Frontiers in Aging Neuroscience | Alzheimer's Disease and Related Dementias

Original Research

Accepted on 08 Jul 2025

miR-423-5p and miR-92a-3p in Alzheimer's disease: relationship with pathology and cognition

in Alzheimer's Disease and Related Dementias

Sang-Won Han
Young Ho Park
Jung-Min Pyun
Paula J. Bice
SangYun Kim
Andrew J. Saykin
Kwangsik Nho

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637368

Original Research

Published on 07 Jul 2025

Quantitative analysis of targeted lipidomics in the hippocampus of APP/PS1 mice employing the UHPLC-MS/MS method

in Alzheimer's Disease and Related Dementias

Shiyu Xiao
Xuemeng Wei
Bing Han
Xiaoqian Shi
Congzhen Wei
Rumeng Liang
Jingna Sun
Zheng Zhang
Zhengang Han
Li Shen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1561831

427 views

Mini Review

Published on 04 Jul 2025

Perspectives on resting-state functional magnetic resonance imaging research in vascular dementia

in Alzheimer's Disease and Related Dementias

Jinhuan Yue
Peng Wang
Xiang-fa Guo
Zeyi Wei
Kaiting He
Nuo Li
Xiaoling Li
Qinhong Zhang
Xiaoqing Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547965

692 views

Mini Review

Accepted on 03 Jul 2025

GLP-1R as a potential link between diabetes and Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Shujun Li
Nanqu Huang
Mei Wang
Wendi Huang
Jing-Shan Shi
Yong Luo
Juan Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1601602

288 views

Brief Research Report

Published on 03 Jul 2025

Relationship between tau-PET and quantitative susceptibility mapping in atypical Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Neha Singh-Reilly
Ryota Satoh
Jonathan Graff-Radford
Mary M. Machulda
Val J. Lowe
Keith A. Josephs
Jennifer L. Whitwell

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1615718

493 views

Review

Accepted on 02 Jul 2025

Elucidating Molecular Pathogenesis and Developing Targeted Therapeutic Interventions for Cerebrovascular Endothelial Cell-Mediated Vascular Dementia

in Alzheimer's Disease and Related Dementias

Yanrong Yang
Hua Chen
Qibing Liu
Yang Niu
Rui WANG

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1623050

173 views

Original Research

Accepted on 02 Jul 2025

Region-Informed Machine Learning Model for Choroid Plexus Segmentation in Alzheimer's Disease

in Alzheimer's Disease and Related Dementias

Liangdong Zhou
Tracy Butler
Xiuyuan Wang
Samantha A Keil
Seyed Hani Hojjati
Tsung-Wei Hu
Mélissa Savard
Firoza Z Lussier
Pedro Rosa-Neto MD PhD
Lidia Glodzik

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1613320

203 views

Original Research

Published on 02 Jul 2025

Hippocampal iron patterns in aging and mild cognitive impairment

in Alzheimer's Disease and Related Dementias

Sonja M. Kagerer
Laetitia Vionnet
Jiri M. G. van Bergen
Rafael Meyer
Anton F. Gietl
Klaas P. Pruessmann
Christoph Hock
Paul G. Unschuld

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1598859

331 views

Original Research

Published on 02 Jul 2025

Research hotspots and frontiers of glymphatic system and Alzheimer’s disease: a bibliometrics analysis

in Alzheimer's Disease and Related Dementias

Shichao Liu
Lvping Zhuang
Xiaochun Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579373

538 views

Original Research

Published on 02 Jul 2025

Serum uric acid to creatinine ratio in patients with early-onset post-stroke cognitive impairment: a retrospective cohort study

in Alzheimer's Disease and Related Dementias

Libin Liao
Weiquan Huang
Rongchao Ma
Wentong Hu
Hui Wu
Moxi Su
Dujuan Sha

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1580722

384 views

Original Research

Accepted on 30 Jun 2025

Estimating Progression of Alzheimer's Disease with Extracellular Vesicle-Related Multi-Omics Risk Models

in Alzheimer's Disease and Related Dementias

Xiao Zhang
Sanoji Wijenayake
Shakhawat Hossain
Qian Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617611

181 views

Review

Accepted on 27 Jun 2025

Insights into targeted ferroptosis in mechanisms, biology, and role of Alzheimer's disease：An Update

in Alzheimer's Disease and Related Dementias

Zhou Bingyuan
Jing Li
Anqi Wu
Xuewei Wang
Cheng Le
Gaoshang Yang
Dahong Gao
Caifeng Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587986

152 views

Original Research

Published on 27 Jun 2025

Age-sex differences in Alzheimer’s and related dementias burden and risk factors in east and Southeast Asia: results from the 2021 GBD study

in Alzheimer's Disease and Related Dementias

Tengyu Zhao
Pengyu Pan
Yuhan Zhou
Xinyue Zhang
Quan Li
Yanyan Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562148

536 views

Original Research

Accepted on 26 Jun 2025

Quantitative Assessment of Brain glymphatic Imaging Features Using Deep Learning-Based EPVS Segmentation and DTI-ALPS Analysis in Alzheimer's Disease

in Alzheimer's Disease and Related Dementias

Chen Fen Yang
Tiantian Heng
Qi Feng
Rui Hua
Feng Shi
Zhengluan Liao
Keyin Qiao
Zhiliang Zhang
Jianliang Miao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1621106

250 views

Original Research

Published on 25 Jun 2025

Voxel- and surface-based morphometry in the cortical thickness and cortical and subcortical gray matter volume in patients with mild-to-moderate Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Kaidi Li
Dingling Xie
Zhengyong Zhang
Chunyu Fu
Chunyang Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1546977

647 views

Original Research

Published on 24 Jun 2025

A new pathway for neuroprotection against tau hyperphosphorylation via δ-opioid receptor initiated inhibition of CDK5 and AMPK signaling

in Alzheimer's Disease and Related Dementias

Jiahui Li
Yuan Xu
Gianfranco Balboni
Ying Xia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587219

713 views