Frontiers in Bioengineering and Biotechnology | Tissue Engineering and Regenerative Medicine

Original Research

Accepted on 24 Jul 2025

Innate immune pathway activation to modulate mesenchymal stromal cell (MSC) interactions with synovium and cartilage

in Tissue Engineering and Regenerative Medicine

Peter Linde
Lyndah Chow
Isabella Sabino
Zoë Josephine Williams
Renata Impastato
Steven Dow
Lynn Pezzanite

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1605148

142 views

Review

Accepted on 23 Jul 2025

From Bench to Bedside: Translating Mesenchymal Stem Cell Therapies Through Preclinical and Clinical Evidence

in Tissue Engineering and Regenerative Medicine

Jai Chand Patel
Meenakshi Shukla
Manish Shukla

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1639439

243 views

Original Research

Published on 23 Jul 2025

3D-printed polycaprolactone combined with cartilage acellular matrix tissue engineered cartilage scaffold manufactured by low-temperature deposition manufacturing

in Tissue Engineering and Regenerative Medicine

Zhen Song
Xulong Zhang
Yihao Xu
Jingyuan Ji
Wei Sun
Fei Fan
Jianjun You
Yuan Pang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1604515

409 views

Review

Published on 23 Jul 2025

Physical cues in biomaterials modulate macrophage polarization for bone regeneration: a review

in Tissue Engineering and Regenerative Medicine

Tianxiao Yang
Zhurun Fang
Jin Zhang
Shengnai Zheng

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1640560

445 views

Original Research

Accepted on 21 Jul 2025

Electrospun textiles from Decellularized Bovine Pericardium and Polyvinyl alcohol (PVA) supporting blood coagulation: Innovative approach in biomaterials for research purposes

in Tissue Engineering and Regenerative Medicine

Luca Di Nunno
Veronica Pagani
Elena Canciani
Gerardina Ruocco
MATTIA SPEDICATI
MARIA TALMON
Luca Fusaro
Dalila Di Francesco
Simona Casarella
Manuela Rizzi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1539759

146 views

Review

Published on 21 Jul 2025

Modern experimental methods for assessing the effectiveness of tissue-engineered products for hyaline cartilage regeneration

in Tissue Engineering and Regenerative Medicine

M. S. Bozhokin
Yu. S. Korneva
S. A. Bozhkova
E. R. Mikhaylova
D. M. Marchenko
B. R. Rakhimov
Y. A. Nashchekina
M. G. Khotin

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1595116

920 views

Original Research

Accepted on 18 Jul 2025

Challenges and limitations in developing of a new maxillary standardized rat alveolar bone defect model to study bone regenerative approaches in oral and maxillofacial surgery

in Tissue Engineering and Regenerative Medicine

Naïma Ahmed Omar
Jéssica Roque
Céline Bergeaut
Laurent Bidault
Amedee Joelle
Didier LETOURNEUR
Jean-Christophe Fricain
Mathilde Fenelon

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1494352

230 views

Original Research

Accepted on 15 Jul 2025

Isolation, Characterization, and Vascular Potential of Porcine Cells in a Three-Dimensional Decellularized Liver Matrix Model

in Tissue Engineering and Regenerative Medicine

Sara Morini
Sandra Melitón Barbancho
Álvaro Blanes Rodríguez
Iris Pla-Palacín
Pilar Sainz-Arnal
Natalia Sanchez-Romero
María Victoria Falceto
Olga Mitjana
Antonio Romero
Marcela Andrea Del Río Nechaevsky

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1625999

322 views

Original Research

Accepted on 15 Jul 2025

Restoration of Tendon Repair Microenvironment by Grapefruit Exosome-Loaded Microneedle System for Tendinopathy Therapy

in Tissue Engineering and Regenerative Medicine

Yuan Zhang
Ruiyang Zhang
Ti Zhang
Yuhao Mu
Talante Juma
Xu Li
Hao Li
Quanyi Guo
Yongping Cao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1615650

218 views

Original Research

Accepted on 15 Jul 2025

Bioadhesive Chitosan Hydrogel with Dynamic Covalent Bonds and Sustained Kartogenin Release for Endogenous Cartilage Regeneration

in Tissue Engineering and Regenerative Medicine

Mingjing Li
Fan Li
Jian Xu
Li Zhu
Jiang Xiang
Chunquan Zhu
Zonghui Dai
Sen Tang
Fucheng Ouyang
Jiawen Yu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1606726

240 views

Original Research

Published on 15 Jul 2025

In vitro and in vivo evaluation of immortalized hepatocyte encapsulated click-microbeads with RGD peptide for treatment of liver failure in male rats

in Tissue Engineering and Regenerative Medicine

Su Yee Win
Pinunta Nittayacharn
Jatupoom Ngernmark
Mongkol Chavalitsarot
Chitinart Thedrattanawong
Khanit Sa-ngiamsuntorn
Suradej Hongeng
Norased Nasongkla

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1629228

689 views

Original Research

Published on 14 Jul 2025

Integration of co-culture conditions and 3D gelatin methacryloyl hydrogels to improve human-induced pluripotent stem cells-derived cardiomyocytes maturation

in Tissue Engineering and Regenerative Medicine

Ilaria Gisone
Monica Boffito
Elisa Persiani
Roberta Pappalardo
Elisa Ceccherini
Andrea Alliaud
Manuela Cabiati
Rossella Laurano
Letizia Guiducci
Chiara Caselli

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1576824

747 views

Review

Published on 14 Jul 2025

Tissue engineering strategies for treating intervertebral disc degeneration

in Tissue Engineering and Regenerative Medicine

Guangshuai Nie
Weiyang Liu
Fanjia Zeng
Jia Hu
Zhen Wang
Zhonglian Huang
Hongjiang Chen
Jun Hu
Jiankun Xu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1582189

590 views

Review

Accepted on 11 Jul 2025

Menstrual Blood-Derived Mesenchymal Stromal Cell Extracellular Vesicles -a Potential Tool for Tissue Regeneration and Disease Detection

in Tissue Engineering and Regenerative Medicine

Raminta Vaiciuleviciute
Jolita Pachaleva
Eiva Bernotiene
Gabija Kugaudaite
Ignas Lebedis
Edvinas Krugly
Ilona Uzieliene

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1643408

164 views

Original Research

Accepted on 11 Jul 2025

Laminin-derived peptide drives the cardiomyogenic potential and cardiac cells functionality

in Tissue Engineering and Regenerative Medicine

Simona Casarella
Federica Ferla
Dalila Di Francesco
Veronica Pagani
Carolina Di Varsavia
Irene Regano
Francesca Boccafoschi

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1629412

171 views

Original Research

Published on 10 Jul 2025

Biological effects of exosomes derived from 2D and 3D culture adipose stem cells on JEC Cell proliferation and migration

in Tissue Engineering and Regenerative Medicine

Yifen Li
Gangwei Wang
Yi Zhang
Tao Xu
Xuefeng Jiang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1541150

826 views