Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 11 Jan 2022

GABAA Receptors in Astrocytes Are Targets for Commonly Used Intravenous and Inhalational General Anesthetic Drugs

in Cellular and Molecular Mechanisms of Brain-aging

Woosuk Chung
Dian-Shi Wang
Shahin Khodaei
Arsene Pinguelo
Beverley A. Orser

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.802582

5,495 views
10 citations

Original Research

Published on 11 Jan 2022

Tau Knockout and α-Synuclein A53T Synergy Modulated Parvalbumin-Positive Neurons Degeneration Staging in Substantia Nigra Pars Reticulata of Parkinson’s Disease-Liked Model

in Cellular and Molecular Mechanisms of Brain-aging

Meige Zheng
Yanchang Liu
Zhaoming Xiao
Luyan Jiao
Xian Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.784665

3,444 views
4 citations

Original Research

Published on 06 Jan 2022

Selective and Inverse U-Shaped Curve Alteration of the Retinal Nerve in Amyotrophic Lateral Sclerosis: A Potential Mirror of the Disease

in Cellular and Molecular Mechanisms of Brain-aging

Yixuan Zhang
Xiangyi Liu
Jiayu Fu
Yuanjin Zhang
Xue Yang
Shuo Zhang
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.783431

2,453 views
7 citations

Review

Published on 05 Jan 2022

Aged Microglia in Neurodegenerative Diseases: Microglia Lifespan and Culture Methods

in Cellular and Molecular Mechanisms of Brain-aging

Hyun-Jung Yoo
Min-Soo Kwon

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.766267

16,307 views
43 citations

Review

Published on 04 Jan 2022

Retrotransposons as a Source of DNA Damage in Neurodegeneration

in Cellular and Molecular Mechanisms of Brain-aging

Eugenie Peze-Heidsieck
Tom Bonnifet
Rania Znaidi
Camille Ravel-Godreuil
Olivia Massiani-Beaudoin
Rajiv L. Joshi
Julia Fuchs

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.786897

10,170 views
23 citations

Original Research

Published on 03 Jan 2022

MRI Volumetric Analysis of the Thalamus and Hypothalamus in Amyotrophic Lateral Sclerosis

in Cellular and Molecular Mechanisms of Brain-aging

Shan Ye
Yishan Luo
Pingping Jin
Yajun Wang
Nan Zhang
Gan Zhang
Lu Chen
Lin Shi
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.610332

4,433 views
7 citations

Original Research

Published on 23 Dec 2021

Effects of Aging on the Structure and Expression of NMDA Receptors of Somatostatin Expressing Neurons in the Mouse Hippocampus

in Cellular and Molecular Mechanisms of Brain-aging

Yaiza Gramuntell
Patrycja Klimczak
Simona Coviello
Marta Perez-Rando
Juan Nacher

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.782737

5,009 views
16 citations

Correction

Published on 20 Dec 2021

Corrigendum: Selenomethionine Improves Mitochondrial Function by Upregulating Mitochondrial Selenoprotein in a Model of Alzheimer's Disease

in Cellular and Molecular Mechanisms of Brain-aging

Chen Chen
Yao Chen
Zhong-Hao Zhang
Shi-Zheng Jia
Yu-Bin Chen
Shao-Ling Huang
Xin-Wen Xu
Guo-Li Song

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.815251

2,532 views

Original Research

Published on 17 Dec 2021

Manipulations of Glutathione Metabolism Modulate IP3-Mediated Store-Operated Ca2+ Entry on Astroglioma Cell Line

in Cellular and Molecular Mechanisms of Brain-aging

Nawfel Mokrane
Yassin Snabi
Thierry Cens
Janique Guiramand
Pierre Charnet
Anaïs Bertaud
Claudine Menard
Matthieu Rousset
Marie-Céleste de Jesus Ferreira
Jean-Baptiste Thibaud

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.785727

3,059 views
7 citations

Review

Published on 16 Dec 2021

Diagnostic and Therapeutic Potential of Exosomes in Neurodegenerative Diseases

in Cellular and Molecular Mechanisms of Brain-aging

Panyue Gao
Xinrong Li
Xinzhe Du
Sha Liu
Yong Xu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.790863

9,529 views
31 citations

Original Research

Published on 15 Dec 2021

Flavones 7,8-DHF, Quercetin, and Apigenin Against Tau Toxicity via Activation of TRKB Signaling in ΔK280 TauRD-DsRed SH-SY5Y Cells

in Cellular and Molecular Mechanisms of Brain-aging

Ni-Ni Chiang
Te-Hsien Lin
Yu-Shan Teng
Ying-Chieh Sun
Kuo-Hsuan Chang
Chung-Yin Lin
Hsiu Mei Hsieh-Li
Ming-Tsan Su
Chiung-Mei Chen
Guey-Jen Lee-Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.758895

7,001 views
26 citations

Review

Published on 09 Dec 2021

Recent Advances in Basic Research for CSF1R-Microglial Encephalopathy

in Cellular and Molecular Mechanisms of Brain-aging

Yan-Li Wang
Fang-Ze Wang
Runzhi Li
Jiwei Jiang
Xiangrong Liu
Jun Xu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.792840

6,843 views
10 citations

Methods

Published on 09 Dec 2021

Making the Best Out of IT: Design and Development of Exergames for Older Adults With Mild Neurocognitive Disorder – A Methodological Paper

in Cellular and Molecular Mechanisms of Brain-aging

Patrick Manser
Eling D. de Bruin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.734012

6,504 views
23 citations

Review

Published on 06 Dec 2021

An Update on Antioxidative Stress Therapy Research for Early Brain Injury After Subarachnoid Hemorrhage

in Cellular and Molecular Mechanisms of Brain-aging

Fa Lin
Runting Li
Wen-Jun Tu
Yu Chen
Ke Wang
Xiaolin Chen
Jizong Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.772036

4,719 views
25 citations

Original Research

Published on 01 Dec 2021

Senescence in Primary Rat Astrocytes Induces Loss of the Mitochondrial Membrane Potential and Alters Mitochondrial Dynamics in Cortical Neurons

in Cellular and Molecular Mechanisms of Brain-aging

Sandra Lizbeth Morales-Rosales
Roberto Santín-Márquez
Pedro Posadas-Rodriguez
Ruth Rincon-Heredia
Teresa Montiel
Raúl Librado-Osorio
Armando Luna-López
Nadia Alejandra Rivero-Segura
Claudio Torres
Agustina Cano-Martínez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.766306

7,172 views
13 citations

Original Research

Published on 26 Nov 2021

Severe Hypoglycemia Contributing to Cognitive Dysfunction in Diabetic Mice Is Associated With Pericyte and Blood–Brain Barrier Dysfunction

in Cellular and Molecular Mechanisms of Brain-aging

Lu Lin
Yubin Wu
Zhou Chen
Lishan Huang
Lijing Wang
Libin Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.775244

6,524 views
21 citations

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Articles

GABAA Receptors in Astrocytes Are Targets for Commonly Used Intravenous and Inhalational General Anesthetic Drugs

Tau Knockout and α-Synuclein A53T Synergy Modulated Parvalbumin-Positive Neurons Degeneration Staging in Substantia Nigra Pars Reticulata of Parkinson’s Disease-Liked Model

Selective and Inverse U-Shaped Curve Alteration of the Retinal Nerve in Amyotrophic Lateral Sclerosis: A Potential Mirror of the Disease

Aged Microglia in Neurodegenerative Diseases: Microglia Lifespan and Culture Methods

Retrotransposons as a Source of DNA Damage in Neurodegeneration

MRI Volumetric Analysis of the Thalamus and Hypothalamus in Amyotrophic Lateral Sclerosis

Effects of Aging on the Structure and Expression of NMDA Receptors of Somatostatin Expressing Neurons in the Mouse Hippocampus

Corrigendum: Selenomethionine Improves Mitochondrial Function by Upregulating Mitochondrial Selenoprotein in a Model of Alzheimer's Disease

Manipulations of Glutathione Metabolism Modulate IP3-Mediated Store-Operated Ca2+ Entry on Astroglioma Cell Line

Diagnostic and Therapeutic Potential of Exosomes in Neurodegenerative Diseases

Flavones 7,8-DHF, Quercetin, and Apigenin Against Tau Toxicity via Activation of TRKB Signaling in ΔK280 TauRD-DsRed SH-SY5Y Cells

Recent Advances in Basic Research for CSF1R-Microglial Encephalopathy

Making the Best Out of IT: Design and Development of Exergames for Older Adults With Mild Neurocognitive Disorder – A Methodological Paper

An Update on Antioxidative Stress Therapy Research for Early Brain Injury After Subarachnoid Hemorrhage

Senescence in Primary Rat Astrocytes Induces Loss of the Mitochondrial Membrane Potential and Alters Mitochondrial Dynamics in Cortical Neurons

Severe Hypoglycemia Contributing to Cognitive Dysfunction in Diabetic Mice Is Associated With Pericyte and Blood–Brain Barrier Dysfunction