Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Brief Research Report

Published on 21 Feb 2022

Clinical Correlates Identify ProBDNF and Thrombo-Inflammatory Markers as Key Predictors of Circulating p75NTR Extracellular Domain Levels in Older Adults

in Cellular and Molecular Mechanisms of Brain-aging

Samuel Fleury
Mireille E. Schnitzer
Lawrence Ledoux-Hutchinson
Imane Boukhatem
Jean-Christophe Bélanger
Mélanie Welman
David Busseuil
Jean-Claude Tardif
Bianca D’Antono
Marie Lordkipanidzé

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.821865

6,322 views
1 citation

Original Research

Published on 21 Feb 2022

Mitoprotective Effects of a Synergistic Nutraceutical Combination: Basis for a Prevention Strategy Against Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Dona P. W. Jayatunga
Eugene Hone
W. M. A. D. Binosha Fernando
Manohar L. Garg
Giuseppe Verdile
Ralph N. Martins

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.781468

5,056 views
9 citations

Review

Published on 21 Feb 2022

Integrating Environment and Aging Research: Opportunities for Synergy and Acceleration

in Cellular and Molecular Mechanisms of Brain-aging

Kristen M. C. Malecki
Julie K. Andersen
Andrew M. Geller
G. Jean Harry
Chandra L. Jackson
Katherine A. James
Gary W. Miller
Mary Ann Ottinger

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.824921

7,754 views
24 citations

Review

Published on 17 Feb 2022

Age-Related Hearing Loss: Sensory and Neural Etiology and Their Interdependence

in Cellular and Molecular Mechanisms of Brain-aging

Karen L. Elliott
Bernd Fritzsch
Ebenezer N. Yamoah
Azel Zine

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.814528

7,452 views
35 citations

Original Research

Published on 16 Feb 2022

Extracellular Vesicles Derived From Plasma of Patients With Neurodegenerative Disease Have Common Transcriptomic Profiling

in Cellular and Molecular Mechanisms of Brain-aging

Daisy Sproviero
Stella Gagliardi
Susanna Zucca
Maddalena Arigoni
Marta Giannini
Maria Garofalo
Valentina Fantini
Orietta Pansarasa
Micol Avenali
Matteo Cotta Ramusino

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.785741

5,775 views
25 citations

Original Research

Published on 14 Feb 2022

Gradual Not Sudden Change: Multiple Sites of Functional Transition Across the Microvascular Bed

in Cellular and Molecular Mechanisms of Brain-aging

Kira Shaw
Katie Boyd
Silvia Anderle
Matthew Hammond-Haley
Davina Amin
Orla Bonnar
Catherine N. Hall

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.779823

5,304 views
13 citations

Editorial

Published on 09 Feb 2022

Editorial: Protein Misfolding and Proteostasis Impairment in Aging and Neurodegeneration: From Spreading Studies to Therapeutic Approaches

in Cellular and Molecular Mechanisms of Brain-aging

Claudia Duran-Aniotz
Ines Moreno-Gonzalez
Danilo B. Medinas
Rodrigo Morales

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.830779

4,038 views
5 citations

Original Research

Published on 08 Feb 2022

The Effect of Melatonin and Exercise on Social Isolation-Related Behavioral Changes in Aged Rats

in Cellular and Molecular Mechanisms of Brain-aging

Badrah Saeed Alghamdi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.828965

4,475 views
9 citations

Original Research

Published on 28 Jan 2022

The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons

in Cellular and Molecular Mechanisms of Brain-aging

Mingmei Ding
Xiaobing Qing
Guangyu Zhang
Carolin Baade-Büttner
Ralph Gruber
Haizhen Lu
David O. Ferguson
Christian Geis
Zhao-Qi Wang
Zhong-Wei Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.786199

4,401 views
5 citations

Original Research

Published on 14 Jan 2022

Dynamic Changes of Endogenic or Exogenic β-Carboline Alkaloid Harmine in Different Mammals and Human in vivo at Developmental and Physiological States

in Cellular and Molecular Mechanisms of Brain-aging

Ning Cao
Shuping Li
Aimin Xu
Manlin Li
Xiaoguang Zou
Zunji Ke
Gang Deng
Xuemei Cheng
Changhong Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.773638

5,813 views
6 citations

Original Research

Published on 11 Jan 2022

GABAA Receptors in Astrocytes Are Targets for Commonly Used Intravenous and Inhalational General Anesthetic Drugs

in Cellular and Molecular Mechanisms of Brain-aging

Woosuk Chung
Dian-Shi Wang
Shahin Khodaei
Arsene Pinguelo
Beverley A. Orser

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.802582

5,688 views
10 citations

Original Research

Published on 11 Jan 2022

Tau Knockout and α-Synuclein A53T Synergy Modulated Parvalbumin-Positive Neurons Degeneration Staging in Substantia Nigra Pars Reticulata of Parkinson’s Disease-Liked Model

in Cellular and Molecular Mechanisms of Brain-aging

Meige Zheng
Yanchang Liu
Zhaoming Xiao
Luyan Jiao
Xian Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.784665

3,605 views
4 citations

Original Research

Published on 06 Jan 2022

Selective and Inverse U-Shaped Curve Alteration of the Retinal Nerve in Amyotrophic Lateral Sclerosis: A Potential Mirror of the Disease

in Cellular and Molecular Mechanisms of Brain-aging

Yixuan Zhang
Xiangyi Liu
Jiayu Fu
Yuanjin Zhang
Xue Yang
Shuo Zhang
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.783431

2,548 views
7 citations

Review

Published on 05 Jan 2022

Aged Microglia in Neurodegenerative Diseases: Microglia Lifespan and Culture Methods

in Cellular and Molecular Mechanisms of Brain-aging

Hyun-Jung Yoo
Min-Soo Kwon

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.766267

16,917 views
45 citations

Review

Published on 04 Jan 2022

Retrotransposons as a Source of DNA Damage in Neurodegeneration

in Cellular and Molecular Mechanisms of Brain-aging

Eugenie Peze-Heidsieck
Tom Bonnifet
Rania Znaidi
Camille Ravel-Godreuil
Olivia Massiani-Beaudoin
Rajiv L. Joshi
Julia Fuchs

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.786897

10,635 views
26 citations

Original Research

Published on 03 Jan 2022

MRI Volumetric Analysis of the Thalamus and Hypothalamus in Amyotrophic Lateral Sclerosis

in Cellular and Molecular Mechanisms of Brain-aging

Shan Ye
Yishan Luo
Pingping Jin
Yajun Wang
Nan Zhang
Gan Zhang
Lu Chen
Lin Shi
Dongsheng Fan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.610332

4,628 views
8 citations