AUTHOR=Labaste François , Lavie-Badie Yoan , Bouchau Robin , Boyère Lucie , Sanchez-Verlaan Pascale , Gonzalez Hélène , Marcheix Bertrand , Botea Roxana , Vardon-Bounes Fanny , Minville Vincent TITLE=Predictors of low cardiac output syndrome after combined mitral and tricuspid valve surgery JOURNAL=Frontiers in Cardiovascular Medicine VOLUME=11 YEAR=2024 URL=https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2024.1452820 DOI=10.3389/fcvm.2024.1452820 ISSN=2297-055X ABSTRACT=Introduction

Low cardiac output syndrome (LCOS) is a common complication in cardiac surgery, and we evaluated the incidence of its early occurrence after mitral and tricuspid combined cardiac surgery and its associated risk factors.

Material and method

Retrospective, single institution study. We included 88 consecutive adult patients with severe mitral insufficiency scheduled for elective mitral and tricuspid valve replacement surgery between January 2015 and November 2018. The primary endpoint was the occurrence of LCOS, defined as the need for inotropic support or circulatory assistance after surgery. The secondary endpoint was mortality at 30 days.

Results

LCOS occurred in 26 patients (29.5%) of the studied patients and its associated risk factors that appeared in the multivariate analysis were chronic kidney failure [adjusted odds ratio (OR) 3.1; 95% confidence interval (CI) 1.0–9.9, p = 0.05], pre-operative left ventricular heart failure (OR 5.3; 95% CI 1.3–10.9, p = 0.002), pre-operative right ventricular heart failure (OR 3.6; 95% CI 1.1–11.5, p = 0.02), and mitral valve replacement (OR 3.9; 95% CI 1.2–12.6, p = 0.03). LCOS affected the survival of patients (HR = 5.5; 95% CI 1.1–27.7 p = 0.04).

Conclusion

LCOS is a frequent complication after mitral and tricuspid combined surgery and is associated with poor prognosis.