Frontiers in Bioinformatics | Integrative Bioinformatics

Original Research

Published on 28 Mar 2025

Identification of key hub genes in pancreatic ductal adenocarcinoma: an integrative bioinformatics study

in Integrative Bioinformatics

Kankana Bhattacharjee
Avik Sengupta
Rahul Kumar
Aryya Ghosh

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1536783

398 views

Review

Published on 24 Feb 2025

Reliable machine learning models in genomic medicine using conformal prediction

in Integrative Bioinformatics

Christina Papangelou
Konstantinos Kyriakidis
Pantelis Natsiavas
Ioanna Chouvarda
Andigoni Malousi

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1507448

1,090 views

Original Research

Published on 28 Jan 2025

DNA methylation biomarker analysis from low-survival-rate cancers based on genetic functional approaches

in Integrative Bioinformatics

Yi-Hsuan Tsai
Prasenjit Mitra
David Taniar
Tun-Wen Pai

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1523524

682 views

Methods

Published on 23 Jan 2025

A novel lossless encoding algorithm for data compression–genomics data as an exemplar

in Integrative Bioinformatics

Anas Al-okaily
Abdelghani Tbakhi

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1489704

674 views

Original Research

Published on 15 Jan 2025

Developing a ceRNA-based lncRNA-miRNA-mRNA regulatory network to uncover roles in skeletal muscle development

in Integrative Bioinformatics

Wang Wenlun
Yu Chaohang
Huang Yan
Li Wenbin
Zhou Nanqing
Hu Qianmin
Wu Shengcai
Yuan Qing
Yu Shirui
Zhang Feng

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1494717

1,225 views

Brief Research Report

Published on 09 Jan 2025

Detection of reproducible liver cancer specific ligand-receptor signaling in blood

in Integrative Bioinformatics

Aram Safrastyan
Damian Wollny

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1332782

655 views

Editorial

Published on 07 Jan 2025

Editorial: Multi-omics approaches in the study of human disease mechanisms

in Integrative Bioinformatics

Dapeng Wang
Giuseppe Agapito

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1546680

904 views

Technology and Code

Published on 20 Dec 2024

PRONAME: a user-friendly pipeline to process long-read nanopore metabarcoding data by generating high-quality consensus sequences

in Integrative Bioinformatics

Benjamin Dubois
Mathieu Delitte
Salomé Lengrand
Claude Bragard
Anne Legrève
Frédéric Debode

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1483255

2,248 views

Original Research

Published on 04 Oct 2024

Discovery of plasma biomarkers related to blood-brain barrier dysregulation in Alzheimer’s disease

in Integrative Bioinformatics

Yuet Ruh Dan
Keng-Hwee Chiam

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1463001

2,068 views

Editorial

Published on 09 Aug 2024

Editorial: Big data and artificial intelligence for genomics and therapeutics – Proceedings of the 19th Annual Meeting of the MidSouth Computational Biology and Bioinformatics Society (MCBIOS)

in Integrative Bioinformatics

Huixiao Hong
Inimary Toby-Ogundeji
Robert J. Doerksen
Zhaohui Steve Qin

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1470107

897 views

Original Research

Published on 26 Jul 2024

Predictive identification and design of potent inhibitors targeting resistance-inducing candidate genes from E. coli whole-genome sequences

in Integrative Bioinformatics

Abdullahi Tunde Aborode
Neeraj Kumar
Christopher Busayo Olowosoke
Tope Abraham Ibisanmi
Islamiyyah Ayoade
Haruna Isiyaku Umar
Abdullahi Temitope Jamiu
Basit Bolarinwa
Zainab Olapade
Abidemi Ruth Idowu

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1411935

2,655 views
2 citations

Original Research

Published on 15 Jul 2024

CAEM-GBDT: a cancer subtype identifying method using multi-omics data and convolutional autoencoder network

in Integrative Bioinformatics

Jiquan Shen
Xuanhui Guo
Hanwen Bai
Junwei Luo

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1403826

1,098 views
1 citation

Original Research

Published on 19 Jun 2024

A comprehensive multi-omics analysis reveals unique signatures to predict Alzheimer’s disease

in Integrative Bioinformatics

Michael Vacher
Rodrigo Canovas
Simon M. Laws
James D. Doecke

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1390607

2,694 views
4 citations

Original Research

Published on 14 May 2024

Pathway-based analyses of gene expression profiles at low doses of ionizing radiation

in Integrative Bioinformatics

Xihaier Luo
Seyednami Niyakan
Patrick Johnstone
Sean McCorkle
Gilchan Park
Vanessa López-Marrero
Shinjae Yoo
Edward R. Dougherty
Xiaoning Qian
Francis J. Alexander

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1280971

1,390 views
1 citation

Original Research

Published on 16 Apr 2024

PAGER-scFGA: unveiling cell functions and molecular mechanisms in cell trajectories through single-cell functional genomics analysis

in Integrative Bioinformatics

Fengyuan Huang
Robert S. Welner
Jake Y. Chen
Zongliang Yue

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1336135

2,066 views

Original Research

Published on 03 Apr 2024

bootGSEA: a bootstrap and rank aggregation pipeline for multi-study and multi-omics enrichment analyses

in Integrative Bioinformatics

Shamini Hemandhar Kumar
Ines Tapken
Daniela Kuhn
Peter Claus
Klaus Jung

Frontiers in Bioinformatics

doi 10.3389/fbinf.2024.1380928

1,817 views
2 citations