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ORIGINAL RESEARCH article

Front. Cardiovasc. Med.
Sec. Cardiovascular Surgery
Volume 11 - 2024 | doi: 10.3389/fcvm.2024.1452820

Predictors of low cardiac output syndrome after combined mitral and tricuspid valve surgery

Provisionally accepted
François Labaste François Labaste 1,2,3*Yoan Lavie-Badie Yoan Lavie-Badie 4Robin Bouchau Robin Bouchau 4Lucie Boyère Lucie Boyère 2Pascale Sanchez-Verlaan Pascale Sanchez-Verlaan 2Hélène Gonzalez Hélène Gonzalez 2Bertrand Marcheix Bertrand Marcheix 5Roxana Botea Roxana Botea 5Fanny Vardon-Bounes Fanny Vardon-Bounes 2Vincent Minville Vincent Minville 2
  • 1 Centre Hospitalier Universitaire de Toulouse, Toulouse, France
  • 2 Département d'Anesthésie-réanimation, Centre Hospitalier Universitaire de Toulouse, Toulouse, France
  • 3 Institut Restore, Université Toulouse III Paul Sabatier, Toulouse, France
  • 4 Service de Cardiologie, Centre Hospitalier Universitaire de Toulouse, Toulouse, France
  • 5 Service de chirurgie cardio-vasculaire, centre hospitalier universitaire, Toulouse, France

The final, formatted version of the article will be published soon.

    Introduction: Low cardiac output syndrome (LCOS) is a common complication in cardiac surgery, and we evaluated the incidence of its early occurrence after mitral and tricuspid combined cardiac surgery and its associated risk factors. Material and method: Retrospective, single institution study. We included 88 consecutive adult patients with severe mitral insufficiency scheduled for elective mitral and tricuspid valve replacement surgery between January 2015 and November 2018. The primary endpoint was the occurrence of LCOS, defined as the need for inotropic support or circulatory assistance after surgery. The secondary endpoint was mortality at 30 days. Results: LCOS occurs in 26 patients (29.5%) and its associated risk factors that appeared in the multivariate analysis were chronic kidney failure (adjusted odd ratio (OR) 3.1 ; 95% [CI] 1.0 – 9.9, p=0.05), preoperative left ventricular heart failure (OR 5.3 ; 95% [CI] 1.3 – 10.9, p=0.002), preoperative right ventricular heart failure (OR 3.6 ; 95% [CI] 1.1 – 11.5, p=0.02), mitral valve replacement (OR 3.9 ; 95% [CI] 1.2 – 12.6, p=0.03). LCOS affected the survival of patients (HR = 5.5 ; 95% [CI] 1.1 – 27.7 p = 0.04). Conclusion: LCOS is a frequent complication after mitral and tricuspid combined surgery and is associated with a poor prognostic.

    Keywords: Mitral regugitation, Mitral surgery, tricuspid surgery, Low Cardiac Output State (LCOS), cardiac surgery

    Received: 21 Jun 2024; Accepted: 05 Sep 2024.

    Copyright: © 2024 Labaste, Lavie-Badie, Bouchau, Boyère, Sanchez-Verlaan, Gonzalez, Marcheix, Botea, Vardon-Bounes and Minville. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: François Labaste, Centre Hospitalier Universitaire de Toulouse, Toulouse, France

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