Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 19 Nov 2021

Microdissected Pyramidal Cell Proteomics of Alzheimer Brain Reveals Alterations in Creatine Kinase B-Type, 14-3-3-γ, and Heat Shock Cognate 71

in Cellular and Molecular Mechanisms of Brain-aging

Anna Sandebring-Matton
Michael Axenhus
Nenad Bogdanovic
Bengt Winblad
Sophia Schedin-Weiss
Per Nilsson
Lars O. Tjernberg

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.735334

4,171 views
7 citations

Mini Review

Published on 19 Nov 2021

The Interplay of the Unfolded Protein Response in Neurodegenerative Diseases: A Therapeutic Role of Curcumin

in Cellular and Molecular Mechanisms of Brain-aging

Sitabja Mukherjee
Awdhesh Kumar Mishra
G. D. Ghouse Peer
Sali Abubaker Bagabir
Shafiul Haque
Ramendra Pati Pandey
V. Samuel Raj
Neeraj Jain
Atul Pandey
Santosh Kumar Kar

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.767493

7,667 views
21 citations

Review

Published on 16 Nov 2021

Role of G Protein-Coupled Receptors in Microglial Activation: Implication in Parkinson’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Chao Gu
Yajing Chen
Yan Chen
Chun-Feng Liu
Zengyan Zhu
Mei Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.768156

7,914 views
14 citations

Review

Published on 15 Nov 2021

Brain Pathogenesis and Potential Therapeutic Strategies in Myotonic Dystrophy Type 1

in Cellular and Molecular Mechanisms of Brain-aging

Jie Liu
Zhen-Ni Guo
Xiu-Li Yan
Yi Yang
Shuo Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.755392

8,574 views
12 citations

Original Research

Published on 15 Nov 2021

Glutamate Carboxypeptidase II in Aging Rat Prefrontal Cortex Impairs Working Memory Performance

in Cellular and Molecular Mechanisms of Brain-aging

Dibyadeep Datta
Shannon N. Leslie
Elizabeth Woo
Nishita Amancharla
Ayah Elmansy
Miguel Lepe
Adam P. Mecca
Barbara S. Slusher
Angus C. Nairn
Amy F. T. Arnsten

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.760270

3,951 views
17 citations

Original Research

Published on 15 Nov 2021

Deletion of Oncomodulin Gives Rise to Early Progressive Cochlear Dysfunction in C57 and CBA Mice

in Cellular and Molecular Mechanisms of Brain-aging

Leslie K. Climer
Aubrey J. Hornak
Kaitlin Murtha
Yang Yang
Andrew M. Cox
Preston L. Simpson
Andy Le
Dwayne D. Simmons

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.749729

5,861 views
6 citations

Review

Published on 12 Nov 2021

The Potential Role of miRNAs in Cognitive Frailty

in Cellular and Molecular Mechanisms of Brain-aging

Giulia Carini
Laura Musazzi
Francesco Bolzetta
Alberto Cester
Chiara Fiorentini
Alessandro Ieraci
Stefania Maggi
Maurizio Popoli
Nicola Veronese
Alessandro Barbon

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.763110

5,235 views
17 citations

Review

Published on 05 Nov 2021

Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington’s Disease?

in Cellular and Molecular Mechanisms of Brain-aging

Luisana Villegas
Anne Nørremølle
Kristine Freude
Frederik Vilhardt

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.736734

6,511 views
6 citations

Review

Published on 02 Nov 2021

Demyelination of the Optic Nerve: An Underlying Factor in Glaucoma?

in Cellular and Molecular Mechanisms of Brain-aging

Jingfei Xue
Yingting Zhu
Zhe Liu
Jicheng Lin
Yangjiani Li
Yiqing Li
Yehong Zhuo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.701322

10,535 views
15 citations

Original Research

Published on 01 Nov 2021

Human Cytomegalovirus Immediate Early Protein 2 Protein Causes Cognitive Disorder by Damaging Synaptic Plasticity in Human Cytomegalovirus-UL122-Tg Mice

in Cellular and Molecular Mechanisms of Brain-aging

Zhifei Wang
Wenwen Yu
Lili Liu
Junyun Niu
Xianjuan Zhang
Fulong Nan
Lili Xu
Bin Jiang
Dingxin Ke
Wenhua Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.720582

2,933 views
4 citations

Original Research

Published on 22 Oct 2021

Plasma and CSF Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: A Cross-Sectional and Longitudinal Study

in Cellular and Molecular Mechanisms of Brain-aging

Veria Vacchiano
Andrea Mastrangelo
Corrado Zenesini
Marco Masullo
Corinne Quadalti
Patrizia Avoni
Barbara Polischi
Arianna Cherici
Sabina Capellari
Fabrizio Salvi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.753242

9,583 views
55 citations

Original Research

Published on 18 Oct 2021

Synaptic Release Potentiation at Aging Auditory Ribbon Synapses

in Cellular and Molecular Mechanisms of Brain-aging

Thibault Peineau
Séverin Belleudy
Susanna Pietropaolo
Yohan Bouleau
Didier Dulon

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.756449

5,005 views
25 citations

Editorial

Published on 13 Oct 2021

Editorial: Molecular Mechanisms of Thiol-Based Redox Homeostasis and Signaling in the Brain

in Cellular and Molecular Mechanisms of Brain-aging

Bindu Diana Paul
Milos R. Filipovic

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.771877

2,252 views
4 citations

Hypothesis and Theory

Published on 13 Oct 2021

SIRT6 Through the Brain Evolution, Development, and Aging

in Cellular and Molecular Mechanisms of Brain-aging

Alfredo Garcia-Venzor
Debra Toiber

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.747989

7,318 views
20 citations

Original Research

Published on 12 Oct 2021

Selenomethionine Improves Mitochondrial Function by Upregulating Mitochondrial Selenoprotein in a Model of Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Chen Chen
Yao Chen
Zhong-Hao Zhang
Shi-Zheng Jia
Yu-Bin Chen
Shao-Ling Huang
Xin-Wen Xu
Guo-Li Song

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.750921

5,043 views
16 citations

Review

Published on 01 Oct 2021

Exercise-Induced Benefits for Alzheimer’s Disease by Stimulating Mitophagy and Improving Mitochondrial Function

in Cellular and Molecular Mechanisms of Brain-aging

Jiling Liang
Cenyi Wang
Hu Zhang
Jielun Huang
Juying Xie
Ning Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.755665

12,465 views
45 citations