and Pollock C (2021) Corrigendum: RIPK3: A New Player in Renal Fibrosis. Front. Cell Dev. Biol. 9:699073. doi: 10.3389/fcell.2021.699073
Received: 22 April 2021; Accepted: 18 May 2021;
Published: 09 June 2021.
Edited and reviewed by: Frontiers in Cell and Developmental Biology Editorial Office, Frontiers Media SA, Switzerland
Copyright © 2021 Shi, Chen, Huang and Pollock. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Ying Shi, eXNoaTYxMjUmI3gwMDA0MDtzdGFuZm9yZC5lZHU=; eXNoaTYxMjUmI3gwMDA0MDt1bmkuc3lkbmV5LmVkdS5hdQ==; Carol Pollock, Y2Fyb2wucG9sbG9jayYjeDAwMDQwO3N5ZG5leS5lZHUuYXU=