Skip to main content

REVIEW article

Front. Psychiatry, 10 November 2022
Sec. Aging Psychiatry
This article is part of the Research Topic Use of technology in Dementia Care View all 5 articles

Real-time location systems technology in the care of older adults with cognitive impairment living in residential care: A scoping review

  • 1KITE Research Institute, Toronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada
  • 2Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, ON, Canada
  • 3School of Physiotherapy, Dalhousie University, Halifax, NS, Canada
  • 4Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada
  • 5Centre for Mental Health, University Health Network, Toronto, ON, Canada

Introduction: There has been growing interest in using real-time location systems (RTLS) in residential care settings. This technology has clinical applications for locating residents within a care unit and as a nurse call system, and can also be used to gather information about movement, location, and activity over time. RTLS thus provides health data to track markers of health and wellbeing and augment healthcare decisions. To date, no reviews have examined the potential use of RTLS data in caring for older adults with cognitive impairment living in a residential care setting.

Objective: This scoping review aims to explore the use of data from real-time locating systems (RTLS) technology to inform clinical measures and augment healthcare decision-making in the care of older adults with cognitive impairment who live in residential care settings.

Methods: Embase (Ovid), CINAHL (EBSCO), APA PsycINFO (Ovid) and IEEE Xplore databases were searched for published English-language articles that reported the results of studies that investigated RTLS technologies in persons aged 50 years or older with cognitive impairment who were living in a residential care setting. Included studies were summarized, compared and synthesized according to the study outcomes.

Results: A total of 27 studies were included. RTLS data were used to assess activity levels, characterization of wandering, cognition, social interaction, and to monitor a resident’s health and wellbeing. These RTLS-based measures were not consistently validated against clinical measurements or clinically important outcomes, and no studies have examined their effectiveness or impact on decision-making.

Conclusion: This scoping review describes how data from RTLS technology has been used to support clinical care of older adults with dementia. Research efforts have progressed from using the data to track activity levels to, most recently, using the data to inform clinical decision-making and as a predictor of delirium. Future studies are needed to validate RTLS-based health indices and examine how these indices can be used to inform decision-making.

Introduction

As those with dementia require increasing support for daily functioning, many relocate to assisted living environments. The umbrella term “residential care” is often used to reflect the continuum of assisted living environments designed to facilitate and support an older adult’s functional independence. The majority of those living within a residential care setting in industrialized countries have dementia or cognitive impairment (13). As most of these residential care settings have a limited staff-to-resident ratio, technology utilization may potentially help to alleviate resource gaps and augment care delivery.

There have been several reviews on the use of technologies in older adults with dementia to measure clinical variables, such as detection of behavioral symptoms (4), monitoring of treatment response (5), prediction of falls risk (6), gait analysis (7), and physical activity levels (8). These reviews were not exclusive to the uses of technology in residential care settings, and they examined various wearable and non-wearable and environmental sensors. A systematic review by Lynn et al. (9) identified technologies used in residential care settings. The technology categories included were largely resident-facing technologies, such as telecare, light therapy, robotics (e.g., robotic companion), wellbeing and leisure (e.g., touch screen devices, watches to measure sleep cycles), simulated presence and orientation (e.g., audio/video recordings), and activities of daily living (e.g., handwashing, taking medication memory aids). We are unaware of any reviews examining provider-facing technologies designed to support clinical decision-making in residential care.

One particular provider-facing technology in residential care are real-time locating systems (RTLS). RTLS, also known as indoor positioning or location systems, are primarily used for tracking individuals and equipment in indoor environments in real or near-real time or incorporated into nurse call or safety systems (10, 11). A RTLS typically consists of a wearable device that contains a sensor (e.g., a tag or bracelet) that is worn by an individual, a number of environmentally embedded receiver devices (e.g., beacons on the ceiling), and software in order to visualize location data on a facility map, connected on a wireless network to continuously track people or items in real time. Non-wearable sensor technologies can be deployed as RTLS in clinical settings, such as near-field radio-frequency ID (RFID) tags or passive infra-red (IR) sensors, which detect movements of individuals passing through doors or at a room-level scale. Higher accuracy, wearable systems such as Bluetooth or Ultra-wide band (UWB) are used when the intention is to collect within-room movement patterns at a regular sampling rate over time. RTLS provides a vast amount of data on an individual’s location over time and can characterize movement through a well-defined target environment. RTLS installations have been studied in a wide variety of health care settings to monitor individuals’ movements (e.g., residents/patients, staff) and assets (e.g., surgical equipment) (1215).

In a previous technical review, the authors identified the ways in which meaning can be extracted from RTLS data to describe human behaviors in a variety of different settings (healthcare, education, workplaces, shopping malls, art galleries) (11). We have also completed a previous systematic review to identify factors that affect the implementation of RTLS for use with persons living with dementia in long-term care homes (16). However, neither of these reviews addressed the ways in which RTLS data was being used as a clinical outcome or how the data was used to inform clinical decision-making processes. As this type of technology becomes more common within residential care settings, there is a need to understand the potential uses of the collected RTLS data to provide clinical insights and augment healthcare decisions.

Thus, this scoping review aims to describe the available evidence on the use of data from RTLS technology to inform clinical measures, demonstrate validation of clinical measurements, or augment healthcare decision-making in persons with cognitive impairment living in residential care. A preliminary search of MEDLINE, the Cochrane Database of Systematic Reviews, and JBI Evidence Synthesis did not identify any current or in-progress scoping reviews or systematic reviews on this topic. Understanding this literature is important, as synthesizing this information can shape future studies to identify the optimal use of RTLS technology in this population of older adults.

Review questions

1. How are data from RTLS technologies used to support the clinical care of older adults with cognitive impairment residing in a residential care setting?

2. How have RTLS data been used to inform or validate clinical measures for the clinical care of people with cognitive impairment in residential care settings?

Inclusion criteria

Participants

This scoping review considered studies of persons 50 years of age or older who lived in a residential care setting. We opted to use an age criterion to exclude residential care settings for people with cognitive impairments that do not primarily care for older adults, such as group homes. A cut-off of 50 years old was selected to avoid excluding individuals with early onset dementia. Studies were included if the majority of study participants had cognitive impairment or dementia.

Concept

This review considered studies that examined the use of RTLS. RTLS consists of a software application and reference points that detect and synthesize positioning data from wireless transmitters worn by people or attached to objects, enabling the collection of several indices (e.g., tracking movement and activity levels) that locate a person in space over time. The technology may include RFID, UWB, GPS, or other sensor-based systems. Outcomes of interest for this review included identifying how clinicians use this RTLS data to augment clinical assessment and clinical decision-making processes.

Context

This review considered studies in which study participants resided within an assisted living environment, a residential environment that supports or enables older adults with or without cognitive impairment. For this review, a residential care environment includes assisted living facilities (e.g., retirement homes or group homes), long-term care facilities (e.g., nursing homes), or special dementia care units within the community or hospital settings.

Types of sources

For this scoping review, we included published original research exploring the use of RTLS technology in older adults with dementia living in a residential care setting. We considered quantitative, qualitative, case studies, case reports, and mixed methods study designs for inclusion. Commentaries and publications with hypothetical uses of the technology were excluded (Table 1). Conference papers and abstracts were included, but if they did not contain clinical data, or were duplicated in a peer-reviewed publication, they were excluded. We did not include books, study protocols, or previous reviews.

TABLE 1
www.frontiersin.org

Table 1. Inclusion and exclusion criteria.

The review was limited to studies published in English. A systematic review has demonstrated that restricting the search strategy to English-language publications has little impact on the conclusions for most medical topics (17).

Materials and methods

This scoping review was conducted in accordance with the JBI methodology for scoping reviews (18) and the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Statement (19) (Supplementary Appendix 3). The PRISMA-ScR framework provides guidance on the reporting of items required within a scoping review. The protocol for this scoping review was published a priori via the Open Science Framework.1 The protocol was amended to modify the exclusion criteria after our initial search: for example, we omitted papers that “mapped” clinical environments, but patient data was not collected.

Search strategy

The search strategy aimed to locate peer-reviewed published studies. This scoping review follows the work of two previous reviews (11, 16) that focused on implementation/ethics of RTLS technologies and data analytic approaches for RTLS data. We worked with an information specialist who is trained in comprehensive searching methods for knowledge synthesis and has experience in conducting scoping reviews to plan and execute the search strategy. The text words contained in the titles and abstracts of relevant articles, and the index terms used to describe the articles were used to develop a full search strategy. The search strategy, including all identified keywords and index terms, was adapted for each included information source (Table 2). The search encompassed literature from the inception of each database to September 2021. Reference lists of the included literature were hand searched for additional relevant studies. A sample of the search strategy is provided in Supplementary Appendix 1.

TABLE 2
www.frontiersin.org

Table 2. Search strategy terms.

The databases searched include: Embase Classic + Embase (Ovid) Medline (including Epub Ahead of Print, In-Process and Other Non-Indexed Citations, Ovid MEDLINE® Daily and Ovid MEDLINE®, in Ovid), CINAHL (EBSCO), APA PsycINFO (Ovid) and IEEE Xplore. Unpublished studies, conference abstracts, and gray literature were not included.

Source of evidence selection

Following the search, all citations were uploaded to Covidence systemic review software (Veritas Health Innovation, Melbourne, Australia) and duplicates were removed. After a pilot test of screening criteria, titles and abstracts were screened by two independent reviewers (LH-L, LS) for assessment against the inclusion criteria for the review. Potentially relevant papers were retrieved in full and uploaded into Covidence. Two reviewers assessed these studies independently to determine if they met the study criteria (LH-L, LS). Any disagreements between the reviewers at each stage were resolved by consensus or with a third reviewer (AI). For each study a quality appraisal was conducted using the appropriate JBI Quality Appraisal tool (Supplementary Appendix 2).

Data extraction

Data were extracted from papers included in the scoping review by two independent reviewers (LH-L, LS) using a data extraction tool within Covidence and developed by the reviewers. The data extracted included specific details about the aim of the study, study design, participant characteristics, years data was collected (if available), associations/relationships to other studies, residential home characteristics, the type of tracking technology, how the technology was used, measurements used, comparisons between measurements, and key findings relevant to the review question. Any disagreements that arose between the reviewers were resolved through discussion or with a third reviewer. Authors of papers were contacted to request missing or additional data, where required. Upon review of the final data extraction sheet, we used a content analysis approach to identify common themes amongst the literature. We were then able to compare and contrast findings in relationship to these themes.

Data analysis and presentation

Results are reported graphically with tables when possible. The narrative that accompanies the tables further describes the body of literature. The review findings are reported in five broad themes: levels of activity, wandering or risk of wandering, cognitive status, proximity to others/social interaction, and other measures of health status. These themes were identified as potential areas of clinical care supported by RTLS technology through the process of the review.

Results

Study inclusion

A total of 982 articles were identified and uploaded to Covidence for screening. Of these, 492 were duplicates. At the title and abstract phase, 488 studies were screened, with 388 studies found ineligible. There were 100 full-text studies assessed for eligibility through full-text screening, and 73 were excluded (see Figure 1). Examining the included papers’ reference lists resulted in nine additional studies for inclusion.

FIGURE 1
www.frontiersin.org

Figure 1. Search results and study selection and inclusion process (19).

Reasons for exclusion were as follows: no clinical application of technology (20), not RTLS technology (18), not a primary research study (17), the population did not meet inclusion criteria (10), article not in English (2), and no full text available (2). The resulting 27 studies were included in the review.

Characteristics of included studies

The majority of the papers were from the United States (n = 12) (12, 13, 2029), and Japan (n = 9) (3038), and one each from Italy (39), Germany (14), France (40), Austria (41), Netherlands (42), and Hong Kong (43). No studies were excluded based on age criteria. The youngest participant across all studies was 54.

Studies were published across the date range of 2002 to 2021. Only one study was published in 2002 (40) with remaining studies published after 2007. The included research studies used various research designs, including cross-sectional (n = 16) (14, 20, 2325, 28, 3034, 3638, 41, 43), longitudinal (n = 5) (12, 13, 22, 27, 42), case reports (n = 4) (26, 35, 39, 40), and one of a case series (21).

Ten studies used UWB technology (12, 13, 20, 2225, 27, 28, 41). Other technologies used included RFID (IC tag) (n = 8) (30, 31, 3338), radio waves (Emerald ®) (n = 3) (21, 26, 29), Bluetooth (n = 3) (32, 39, 43), and one each of GPS technology (42) passive IR (40) and an unspecified wireless mesh network (Wi-Fi) (14).

The quality of the evidence is reported in Supplementary Appendix 2. Study quality ranged from poor (21, 25, 26, 32, 38, 43), moderate (12, 13, 20, 23, 24, 2831, 34, 36, 37, 3941, 44), to good (14, 22, 27, 42). Strengths across the studies included in-detail descriptions of the RTLS implementation in the residential setting. Common limitations were unclear recruitment processes, and not all studies documented how consent was obtained.

Review findings

The results of this scoping review are discussed under the following themes: levels of activity, characterization of wandering, cognition, social engagement, RTLS used to monitor health status or effect of an intervention, and other outcomes (Table 3). The table has been organized from publication date, highlighting how the focus of RTLS use in this population has changed over time.

TABLE 3
www.frontiersin.org

Table 3. Themes of RTLS use in older adults with dementia in residential living (by publication dates).

Compared to nursing documentation

In the earliest study in 2002, investigating the use of RTLS technology as a clinical tool, Chan et al. (40) validated the outputs of infra-red motion sensors against nursing documentation of a single patient across 39 nights. They identified that the nursing staff underestimated the patient’s nightly travel patterns, and the location data provided a more accurate assessment of resident activity. The ability of technology to provide a more precise description of a resident’s activity was supported by the work from Osaka, Japan (30, 31, 33). In this series of studies, the authors compared resident movement data to nursing observations, finding little agreement between location data and staff documentation.

Patterns of daily activity

Several studies have examined patterns of movement through the day, such as time spent outside of the bedroom or in shared spaces. For example, Bowen and Rowe (13) described the level of activity and activity variance between residents, reporting a high association between time spent away from room and institutionally scheduled routines, such as mealtimes. Residents with better walking abilities were observed to stay in common areas for extended periods and changed life-space areas less frequently. Those with inferior walking ability remained more often in their rooms. Grunerbl et al. (41) were also able to identify the daily activity habits of each participant, although they did not match these activities to walking ability. Grunerbl et al. (43) differentiated mobility patterns into social spaces according to the environment’s design. They determined that residents with rooms that open directly into social spaces had higher social withdrawal tendencies. Rooms farthest from social areas and those with no direct visibility to social areas were also associated with social withdrawal.

Other studies described daily activity patterns as they relate to an underlying diagnosis. Makimoto et al. (34) described the temporal activity patterns of several residents within a special dementia unit. They found that those with Alzheimer’s dementia had longer distances walked (mean 575 meters) compared to those with vascular dementia (mean 312 meters). Zhang et al. (29) tracked the activity of three residents as they recovered from COVID-19. They were able to demonstrate that sleep and motor abnormalities persisted in these residents for months after recovery compared to the baseline data which was obtained at the start of monitoring. For the first patient, the monitoring began on the day they returned from hospital (Day 11 after testing positive), the second patient’s monitoring began on Day 6, and the third on Day 0.

Characterization of wandering

Several studies of wandering have correlated location data to assessment tools used by nursing staff. Yayama et al. (30) identified that of the 23 Japanese Algase Wandering Scale (J-AWS) items, eight could be compared to movements measured by the monitoring technology. The temporal movements were compared to the first five items on the J-AWS, namely, the degree of restlessness throughout meal times, and spatial movements were compared to the pacing measurements. Residents rated as “wanderers” by staff had a longer distance walked per day than those rated as “non-wanderers.” The authors highlighted that staff assessment alone was likely insufficient to evaluate wandering behavior. They also found a poor correlation between night-time activity and staff J-AWS evaluation, although wandering through the night was a common occurrence. Bowen and Rowe (27) compared RTLS data to activities of daily living (ADL), measured by the Barthel index and the Functional Independence Measure, to assess the positive or negative effects of wandering on the ability to perform ADLs. This study found that an increased number of wandering episodes per week are associated with increased ability to perform ADLs. In contrast, an increased wandering distance was associated with a reduced ability to perform ADLs. Although Nakaoka et al. (37) did not compare data to a wandering tool, they used technology to characterize a resident’s pacing and lapping activities as a proportion of distance moved. They found the median number of pacing movements per day ranged from 2 to 52, with a high correlation to the median distance per day.

Two studies reported detailed mobility of one resident over time in an attempt to characterize wandering patterns. Greiner et al. (33) compared the movements of one resident’s wandering to observational records, finding that there was no pattern to his wandering, and caregivers had differing interpretations of the meaning of his wandering behaviors. Vahia et al. (26) compared location data on one resident over 70 days to nursing staff documentation. The data allowed them to identify patterns in levels of agitation as evidenced by night-time wandering and excessive pacing in the days following a family visit. Again, they found little agreement between nursing documentation and location data.

Association of mobility to levels of cognition

Three studies (20, 24, 25) link patterns in mobility to degree of cognitive impairment. They extracted various measures from location data over time (e.g., speed, path tortuosity) and examined the association between these features and cognitive impairment or dementia severity. A greater tortuosity (i.e., quantization of trajectory of a path with several turns) of the walking path predicted a higher level of cognitive impairment (20, 24, 25). Similarly, Bowen et al. (12) demonstrated that sustained gait speed was lower in those with severe cognitive impairment, and cognitive impairment was associated with longer but slower sustained walking.

Jansen et al. (14) used activity levels to determine that lower cognitive function is associated with more time away from their room. They hypothesized that those with lower levels of cognitive function and subsequent inability to independently way-find are often bound to stay in public areas longer.

Social interaction

There has been growing interest in using RTLS technology to measure degree of social interaction between nursing home residents. Grunerbl et al. (43) reported that the location data of those in a three-bedroom accommodation had the highest probability of being in a social space, while residents in a five-bedroom accommodation had a higher probability of being in a co-resident’s room. In a similar effort to quantify relationships between residents, Bellini et al. (39) developed the Relational Index and Popularity Index to quantify clusters of residents and close friendships within the community. They were able to demonstrate an objective change in the sociability pattern within the community during COVID-19 pandemic (Jan 2020-June 2020), where residents experienced longer times in isolation during the pandemic. Similarly, Okada et al. (32) used resident activity levels to calculate time spent in one’s room vs. shared spaces, on the assumption that residents who stay in the shared space or in other’s rooms are more socially active.

In addition to social interaction, Bowen et al. (28) demonstrated a unique clinical applicability of collecting social interaction data in the domain of infection prevention and control. This study reviewed movements of residents who were methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) positive, and were able to show that residents MRSA and VRE positive residents interacted with other residents (both positive and negative) regularly within the communal setting.

In terms of detecting negative interactions with co-residents, the study by Grunerbl et al. (41) identified episodes of aggressive behavior in one resident when they were near another resident. Other than describing the proximity and time together the residents, there are no studies examining the quality (e.g., resident behaviors signifying level of interest) of the social interactions.

Real-time location systems to monitor health status or effect of intervention

Multiple studies demonstrated how RTLS technology can be used to detect changes in a resident’s health status. Miyoshi et al. (36) explored the relationship between bodyweight and levels of activity. They were able to demonstrate weight gain in those with higher sedentary times, and weight loss in one resident who walked over 5 kilometers per day. The study by Grunerbl et al. (41) used UWB technology data to correlate location and a resident’s change in “broad classes of wellbeing” (positive or negative). A resident’s state of wellbeing was measured by the duration of stay in one area, the transition between areas, the ratio of the duration of stay and changes, and distribution over an area. They demonstrated that the technology could recognize a resident’s positive or negative state of wellbeing with improving accuracy over a more extended period (14 days). If a resident’s state of wellbeing fluctuated over the course of a day the prediction by the technology was not as accurate.

With UWB technology, Kearns et al. (23) demonstrated that a resident’s increased path tortuosity is associated with an increased risk of falling. Bowen and Rowe (13) also identified that walking patterns are associated with higher fall risk. Specifically, they identified residents who spend more time walking are at increased risk of falls. Bowen and Cacchione (22) used RTLS across two nursing homes and 23 residents for 18 months to examine whether mobility changes can be indicative of changes in health status. When reviewing average weekly motor behavior of the larger sample, residents with delirium walked farther (543 meters) and longer (35 min). Additionally, the authors identified that residents with an increased gait speed and continuous monthly decreases in physical and cognitive performance were most likely to experience a fall. Most recently Zhang et al. (29) used information derived from location data to describe changes in behavior (e.g., increased gait speed, increased activity levels) that were associated with recovery from COVID-19. They were also able to identify that one resident had worsening mobility and changes to sleep which may have been secondary to either experiencing COVID-19, or as a result of prolonged periods of isolation.

RTLS technology has also been used to monitor changes associated with medication administration. Liao et al. (38) used location data to provide descriptions of activity-based changes after a dose of brotizolam, notably a paradoxical increase in night-time wandering and daytime restlessness. In a case series, Au-Yeung et al. (21) demonstrated how passive IR technology can be used to detect changes in a resident’s behavior, leading to successful changes in medication treatments. In one scenario, the technology was used to identify that increasing sedentary times as a marker of decline in cognitive status. In a second case, the technology detected that a resident experienced an unusual motion signal during sleeping hours, which was identified as risperidone-induced periodic limb movements. They reduced the risperidone dose, leading to a resolution of the periodic limb movements.

In a case study, Okada et al. (32) used Integrated Circuit (IC) tag technology to demonstrate the impact of two interventions on the sleep-wake cycle. In the first intervention, they closed all doors within the unit, thereby increasing the resident’s daytime activity levels (decrease in the number of episodes of entering and napping in other resident rooms), which resulted in a significant decrease in night-time movement. The second intervention involved nurse-led mobility sessions, in which the resident resisted participation in the mobility sessions, contributing to increased agitation and night-time movements.

Finally, te Boekhorst et al. (42) implemented a GPS-based system as a restraint reduction intervention in residents at risk of elopement or falls. There was no significant effect of the system on the use of restraints (with a small number of restraints used overall), and no impact on resident quality of life.

Discussion

This scoping review has described how data from RTLS technologies have been used to support the clinical care of older adults with cognitive impairment in a residential care setting. While we also sought to identify validated RTLS-based clinical measures, we found few studies that have attempted this validation.

Most clinical use cases for this technology have focused on describing mobility or activity levels. Early studies compared RTLS data to nursing documentation and highlighted that these comparisons were difficult. An attempt was made to validate clinical wandering scales (e.g., RAWS-CV, J-AWS), but results were not promising secondary to low correlation between RTLS data and staff documentation. Residents are not constantly observed, and healthcare staff are not trained to detect changes in a resident’s gait, speed, or path. Thus, subjective staff assessments of a resident’s walking activity/wandering diverge substantially from the technology’s objective measure. Many patients with dementia may experience motor agitation (45), influencing patients to wander, and wandering is one of the most challenging care issues for people with dementia (46, 47). Given that clinician ratings so poorly capture the nature and extent of wandering, residents’ mobility and activity levels, it represents a promising target for RTLS technology.

Most recently, studies have focused on applying the data to describe social interaction for various purposes. From a systems perspective, data have been used to identify popular areas and traffic patterns within nursing homes, leading to the potential use of the data to aid in better nursing home design. There is a paucity of objective data that reports on the impact of environmental adaptations that may help to disguise exits or improve wayfinding within the unit. When examining resident interactions, authors have provided data on resident proximities, which was demonstrated to help trace communicable illnesses. However, there is little evidence available on the degree of interest, enjoyment or engagement of residents when they are in close proximity. There is potential for growth in this area, linking measurements of quality of resident interaction or social engagement to proximity data.

An under-explored area of research is the use of these technologies for evaluating residents’ psychological wellbeing. Jansen et al. (14) was the only study that specifically employed the Geriatric Depression Scale and Apathy Evaluation Scale. They identified that fewer depressive symptoms were significantly associated with more time away from a resident’s room. Cognitive impairment increases the risk for depressive symptoms (48, 49), and depression has been linked to increased sedentary time (50). Similarly, depression in nursing homes has been historically under-recognized and under-treated (51). Future studies that specifically examine the relationship between activity patterns and depression using similar scales would be helpful for clinicians. As an example, changes to level of activity may indicate a sign of depression. Pairing the technology findings with clinical assessments of mental health status may be beneficial to identify these potential relationships.

The body of literature reviewed in this study have provided multiple examples of the use of RTLS technology to aid in decision-making for resident care, mostly in case studies, with a dearth of clinical trials. However, some examples of objective data collection have immediate clinical applications. Miyoshi et al. (36) demonstrated that those who walk more are at greater risk of losing weight. Theirs was one of the first studies to objectively illustrate the impact of activity levels on weight change among residents with dementia. Clinicians may not easily estimate a resident’s energy requirements, as it is difficult to estimate the distances or levels of activity that residents are engaging in (52). Most recently, the case series by Peters et al. (18) and Kearns et al. (20) demonstrate how RTLS data can be used to direct medication treatments and better understand agitation triggers. With any case series studies, there is the limitation of generalizability of the data to other individuals and an over-interpretation of the data presented. However, the authors demonstrate a real-time clinical application of RTLS and how the data can subsequently be used to lead to optimal medication treatment.

There are several limitations within the body of work. Firstly, there is a lack of standardized assessments, which makes it difficult to compare results between papers (e.g., ADL and agitation scales differed between studies). None of the studies to date have successfully validated RTLS measures against a clinically important outcome or examined their diagnostic accuracy using receiver operating characteristic (ROC) curve analysis. As the quality of the evidence was overall poor to moderate, there were concerns related to sample size, inconsistent reporting of ethics, and descriptions of the datasets or the RTLS technology used. The duration of data collection varied widely. For example, Jansen et al. (14) collected data on 69 residents for only 2 days, whereas Bowen and Cacchione (22) collected data on 23 residents for 18 months. While there is some value in building evidence through case studies and observational studies, more extensive studies using population-level data in assisted living settings and advanced data science methods such as machine learning or deep learning, are needed.

Additionally, there are limitations to our scoping review process that are worth noting. First, scoping reviews have inherent limitations because the focus is to provide breadth rather than depth of information in a particular topic. This review provides a description of how RTLS technology is being used clinically in older adults with dementia living in residential care, and as such, the findings may not be applicable to other settings or populations. We also limited the review to studies in English, yet restricting reviews to English language publications appears to have little impact on conclusions of reviews (17).

Implications for practice and future research

Research into and clinical use of RTLS technology has increased substantially over the last twenty years, while many important questions remain to address. Interpreting the distance, speed or pattern of a resident’s movements over time in relation to their health and wellbeing is not a straightforward task. In the current state, much remains to be learned about extracting clinically meaningful insights from RTLS data. There is also a need for clinical evaluative studies about whether these objective measures can be used to influence decision-making to effect better patient outcomes. Moving forward, it will be necessary for researchers to validate these location-based measures against clinically important outcomes and consider how they can be used within clinical decision-making algorithms.

Author contributions

LH-L, LS, and AI performed the development of literature search protocol and contributed to text screening and data extraction. LH-L and LS performed initial analysis and compilation of results, and wrote the initial manuscript draft. CC, KM, CM, AF, SK, and AI performed review and editing. All authors have read and agreed to the published version of the manuscript.

Funding

This scoping review was completed to further projects funded by the AGE-WELL NCE (AWCRP-2020-02) and the Walter and Maria Schroeder Institute for Brain Innovation and Recovery.

Acknowledgments

We would like to acknowledge Jessica Babineau, MLIS information specialist from Toronto Rehabilitation Institute—University Health Network, for her assistance with the development and execution of the literature search.

Conflict of interest

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Supplementary material

The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1038008/full#supplementary-material

Footnotes

  1. ^ https://osf.io/3zny9/

References

1. Canadian Institute for Health Information. Dementia in Long-Term Care [Report]. (2022). Available online at: https://www.cihi.ca/en/dementia-in-canada/dementia-care-across-the-health-system/dementia-in-long-term-care (accessed November 1, 2022).

Google Scholar

2. Zimmerman S, Sloane PD, Heck E, Maslow K, Schulz R. Introduction: dementia care and quality of life in assisted living and nursing homes. Gerontologist. (2005) 45(suppl_1.):5–7. doi: 10.1093/geront/45.suppl_1.5

CrossRef Full Text | Google Scholar

3. Sloane PD, Zimmerman S, Suchindran C, Reed P, Wang L, Boustani M, et al. The public health impact of Alzheimer’s disease, 2000-2050: potential implication of treatment advances. Ann Rev Public Health. (2002) 23:213–31. doi: 10.1146/annurev.publhealth.23.100901.140525

PubMed Abstract | CrossRef Full Text | Google Scholar

4. Khan SS, Ye B, Taati B, Mihailidis A. Detecting agitation and aggression in people wth dementia using sensors - a systematic review. Alzheimers Dement. (2018) 14:824–32. doi: 10.1016/j.jalz.2018.02.004

PubMed Abstract | CrossRef Full Text | Google Scholar

5. Husebo B, Heintz H, Berge L, Owoyemi P, Rahman A, Vahia I. Sensing technology to monitor behavioral and psychological symptoms and to assess treatment response in people with dementia. a systematic review. Front Pharmacol. (2019) 10:1699. doi: 10.3389/fphar.2019.01699

PubMed Abstract | CrossRef Full Text | Google Scholar

6. Dolatabadi E, Van Ooteghem K, Taati B, Iaboni A. Quantitative mobility assessment for fall risk prediction in dementia: a systematic review. Dement Geriat Cogn Disord. (2018) 45:353–67. doi: 10.1159/000490850

PubMed Abstract | CrossRef Full Text | Google Scholar

7. Iersel MBV, Hoefsloot W, Munneke M, Bloem BR, Olde Rikkert MGM. Systematic review of quantitative clinical gait analysis in patients with dementia. Zeitschrift Für Gerontologie Und Geriatrie. (2004) 37:27–32. doi: 10.1007/s00391-004-0176-7

PubMed Abstract | CrossRef Full Text | Google Scholar

8. Taraldsen K, Chastin SFM, Riphagen II, Vereijken B, Helbostad JL. Physical activity monitoring by use of accelerometer-based body-worn sensors in older adults: a systematic literature review of current knowledge and applications. Maturitas. (2011) 71:13–9. doi: 10.1016/j.maturitas.2011.11.003

PubMed Abstract | CrossRef Full Text | Google Scholar

9. Lynn JD, Rondon-Sulbaran J, Quinn E, Ryan A, McCormack B, Martin S. A systematic review of electronic assistive technology within supporting living environments for people with dementia. Dementia. (2019) 18:2371–435. doi: 10.1177/1471301217733649

PubMed Abstract | CrossRef Full Text | Google Scholar

10. Kamel Boulos MN, Berry G. Real-time locating systems (RTLS) in healthcare: a condensed primer. Int J Health Geogr. (2012) 11:25. doi: 10.1186/1476-072X-11-25

PubMed Abstract | CrossRef Full Text | Google Scholar

11. Shum LC, Faieghi R, Borsook T, Faruk T, Kassam S, Nabavi H, et al. indoor location data for tracking human behaviours: a scoping review. Sensors. (2022) 22:1220. doi: 10.3390/s22031220

PubMed Abstract | CrossRef Full Text | Google Scholar

12. Bowen ME, Crenshaw J, Stanhope SJ. Balance ability and cognitive impairment influence sustained walking in an assisted living facility. Arch Gerontol Geriat. (2018) 77:133–41. doi: 10.1016/j.archger.2018.05.004

PubMed Abstract | CrossRef Full Text | Google Scholar

13. Bowen ME, Rowe M. Intraindividual changes in ambulation associated with falls in a population of vulnerable older adults in long-term care. Arch Phys Med Rehabilit. (2016) 97:1963–8. doi: 10.1016/j.apmr.2016.05.013

PubMed Abstract | CrossRef Full Text | Google Scholar

14. Jansen CP, Diegelmann M, Schnabel EL, Wahl HW, Hauer K. Life-space and movement behavior in nursing home residents: results of a new sensor-based assessment and associated factors. BMC Geriatr. (2017) 17:36. doi: 10.1186/s12877-017-0430-7

PubMed Abstract | CrossRef Full Text | Google Scholar

15. Akl A, Taati B, Mihailidis A. Autonomous unobtrusive detection of mild cognitive impairment in older adults. IEEE Trans Biomed Eng. (2015) 62:1383–94. doi: 10.1109/TBME.2015.2389149

PubMed Abstract | CrossRef Full Text | Google Scholar

16. Grigorovich A, Kulandaivelu Y, Newman K, Bianchi A, Khan SS, Iaboni A, et al. Factors affecting the implementation, use, and adoption of real-time location system technology for persons living with cognitive disabilities in long term care homes: systematic review. J Med Internet Res. (2021) 23:e22831. doi: 10.2196/22831

PubMed Abstract | CrossRef Full Text | Google Scholar

17. Dobrescu AI, Nussbaumer-Streit B, Klerings I, Wagner G, Persad E, Sommer I, et al. Restricting evidence syntheses of interventions to english-language publications is a viable methodological shortcut for most medical topics: a systematic review. J Clin Epidemiol. (2021) 137:209–17. doi: 10.1016/j.jclinepi.2021.04.012

PubMed Abstract | CrossRef Full Text | Google Scholar

18. Peters MDJ, Godfrey C, McInerney P, Munn Z, Tricco AC, Khalil H. Chapter 11: Scoping Reviews (2020 version). In: Aromataris E, Munn Z editors. JBI Manual for Evidence Synthesis. Adelaide: JBI (2020). p. 2020. doi: 10.4102/aosis.2020.BK85.07

PubMed Abstract | CrossRef Full Text | Google Scholar

19. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The Prisma 2020 statement: an updated guideline for reporting systematic reviews. BMJ. (2021) 372:n71. doi: 10.1136/bmj.n71

PubMed Abstract | CrossRef Full Text | Google Scholar

20. Kearns WD, Fozard JL, Nams VO, Craighead JD. Wireless telesurveillance system for detecting dementia. Gerontechnology. (2011) 10:90–102. doi: 10.4017/gt.2011.10.2.004.00

CrossRef Full Text | Google Scholar

21. Au-Yeung W-TM, Miller L, Beattie Z, May R, Cray HV, Kabelac Z, et al. Monitoring behaviors of patients with late-stage dementia using passive environmental sensing approaches: a case series. Am J Geriat Psychiatry. (2022) 30:1–11. doi: 10.1016/j.jagp.2021.04.008

PubMed Abstract | CrossRef Full Text | Google Scholar

22. Bowen ME, Cacchione P. Changes in motor behavior predict falls and identify acute events. West J Nurs Res. (2021) 1939459211031981. [Epub ahead of print]. doi: 10.1177/01939459211031981

PubMed Abstract | CrossRef Full Text | Google Scholar

23. Kearns WDP, Fozard JLP, Becker MRNP, Jasiewicz JMP, Craighead JDP, Holtsclaw LBA, et al. Path tortuosity in everyday movements of elderly persons increases fall prediction beyond knowledge of fall history, medication use, and standardized gait and balance assessments. J Am Med Direct Assoc. (2012) 13:665.e7–e13. doi: 10.1016/j.jamda.2012.06.010

PubMed Abstract | CrossRef Full Text | Google Scholar

24. Kearns WD, Nams VO, Fozard JL. Tortuosity in movement paths is related to cognitive impairment. Wireless fractal estimation in assisted living facility residents. Methods Inf Med. (2010) 49:592–8. doi: 10.3414/ME09-01-0079

PubMed Abstract | CrossRef Full Text | Google Scholar

25. Kumar A, Lau CT, Ma M, Chan S, Kearns W, editors. Trend Analysis in the Trajectory of the Dementia Patients2017. Bangkok: IEEE (2017). doi: 10.1109/ICSEC.2017.8443918

CrossRef Full Text | Google Scholar

26. Vahia IV, Kabelac Z, Hsu C-Y, Forester BP, Monette P, May R, et al. Radio signal sensing and signal processing to monitor behavioral symptoms in dementia: a case study. Am J Geriat Psychiatry. (2020) 28:820–5. doi: 10.1016/j.jagp.2020.02.012

PubMed Abstract | CrossRef Full Text | Google Scholar

27. Bowen ME, Rowe M. Wandering behavoiurs and activities of daily living among older adults with cognitive impairment. Rehabilitat Nurs. (2019) 44:282–9. doi: 10.1097/rnj.0000000000000148

PubMed Abstract | CrossRef Full Text | Google Scholar

28. Bowen ME, Craighead JD, Klanchar SA, Nieves-Garcia V. Multidrug-resistant organisms in a community living facility: tracking patient interactions and time spent in common areas. Am J Infect Control. (2012) 40:677–9. doi: 10.1016/j.ajic.2011.08.015

PubMed Abstract | CrossRef Full Text | Google Scholar

29. Zhang G, Vahia IV, Liu Y, Yang Y, May R, Cray HV, et al. Contactless in-home monitoring of the long-term respiratory and behavioral phenotypes in older adults with covid-19: a case series. Front Psychiatry. (2021) 12:754169. doi: 10.3389/fpsyt.2021.754169

PubMed Abstract | CrossRef Full Text | Google Scholar

30. Yayama S, Yamakawa M, Suto S, Greiner C, Shigenobu K, Makimoto K. Discrepancy between subjective and objective assessments of wandering behaviours in dementia as measured by the algase wandering scale and the integrated circuit tag monitoring system. Psychogeriatrics. (2013) 13:80–7. doi: 10.1111/psyg.12011

PubMed Abstract | CrossRef Full Text | Google Scholar

31. Yamakawa M, Suto S, Shigenobu K, Kunimoto K, Makimoto K. Comparing dementia patients’ nighttime objective movement indicators with staff observations. Psychogeriatrics. (2012) 12:18–26. doi: 10.1111/j.1479-8301.2011.00380.x

PubMed Abstract | CrossRef Full Text | Google Scholar

32. Okada S, Inoue K, Imai T, Noguchi M, Kuwamura K editors. Dementia Scale Classification Based on Ubiquitous Daily Activity and Interaction Sensing2019. Cambridge, UK: IEEE (2019). doi: 10.1109/ACII.2019.8925454

CrossRef Full Text | Google Scholar

33. Greiner C, Makimoto K, Suzuki M, Yamakawa M, Ashida N. Feasibility study of the integrated circuit tag monitoring system for dementia residents in Japan. Am J Alzheimer’s Dis Other Dement. (2007) 22:129–36. doi: 10.1177/1533317507299414

PubMed Abstract | CrossRef Full Text | Google Scholar

34. Makimoto K, Eun Ah L, Kang Y, Yamakawa M, Ashida N, Kyung Rim S. Temporal patterns of movements in institutionalized elderly with dementia during 12 consecutive days of observation in Seoul, Korea. Am J Alzheimer’s Dis Other Dement. (2008) 23:200–6. doi: 10.1177/1533317507312625

PubMed Abstract | CrossRef Full Text | Google Scholar

35. Yamakawa M, Shigenobu K, Makimoto K, Zhu C, Ashida N, Tabushi K. Environmental control interventions for frontotemporal dementia with reversed sleep-wake cycles. Am J Alzheimer’s Dis Other Dement. (2008) 23:470–6. doi: 10.1177/1533317508320087

PubMed Abstract | CrossRef Full Text | Google Scholar

36. Miyoshi R, Yamakawa M, Shigenobu K, Makimoto K, Zhu C, Segawa N, et al. Association between activity level and changes in bodyweight in dementia patients. Psychogeriatrics. (2008) 8:170–4. doi: 10.1111/j.1479-8301.2008.00244.x

CrossRef Full Text | Google Scholar

37. Nakaoka A, Suto S, Makimoto K, Yamakawa M, Shigenobu K, Tabushi K. Pacing and lapping movements among institutionalized patients with dementia. Am J Alzheimer’s Dis Other Dement. (2010) 25:167–72. doi: 10.1177/1533317509356688

PubMed Abstract | CrossRef Full Text | Google Scholar

38. Liao XY, Yamakawa M, Suto S, Shigenobu K, Makimoto K. Changes in activity patterns after the oral administration of brotizolam in institutionalized elderly patients with dementia: an observational case series study. Psychogeriatrics. (2012) 12:99–105. doi: 10.1111/j.1479-8301.2011.00401.x

PubMed Abstract | CrossRef Full Text | Google Scholar

39. Bellini G, Cipriano M, Comai S, De Angeli N, Gargano JP, Gianella M, et al. Understanding social behaviour in a health-care facility from localization data: a case study. Sensors. (2021) 21:2147. doi: 10.3390/s21062147

PubMed Abstract | CrossRef Full Text | Google Scholar

40. Chan M, Campo E, Laval E, Estève D. Validation of a remote monitoring system for the elderly: application to mobility measurements. Technol Health Care. (2002) 10:391–9. doi: 10.3233/THC-2002-10503

CrossRef Full Text | Google Scholar

41. Grunerbl A, Bahle G, Lukowicz P, Hanser F, editors. Using Indoor Location to Assess the State of Dementia Patients: Results and Experience Report from a Long Term, Real World Study2011. Nottingham, UK: IEEE (2011). doi: 10.1109/IE.2011.22

CrossRef Full Text | Google Scholar

42. te Boekhorst S, Depla MFIA, Francke AL, Twisk JWR, Zwijsen SA, Hertogh CMPM. Quality of life of nursing-home residents with dementia subject to surveillance technology versus physical restraints: an explorative study. Int J Geriat Psychiatry. (2013) 28:356–63. doi: 10.1002/gps.3831

PubMed Abstract | CrossRef Full Text | Google Scholar

43. Yang ACH, Lau N, Ho JCF. The role of bedroom privacy in social interaction among elderly residents in nursing homes: an exploratory case study of Hong Kong. Sensors. (2020) 20:4101. doi: 10.3390/s20154101

PubMed Abstract | CrossRef Full Text | Google Scholar

44. Grenier A, Griffin M, Andrews G, Wilton R, Burkec E, Ojembe B, et al. Meanings and feelings of (Im)mobility in later life: case study insights from a ‘New Mobilities’ perspective. J Aging Stud. (2019) 51:100819. doi: 10.1016/j.jaging.2019.100819

PubMed Abstract | CrossRef Full Text | Google Scholar

45. Steinberg M, Shao H, Zandi P, Lyketsos CG, Welsh-Bohmer KA, Norton MC, et al. Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the cache county study. Int J Geriatr Psychiatry. (2008) 23:170–7. doi: 10.1002/gps.1858

PubMed Abstract | CrossRef Full Text | Google Scholar

46. Matsumoto N, Ikeda M, Fukuhara R, Shinagawa S, Ishikawa T, Mori T, et al. Caregiver burden associated with behavioral and psychological symptoms of dementia in elderly people in the local community. Dement Geriat Cogn Disord. (2007) 23:219–24. doi: 10.1159/000099472

PubMed Abstract | CrossRef Full Text | Google Scholar

47. Neil W, Bowie P. Carer burden in dementia-assessing the impact of behavioural and psychological symptoms via self-report questionnaire. Int J Geriat Psychiatry. (2008) 23:60–4. doi: 10.1002/gps.1839

PubMed Abstract | CrossRef Full Text | Google Scholar

48. Hoben M, Heninger A, Holroyd-Leduc J, Knopp-Sihota J, Estabrooks C, Goodarzi Z. Depressive symptoms in long term care facilities in Western Canada: a cross sectional study. BMC Geriat. (2019) 19:335. doi: 10.1186/s12877-019-1298-5

PubMed Abstract | CrossRef Full Text | Google Scholar

49. Chu CH, Quan AML, McGilton KS. Depression and functional mobility decline in long term care home residents with dementia: a prospective cohort study. Can Geriat J. (2021) 24:325–31. doi: 10.5770/cgj.24.511

PubMed Abstract | CrossRef Full Text | Google Scholar

50. Maasakkers CM, Claassen JAHR, Scarlett S, Thijssen DHJ, Kenny RA, Feeney J, et al. Is there a bidirectional association between sedentary behaviour and cognitive decline in older adults? Findings from the irish longitudinal study on ageing. Prevent Med Rep. (2021) 23:101423. doi: 10.1016/j.pmedr.2021.101423

PubMed Abstract | CrossRef Full Text | Google Scholar

51. Simning A, Simons KV. Treatment of depression in nursing home residents without significant cognitive impairment: a systematic review. Int Psychogeriatr. (2017) 29:209–26. doi: 10.1017/S1041610216001733

PubMed Abstract | CrossRef Full Text | Google Scholar

52. Poehlman ET, Dvorak RV. Energy expenditure, energy intake, and weight loss in Alzheimer disease. Am J Clin Nutr. (2000) 71:650S–5S. doi: 10.1093/ajcn/71.2.650s

PubMed Abstract | CrossRef Full Text | Google Scholar

Keywords: RTLS (Real-time location system), cognitive impairment, dementia, older adults, residential care, long-term care, remote monitoring, wearable technological device

Citation: Haslam-Larmer L, Shum L, Chu CH, McGilton K, McArthur C, Flint AJ, Khan S and Iaboni A (2022) Real-time location systems technology in the care of older adults with cognitive impairment living in residential care: A scoping review. Front. Psychiatry 13:1038008. doi: 10.3389/fpsyt.2022.1038008

Received: 06 September 2022; Accepted: 24 October 2022;
Published: 10 November 2022.

Edited by:

Alexandra König, Research Centre Inria Sophia Antipolis Méditerranée, France

Reviewed by:

Nele A. J. De Witte, Thomas More University of Applied Sciences, Belgium
Neda Firouraghi, Mashhad University of Medical Sciences, Iran

Copyright © 2022 Haslam-Larmer, Shum, Chu, McGilton, McArthur, Flint, Khan and Iaboni. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Andrea Iaboni, YW5kcmVhLmlhYm9uaUB1aG4uY2E=

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.