Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Published on 08 Aug 2019

The Influence of Cerebrospinal Fluid Abnormalities and APOE 4 on PHF-Tau Protein: Evidence From Voxel Analysis and Graph Theory

in Alzheimer's Disease and Related Dementias

Yuan Li
Zhijun Yao
Yue Yu
Yu Fu
Ying Zou
Bin Hu
for the Alzheimer’s Disease Neuroimaging Initiative
Michael W. Weiner
Paul Aisen
Michael Weiner

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00208

6,415 views
3 citations

Review

Published on 07 Aug 2019

Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects

in Alzheimer's Disease and Related Dementias

Pascale Barbier
Orgeta Zejneli
Marlène Martinho
Alessia Lasorsa
Valérie Belle
Caroline Smet-Nocca
Philipp O. Tsvetkov
François Devred
Isabelle Landrieu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00204

87,354 views
511 citations

Review

Published on 07 Aug 2019

Entanglement of CCR5 and Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Tianwen Li
Jianhong Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00209

16,777 views
33 citations

Original Research

Published on 02 Aug 2019

Predicting MCI Status From Multimodal Language Data Using Cascaded Classifiers

in Alzheimer's Disease and Related Dementias

Kathleen C. Fraser
Kristina Lundholm Fors
Marie Eckerström
Fredrik Öhman
Dimitrios Kokkinakis

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00205

11,301 views
90 citations

Original Research

Published on 31 Jul 2019

Layer-Wise Relevance Propagation for Explaining Deep Neural Network Decisions in MRI-Based Alzheimer's Disease Classification

in Alzheimer's Disease and Related Dementias

Moritz Böhle
Fabian Eitel
Martin Weygandt
Kerstin Ritter

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00194

43,306 views
263 citations

Opinion

Published on 24 Jul 2019

Ketamine: A Neglected Therapy for Alzheimer Disease

in Alzheimer's Disease and Related Dementias

Neil R. Smalheiser

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00186

45,557 views
29 citations

Brief Research Report

Published on 23 Jul 2019

The Synthetic Retinoid Acitretin Increases IL-6 in the Central Nervous System of Alzheimer Disease Model Mice and Human Patients

in Alzheimer's Disease and Related Dementias

Malena dos Santos Guilherme
Nicolai M. Stoye
Stefan Rose-John
Christoph Garbers
Andreas Fellgiebel
Kristina Endres

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00182

6,865 views
24 citations

Opinion

Published on 23 Jul 2019

Aging, Metabolism, Synaptic Activity, and Aβ in Alzheimer's Disease

in Alzheimer's Disease and Related Dementias

Gunnar K. Gouras

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00185

4,902 views
11 citations

Mini Review

Published on 17 Jul 2019

Liver Dysfunction as a Novel Player in Alzheimer’s Progression: Looking Outside the Brain

in Alzheimer's Disease and Related Dementias

Lisbell D. Estrada
Pablo Ahumada
Daniel Cabrera
Juan P. Arab

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00174

24,950 views
136 citations

Original Research

Published on 17 Jul 2019

Pioglitazone Reduces β Amyloid Levels via Inhibition of PPARγ Phosphorylation in a Neuronal Model of Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Qiankun Quan
Yihua Qian
Xi Li
Ming Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00178

5,801 views
53 citations

Original Research

Published on 16 Jul 2019

Radiomic Features of the Nigrosome-1 Region of the Substantia Nigra: Using Quantitative Susceptibility Mapping to Assist the Diagnosis of Idiopathic Parkinson's Disease

in Alzheimer's Disease and Related Dementias

Zenghui Cheng
Jiping Zhang
Naying He
Yan Li
Yaofeng Wen
Hongmin Xu
Rongbiao Tang
Zhijia Jin
E. Mark Haacke
Fuhua Yan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00167

12,100 views
63 citations

Systematic Review

Published on 11 Jul 2019

Dopamine and Dopamine Receptors in Alzheimer's Disease: A Systematic Review and Network Meta-Analysis

in Alzheimer's Disease and Related Dementias

Xiongfeng Pan
Atipatsa C. Kaminga
Shi Wu Wen
Xinyin Wu
Kwabena Acheampong
Aizhong Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00175

42,720 views
236 citations

Review

Published on 04 Jul 2019

Early Secure Attachment as a Protective Factor Against Later Cognitive Decline and Dementia

in Alzheimer's Disease and Related Dementias

Emilie Walsh
Yvonne Blake
Alessia Donati
Ron Stoop
Armin von Gunten

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00161

43,290 views
72 citations

Review

Published on 26 Jun 2019

The Post-amyloid Era in Alzheimer's Disease: Trust Your Gut Feeling

in Alzheimer's Disease and Related Dementias

Carolina Osorio
Tulasi Kanukuntla
Eddie Diaz
Nyla Jafri
Michael Cummings
Adonis Sfera

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00143

23,106 views
47 citations

Review

Published on 24 Jun 2019

Modifiable Risk Factors for Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

George A. Edwards III
Nazaret Gamez
Gabriel Escobedo Jr.
Olivia Calderon
Ines Moreno-Gonzalez

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00146

66,244 views
214 citations

Brief Research Report

Published on 21 Jun 2019

Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Mar Cuadrado-Tejedor
Marta Pérez-González
Cristina García-Muñoz
Damián Muruzabal
Carolina García-Barroso
Obdulia Rabal
Víctor Segura
Juan A. Sánchez-Arias
Julen Oyarzabal
Ana Garcia-Osta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00149

7,524 views
42 citations

Original Research

Published on 12 Jun 2019

Insulin Resistance Is a Risk Factor for Overall Cerebral Small Vessel Disease Burden in Old Nondiabetic Healthy Adult Population

in Alzheimer's Disease and Related Dementias

Xiaoli Yang
Shufan Zhang
Zhiyuan Dong
Yincui Zi
Yufan Luo
Zhi Jin
Lei Shi
Chen Li
Chuanchen Ren
Danhong Wu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00127

5,431 views
30 citations

Original Research

Published on 11 Jun 2019

Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer’s Disease

in Alzheimer's Disease and Related Dementias

Mercedes Lachen-Montes
Andrea González-Morales
Maialen Palomino
Karina Ausin
Marta Gómez-Ochoa
María Victoria Zelaya
Isidro Ferrer
Alberto Pérez-Mediavilla
Joaquín Fernández-Irigoyen
Enrique Santamaría

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00141

5,107 views
15 citations

Original Research

Published on 05 Jun 2019

Alcohol Dehydrogenase 1B Suppresses β-Amyloid-Induced Neuron Apoptosis

in Alzheimer's Disease and Related Dementias

Yaqi Wang
Yi Zhang
Xiaomin Zhang
Tingting Yang
Chengeng Liu
Peichang Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00135

6,360 views
12 citations

Review

Published on 31 May 2019

Lifespan Intellectual Factors, Genetic Susceptibility, and Cognitive Phenotypes in Aging: Implications for Interventions

in Alzheimer's Disease and Related Dementias

Yongxiang Wang
Yifeng Du
Juan Li
Chengxuan Qiu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00129

11,885 views
48 citations

Opinion

Published on 31 May 2019

Addressing Disparities in Alzheimer's Disease and African-American Participation in Research: An Asset-Based Community Development Approach

in Alzheimer's Disease and Related Dementias

Gina Green-Harris
Sheryl L. Coley
Rebecca L. Koscik
Nia C. Norris
Stephanie L. Houston
Mark A. Sager
Sterling C. Johnson
Dorothy Farrar Edwards

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00125

13,552 views
42 citations

Original Research

Published on 28 May 2019

Involvement of Oligodendrocytes in Tau Seeding and Spreading in Tauopathies

in Alzheimer's Disease and Related Dementias

Isidro Ferrer
Meritxell Aguiló García
Margarita Carmona
Pol Andrés-Benito
Benjamin Torrejón-Escribano
Paula Garcia-Esparcia
José Antonio del Rio

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00112

10,608 views
66 citations

Original Research

Published on 28 May 2019

Decreased Netrin-1 and Correlated Th17/Tregs Balance Disorder in Aβ1–42 Induced Alzheimer’s Disease Model Rats

in Alzheimer's Disease and Related Dementias

Lina Sun
Ting Ju
Tianhang Wang
Liang Zhang
Feifan Ding
Yan Zhang
Ran An
Yilei Sun
You Li
Yidan Lu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00124

5,971 views
41 citations

Opinion

Published on 28 May 2019

Infection-Induced Systemic Inflammation Is a Potential Driver of Alzheimer's Disease Progression

in Alzheimer's Disease and Related Dementias

Vijayasree V. Giridharan
Faisal Masud
Fabricia Petronilho
Felipe Dal-Pizzol
Tatiana Barichello

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2019.00122

10,237 views
57 citations

2,200 articles

articles

The Influence of Cerebrospinal Fluid Abnormalities and APOE 4 on PHF-Tau Protein: Evidence From Voxel Analysis and Graph Theory

Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects

Entanglement of CCR5 and Alzheimer’s Disease

Predicting MCI Status From Multimodal Language Data Using Cascaded Classifiers

Layer-Wise Relevance Propagation for Explaining Deep Neural Network Decisions in MRI-Based Alzheimer's Disease Classification

Ketamine: A Neglected Therapy for Alzheimer Disease

The Synthetic Retinoid Acitretin Increases IL-6 in the Central Nervous System of Alzheimer Disease Model Mice and Human Patients

Aging, Metabolism, Synaptic Activity, and Aβ in Alzheimer's Disease

Liver Dysfunction as a Novel Player in Alzheimer’s Progression: Looking Outside the Brain

Pioglitazone Reduces β Amyloid Levels via Inhibition of PPARγ Phosphorylation in a Neuronal Model of Alzheimer’s Disease

Radiomic Features of the Nigrosome-1 Region of the Substantia Nigra: Using Quantitative Susceptibility Mapping to Assist the Diagnosis of Idiopathic Parkinson's Disease

Dopamine and Dopamine Receptors in Alzheimer's Disease: A Systematic Review and Network Meta-Analysis

Early Secure Attachment as a Protective Factor Against Later Cognitive Decline and Dementia

The Post-amyloid Era in Alzheimer's Disease: Trust Your Gut Feeling

Modifiable Risk Factors for Alzheimer’s Disease

Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer’s Disease

Insulin Resistance Is a Risk Factor for Overall Cerebral Small Vessel Disease Burden in Old Nondiabetic Healthy Adult Population

Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer’s Disease

Alcohol Dehydrogenase 1B Suppresses β-Amyloid-Induced Neuron Apoptosis

Lifespan Intellectual Factors, Genetic Susceptibility, and Cognitive Phenotypes in Aging: Implications for Interventions

Addressing Disparities in Alzheimer's Disease and African-American Participation in Research: An Asset-Based Community Development Approach

Involvement of Oligodendrocytes in Tau Seeding and Spreading in Tauopathies

Decreased Netrin-1 and Correlated Th17/Tregs Balance Disorder in Aβ1–42 Induced Alzheimer’s Disease Model Rats

Infection-Induced Systemic Inflammation Is a Potential Driver of Alzheimer's Disease Progression