Frontiers in Cardiovascular Medicine | Cardiovascular Genetics and Systems Medicine

Original Research

Published on 06 Jan 2025

Enhanced fibrotic potential of COL1A1hiNR4A1low fibroblasts in ischemic heart revealed by transcriptional dynamics heterogeneity analysis at both bulk and single-cell levels

in Cardiovascular Genetics and Systems Medicine

Cheng Luo
Baoping Tan
Luoxiang Chu
Liqiang Chen
Xinglong Zhong
Yangyang Jiang
Yuluan Yan
Fanrui Mo
Hong Wang
Fan Yang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1460813

1,239 views

Original Research

Published on 03 Dec 2024

Protective effect of UDCA against IL-11- induced cardiac fibrosis is mediated by TGR5 signalling

in Cardiovascular Genetics and Systems Medicine

B. Reilly-O’Donnell
E. Ferraro
R. Tikhomirov
R. Nunez-Toldra
A. Shchendrygina
L. Patel
Y. Wu
A. L. Mitchell
A. Endo
L. Adorini

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1430772

5,127 views

Case Report

Published on 22 Nov 2024

Case Report: Diagnostic challenges in Fabry disease: misinterpreted obstructive hypertrophic cardiomyopathy and the role of enzyme replacement therapy

in Cardiovascular Genetics and Systems Medicine

Weili Cheng
Mingqiang Ao
Dinghu Xu
Yuqing Zhang
Qin Tao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1479374

839 views
1 citation

Case Report

Published on 13 Nov 2024

Case Report: Allelic and biallelic variants in coagulation factor XI cause factor XI deficiency

in Cardiovascular Genetics and Systems Medicine

Chen Liang
Jie-Yuan Jin
Hai-Hong Shi
Hao-Xian Li
Lin-Lin Chen
Yang-Hui Zhang
Qin Wang
Qiu-Li Li
Rui-Man Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1461899

781 views

Original Research

Published on 25 Oct 2024

Systematic identification of therapeutic targets for coronary artery calcification: an integrated transcriptomic and proteomic Mendelian randomization

in Cardiovascular Genetics and Systems Medicine

Lihong Chen
Xiaoqi Ye
Yan Li
Xingwu Ran

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1419440

1,651 views

Original Research

Published on 24 Oct 2024

Cardiovascular disease risk in patients with elevated LDL-C levels: FH vs. non-FH

in Cardiovascular Genetics and Systems Medicine

Haomin Huang
Lamei Li
Anni Yang
Tao Chen
Ganwei Shi
Feng Li
Luya Wang
Gaojun Cai

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1434392

1,049 views

Original Research

Published on 18 Oct 2024

PD-1/PD-L1 and coronary heart disease: a mendelian randomization study

in Cardiovascular Genetics and Systems Medicine

Liangjia Zeng
Yinglan Liang
Ruoyun Zhou
Wenting Yang
Kexin Chen
Baixin He
Yuqing Qiu
Linglong Liu
Deyang Zhou
Zhaolin Xiao

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1424770

2,182 views

Case Report

Published on 11 Oct 2024

A rare homozygous variant of CHKB induced severe cardiomyopathy and a cardiac conduction disorder: a case report

in Cardiovascular Genetics and Systems Medicine

Siyuan Jing
Lu Liu
Yifei Li
Fuqiang Liu
Yimin Hua
Hongyu Duan

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1469237

1,185 views

Case Report

Published on 01 Oct 2024

Dilated cardiomyopathy due to novel LMNA mutation: a case report

in Cardiovascular Genetics and Systems Medicine

Riddhi Patel
Raj Patel
Ekta Patel
Mehul Patel

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1422151

1,116 views

Original Research

Published on 30 Sep 2024

Polyenylphosphatidylcholine alleviates cardiorenal fibrosis, injury and dysfunction in spontaneously hypertensive rats by regulating Plpp3 signaling

in Cardiovascular Genetics and Systems Medicine

Yongqiao Zhang
Jiayi Ma
Feng Wei
Jiaxin Gong
Li Zhuang
Ningzhi Zhang
Zhaoqiang Cui

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1458173

1,834 views

Case Report

Published on 06 Sep 2024

Case Report: A Chinese child with Barth syndrome caused by a novel TAFAZZIN mutation

in Cardiovascular Genetics and Systems Medicine

Mingxuan Che
Fuhai Li
Yaning Jia
Qingzheng Liu
Jian Hu
Jidong Zhang
Shiguo Liu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1465912

812 views

Original Research

Published on 29 Aug 2024

Exploring the shared biomarkers between cardioembolic stroke and atrial fibrillation by WGCNA and machine learning

in Cardiovascular Genetics and Systems Medicine

Jingxin Zhang
Bingbing Zhang
Tengteng Li
Yibo Li
Qi Zhu
Xiting Wang
Tao Lu

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1375768

2,310 views
1 citation

Original Research

Published on 27 Aug 2024

miR-3529-3p/ABCA1 axis regulates smooth muscle cell homeostasis by enhancing inflammation via JAK2/STAT3 pathway

in Cardiovascular Genetics and Systems Medicine

Tingyu Wang
You Yu
Yinglong Ding
Ziying Yang
Shumin Jiang
Faxiong Gao
Shan Liu
Lianbo Shao
Zhenya Shen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1441123

1,453 views

Correction

Published on 16 Aug 2024

Corrigendum: a novel αB-crystallin R123W variant drives hypertrophic cardiomyopathy by promoting maladaptive calcium-dependent signal transduction

in Cardiovascular Genetics and Systems Medicine

Chun Chou
Gregory L. Martin
Gayani Perera
Junya Awata
Amy Larson
Robert Blanton
Michael T. Chin

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1455263

730 views

Systematic Review

Published on 01 Aug 2024

Association between paraoxonase 1 -108C/T polymorphism and coronary heart disease: an updated meta-analysis

in Cardiovascular Genetics and Systems Medicine

Jiadan Liao
Pengcheng Wang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1339701

857 views
1 citation

Case Report

Published on 25 Jul 2024

Case Report: Patent ductus arteriosus with tuberous sclerosis complex

in Cardiovascular Genetics and Systems Medicine

Tingrui Chen
Xiaoxiao Wu
Yiping Wang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2024.1391775

892 views