Long Non-Coding RNA SNHG1 Regulates the Wnt/β-Catenin and PI3K/AKT/mTOR Signaling Pathways via EZH2 to Affect the Proliferation, Apoptosis, and Autophagy of Prostate Cancer Cell
- 1Department of Urology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China
- 2Department of Urology, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China
- 3Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
By Chen J, Wang F, Xu H, Xu L, Chen D, Wang J, Huang S, Wen Y and Fang L (2020). Front. Oncol. 10:552907. doi: 10.3389/fonc.2020.552907
In the published article, there was an error in Figures 4, 5 as published. Due to the failure to replace the latest figures during repair and the proof not being thoroughly checked, errors were found in Figures 4, 5. The corrected Figures 4, 5 and its caption appear below.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Figure 4. Regulatory effect of SNHG1 on the migration and invasion of PCa cells by targeting EZH2. Transwell assay detected thel migration and invasion of LNCaP and PC3 cells transfected with NC, si-SNHG1, si-EZH2, si-SNHG1+con, si-SNHG1+EZH2. **P < 0.01 vs. NC group; ##P < 0.01 vs. si-SNHG1 + con group.
Figure 5. Effect of SNHG1 binding EZH2 on autophagy in LNCap and PC-3 cells. (A, B) Immunofluorescence staining detected the formation of the LC3 spots with the interference of SNHG1 in LNCaP and PC3 cells and the down-regulation of EZH2 or the interference of SNHG1 and simultaneous overexpression of EZH2. (C) Western blot detected the expression level of autophagy-related proteins LC3-II, Beclin-1 and P62 protein in LNCaP and PC3 cells transfected with NC, si-SNHG1, si-EZH2, si-SNHG1+con, si-SNHG1+EZH2.
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Keywords: prostate cancer, long-chain non-coding RNA, cell viability, apoptosis, autophagy
Citation: Chen J, Wang F, Xu H, Xu L, Chen D, Wang J, Huang S, Wen Y and Fang L (2024) Corrigendum: Long non-coding RNA SNHG1 regulates the Wnt/β-catenin and PI3K/AKT/mTOR signaling pathways via EZH2 to affect the proliferation, apoptosis, and autophagy of prostate cancer cell. Front. Oncol. 14:1501882. doi: 10.3389/fonc.2024.1501882
Received: 25 September 2024; Accepted: 27 October 2024;
Published: 25 November 2024.
Edited and Reviewed by:
Olivier Feron, Université catholique de Louvain, BelgiumCopyright © 2024 Chen, Wang, Xu, Xu, Chen, Wang, Huang, Wen and Fang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Junyi Chen, Y2hlbmp1bnlpZG9jdG9yQDE2My5jb20=
†These authors have contributed equally to this work