Frontiers in Aging Neuroscience | Cellular and Molecular Mechanisms of Brain-aging

Original Research

Published on 04 Mar 2022

Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways

in Cellular and Molecular Mechanisms of Brain-aging

Lichi Xu
Yanjing Guo
Gongming Wang
Guoqing Sun
Wei Sun
Jingjing Li
Xinlei Li
Jiangnan Wu
Mengyuan Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.782932

3,712 views
15 citations

Original Research

Published on 03 Mar 2022

Neurons Release Injured Mitochondria as “Help-Me” Signaling After Ischemic Stroke

in Cellular and Molecular Mechanisms of Brain-aging

Li Gao
Fan Liu
Pin-Pin Hou
Anatol Manaenko
Zhi-Peng Xiao
Fei Wang
Tian-Le Xu
Qin Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.785761

9,147 views
21 citations

Review

Published on 02 Mar 2022

The Interplay Between Brain Vascular Calcification and Microglia

in Cellular and Molecular Mechanisms of Brain-aging

Upasana Maheshwari
Sheng-Fu Huang
Sucheta Sridhar
Annika Keller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.848495

13,618 views
18 citations

Original Research

Published on 28 Feb 2022

Genetic and Molecular Evaluation of SQSTM1/p62 on the Neuropathologies of Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Wei Dong
Meng-Chao Cui
Wen-Zheng Hu
Qi Zeng
Yi-Long Wang
Wei Zhang
Yue Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.829232

4,548 views
12 citations

Review

Published on 25 Feb 2022

Variability in Retinal Neuron Populations and Associated Variations in Mass Transport Systems of the Retina in Health and Aging

in Cellular and Molecular Mechanisms of Brain-aging

Moussa A. Zouache

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.778404

5,535 views
14 citations

Original Research

Published on 24 Feb 2022

Behavioral and Cellular Tagging in Young and in Early Cognitive Aging

in Cellular and Molecular Mechanisms of Brain-aging

Alexandra Gros
Amos W. H. Lim
Victoria Hohendorf
Nicole White
Michael Eckert
Thomas John McHugh
Szu-Han Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.809879

3,655 views
7 citations

Brief Research Report

Published on 21 Feb 2022

Clinical Correlates Identify ProBDNF and Thrombo-Inflammatory Markers as Key Predictors of Circulating p75NTR Extracellular Domain Levels in Older Adults

in Cellular and Molecular Mechanisms of Brain-aging

Samuel Fleury
Mireille E. Schnitzer
Lawrence Ledoux-Hutchinson
Imane Boukhatem
Jean-Christophe Bélanger
Mélanie Welman
David Busseuil
Jean-Claude Tardif
Bianca D’Antono
Marie Lordkipanidzé

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.821865

6,230 views
1 citation

Original Research

Published on 21 Feb 2022

Mitoprotective Effects of a Synergistic Nutraceutical Combination: Basis for a Prevention Strategy Against Alzheimer’s Disease

in Cellular and Molecular Mechanisms of Brain-aging

Dona P. W. Jayatunga
Eugene Hone
W. M. A. D. Binosha Fernando
Manohar L. Garg
Giuseppe Verdile
Ralph N. Martins

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.781468

4,881 views
6 citations

Review

Published on 21 Feb 2022

Integrating Environment and Aging Research: Opportunities for Synergy and Acceleration

in Cellular and Molecular Mechanisms of Brain-aging

Kristen M. C. Malecki
Julie K. Andersen
Andrew M. Geller
G. Jean Harry
Chandra L. Jackson
Katherine A. James
Gary W. Miller
Mary Ann Ottinger

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.824921

7,260 views
22 citations

Review

Published on 17 Feb 2022

Age-Related Hearing Loss: Sensory and Neural Etiology and Their Interdependence

in Cellular and Molecular Mechanisms of Brain-aging

Karen L. Elliott
Bernd Fritzsch
Ebenezer N. Yamoah
Azel Zine

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.814528

7,074 views
33 citations

Original Research

Published on 16 Feb 2022

Extracellular Vesicles Derived From Plasma of Patients With Neurodegenerative Disease Have Common Transcriptomic Profiling

in Cellular and Molecular Mechanisms of Brain-aging

Daisy Sproviero
Stella Gagliardi
Susanna Zucca
Maddalena Arigoni
Marta Giannini
Maria Garofalo
Valentina Fantini
Orietta Pansarasa
Micol Avenali
Matteo Cotta Ramusino

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.785741

5,575 views
23 citations

Original Research

Published on 14 Feb 2022

Gradual Not Sudden Change: Multiple Sites of Functional Transition Across the Microvascular Bed

in Cellular and Molecular Mechanisms of Brain-aging

Kira Shaw
Katie Boyd
Silvia Anderle
Matthew Hammond-Haley
Davina Amin
Orla Bonnar
Catherine N. Hall

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.779823

5,086 views
11 citations

Editorial

Published on 09 Feb 2022

Editorial: Protein Misfolding and Proteostasis Impairment in Aging and Neurodegeneration: From Spreading Studies to Therapeutic Approaches

in Cellular and Molecular Mechanisms of Brain-aging

Claudia Duran-Aniotz
Ines Moreno-Gonzalez
Danilo B. Medinas
Rodrigo Morales

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.830779

3,874 views
4 citations

Original Research

Published on 08 Feb 2022

The Effect of Melatonin and Exercise on Social Isolation-Related Behavioral Changes in Aged Rats

in Cellular and Molecular Mechanisms of Brain-aging

Badrah Saeed Alghamdi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2022.828965

4,384 views
8 citations

Original Research

Published on 28 Jan 2022

The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons

in Cellular and Molecular Mechanisms of Brain-aging

Mingmei Ding
Xiaobing Qing
Guangyu Zhang
Carolin Baade-Büttner
Ralph Gruber
Haizhen Lu
David O. Ferguson
Christian Geis
Zhao-Qi Wang
Zhong-Wei Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.786199

4,174 views
5 citations

Original Research

Published on 14 Jan 2022

Dynamic Changes of Endogenic or Exogenic β-Carboline Alkaloid Harmine in Different Mammals and Human in vivo at Developmental and Physiological States

in Cellular and Molecular Mechanisms of Brain-aging

Ning Cao
Shuping Li
Aimin Xu
Manlin Li
Xiaoguang Zou
Zunji Ke
Gang Deng
Xuemei Cheng
Changhong Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2021.773638

5,669 views
6 citations

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Articles

Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways

Neurons Release Injured Mitochondria as “Help-Me” Signaling After Ischemic Stroke

The Interplay Between Brain Vascular Calcification and Microglia

Genetic and Molecular Evaluation of SQSTM1/p62 on the Neuropathologies of Alzheimer’s Disease

Variability in Retinal Neuron Populations and Associated Variations in Mass Transport Systems of the Retina in Health and Aging

Behavioral and Cellular Tagging in Young and in Early Cognitive Aging

Clinical Correlates Identify ProBDNF and Thrombo-Inflammatory Markers as Key Predictors of Circulating p75NTR Extracellular Domain Levels in Older Adults

Mitoprotective Effects of a Synergistic Nutraceutical Combination: Basis for a Prevention Strategy Against Alzheimer’s Disease

Integrating Environment and Aging Research: Opportunities for Synergy and Acceleration

Age-Related Hearing Loss: Sensory and Neural Etiology and Their Interdependence

Extracellular Vesicles Derived From Plasma of Patients With Neurodegenerative Disease Have Common Transcriptomic Profiling

Gradual Not Sudden Change: Multiple Sites of Functional Transition Across the Microvascular Bed

Editorial: Protein Misfolding and Proteostasis Impairment in Aging and Neurodegeneration: From Spreading Studies to Therapeutic Approaches

The Effect of Melatonin and Exercise on Social Isolation-Related Behavioral Changes in Aged Rats

The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons

Dynamic Changes of Endogenic or Exogenic β-Carboline Alkaloid Harmine in Different Mammals and Human in vivo at Developmental and Physiological States