Santiago A. Plano
Sebastián Soneira3
Camila Tortello
Diego A. Golombek- 1Institute for Biomedical Research (BIOMED), National Scientific and Technical Research Council (CONICET), Catholic University of Argentina (UCA), Buenos Aires, Argentina
- 2Laboratorio de Cronobiología, Universidad Nacional de Quilmes/CONICET, Buenos Aires, Argentina
- 3Sección de Trastornos de la Conducta Alimentaria y Psiquiatría Nutricional, Servicio de Psiquiatría, FLENI, Buenos Aires, Argentina
- 4Escuela de Educación, Universidad de San Andrés, Buenos Aires, Argentina
Introduction
There is a wide range of eating disorders (EDs) which span from restrictive eating patterns such as anorexia nervosa, to the compulsive eating spectrum such as bulimia nervosa (BN), night-eating syndrome (NES), and binge-eating disorder (BED), all with complex multifactorial pathogenesis including biological, environmental, and psychological factors. In general, EDs enclosed within the compulsive spectrum include disordered bouts of feeding at different times of the day. Many aspects of these disorders are modulated by the circadian system, such as meal timing, mood, compulsive behavior, and sleep quality.
We conducted a systematic search combining binge eating studies with circadian/sleep analyses to assess the main aspects of the BED and its relationship with the circadian system. This was conducted on the electronic database MEDLINE/PubMed using the search string (binge eating) AND [(circadian) or (rhythm)]. We searched the literature references to find additional articles. We kept only the papers that treat binge eating as a disorder and not as a component of other disorders, such as the binge eating episodes in bulimia nervosa. In view of the scarce literature on the subject, here we propose a call to action for examining circadian patterns in more detail within BED.
Binge eating disorder (BED)
Binge eating disorder (BED) is the most frequent eating disorder, affecting 1–3% of the population, with onset between 15.5–27.2 years of age and an average duration of 4–8 years (1, 2). Like most eating disorders, BED is more common in women (3.5%) vs. men (2.0%) (2). Despite being the most common eating disorder, many patients fail to receive a proper diagnosis or do. Indeed, in a representative sample of American adults, only 3.2% of respondents who met DSM-5 criteria for BED had received an appropriate formal diagnosis in the previous 12 months (3). Originally described by Spitzer (4), BED is characterized by the presence of recurrent binge-eating episodes with a minimum duration of 3 months and a frequency of > once a week. Another important fact to consider is the unpleasant nature of binge eating and the absence of purging behaviors or subsequent compensation.
An episode of binge eating is characterized by the ingestion of more food than what most people would eat in a similar period and circumstances, as well as a feeling of lack of control over what is ingested. Its clinical description represents a specific eating disorder, different from other mental disorders after its inclusion in 2013 in DSM-5 (5). The differential diagnoses of this disorder include Bulimia Nervosa (BN), the binge-eating and purging subtype of Anorexia Nervosa (BP-AN), and night eating syndrome (NES).
In BN, episodes of binge eating are usually followed by self-induced purging behaviors (generally vomiting). In BP-AN, the same thing happens, but body weight is noticeably decreased due to the intense restriction of meals. In both disorders, an intense fear of gaining weight is clearly present. Finally, the NES is characterized by recurring episodes of food intake at night, manifested by eating when waking up during the night or by excessive consumption of food after dinner (6). Clearly, in the NES the most important factor is the time of day in which the ingestion occurs. Described in the 1950s, the chronobiological aspects of NES have received more consideration: NES patients tend to express evening chronotype with a higher frequency of insomnia and overweight conditions (41, 42).
Patients with BED present a high prevalence of psychiatric and physical comorbidities. Between 30.0 and 80.0% of individuals with BED present lifetime comorbid mood and anxiety disorders (7, 8). Other common comorbidities reported in individuals with BED comprise numerous addiction disorders such as substance use/abuse (22.0%) (9), gambling problems (5.7–18.7%) (10) as well as compulsive buying (7.4–18.5%) (11).
The prevalence of binge eating disorder in individuals with obesity attending weight loss programs was found to be between 16–52% (12).
Individuals with obesity and comorbid eating disorders are at high risk of several medical and psychosocial complications such as diabetes, hypertension, and chronic pain (1, 13). A study with 152 treatment-seeking individuals with obesity found that those with binge eating disorder had higher BMIs, more severe levels of depression and obsessive-compulsive symptoms, and stronger feelings of inadequacy and inferiority than those without binge eating disorder (14).
Chronotype and chrono-nutrition
Humans differ in their preferences for activity and sleep patterns during the day, reflecting interindividual differences in their daily physiological organization, defining morning and evening chronotypes (15, 16).
There is a clear association between mood and chronotypes (17, 18). In particular, the eveningness dimension could be considered a vulnerability factor to depressive symptoms and Major Depressive Disorder (19).
Different studies investigated the relationship between personality traits and chronotypes (20); evening types were associated with anxious, hostile, impulsive and depressive personality traits, while a morning chronotype was associated with traits such as conscientiousness and with the tendency to be compliant (21, 22).
The term chrono-nutrition refers to energy distribution processes including feeding-fasting rhythm, meal frequency, the duration of the eating period, and the relationship with metabolic health (23, 24). Meal regularity establishes the pattern of energy intake and distribution, which is crucial for health outcomes. On the other hand, meal irregularity, defined as food consumption at different times and in varying amounts throughout the day (25), is associated with obesity and metabolic-related disease (26). Several recent studies indicate that food intake at later times is highly associated with increased adiposity, obesity, and metabolic risk (26, 27). Moreover, eating a large amount of food during the evening increased the odds of obesity and metabolic syndrome (28). An increased ratio of evening-to-morning meals has been associated with an increase in the body mass index (BMI), while a higher morning-to-evening ratio has the opposite effect (29–31). The conclusion is that eating when the body is not ready to manage a large amount of energy (i.e., when we are preparing to sleep), has a great impact on our health (28). The proximity of food consumption to the nocturnal rise of melatonin was associated with impaired glucose homeostasis and increased adiposity (32, 33). Eating behavior has been linked to circadian rhythms (34), since clock genes may synchronize not only the feeding-fasting rhythm but also metabolism itself (35, 36). In this sense, the individual differences in chronotype could influence eating behavior as a zeitgeber (37). For instance, late chronotype or late mealtime were associated with an increased desire for high-fat foods and more appetite (38).
The relationship between the circadian system and specific eating disorders remains unclear in part, this may be due to nosographic aspects related to the diagnostic systems of EDs, particularly regarding the differential diagnoses between BED and NES.
Although NES is described as an eating disorder in the DSM, many authors have questioned its validity as a nosographic construct (39, 40), even when it represents the most relevant results associated with eating at night and its consequences. Individuals with BED or NES share the feeling of a loss of control over food consumption, but both syndromes differ in their timing. Several studies demonstrate that energy intake in NES patients tended to occur during the night, affecting the sleep-wake cycle (41, 42). In contrast, in BED patients, the available literature fails to systematically collect and inform the time of the binge behavior that may occur at any time of the day (43, 44). Only a few studies report circadian preferences in patients with eating disorders (37, 40, 45). A circadian approach to the BED indicated that subjects with either BED or NES were more likely to have an evening chronotype (40), as well as higher rates of anxious and depressive symptoms. Subjects with NES have similar sleep onset and offset times to those of controls (46, 47), suggesting that their delay in chronotype may be due to their eating behavior and not to the circadian system. Indeed, more work is needed to examine when binge episodes occur and what is their relationship with the feeding-fasting rhythm, the subject's chronotype. Social aspects should also be considered, e.g., if the binge occurs when people are alone, or if there is some preference for binge during week-days or during weekends which can contribute to social jetlag, another circadian disruption with metabolic consequences. In this sense, both NES and BED can act as a promotor of- as well as a consequence of- circadian disruption, inducing a vicious cycle between both alterations.
Binge behavior and sleep
Sleep disturbances has been studied in patients with NES, which tend to present insomnia and periodic limb movements. Moreover, night eaters reported higher ratings of sleep perturbations and use of sleep medications (41). However, NES was not associated with day-time sleepiness. A rest-activity pattern study found no differences on sleep-onset time or total sleep duration in NES, although more awakenings and later sleep offset time have been reported (41).
A study of the rest-activity pattern in patients with BED demonstrated some alterations in their circadian behavior. BED patients exhibited a lower MESOR (mean estimate of circadian rhythm, derived from fitting the data to a cosine wave) and amplitude than control subjects (48). Patients also presented low sleep-efficiency values, but this was also present in an obese control group, indicating that it could be ascribed to overweight conditions (45). Different studies analyzing obese patients with and without BED confirmed this finding: sleep architecture abnormalities in patients with BED were also found in the obese control group (45). Despite this, another study demonstrated that BED patients show more minutes of wakefulness during the sleep period than normal-weight controls (49), presumably due to their binge episodes. In addition, significantly higher sleep-disruption parameters were found in children with BED than in obese non-BED and normal-weight controls (49). More work needs to be done to clarify the relationship between BED and the circadian pattern of sleep, sleep quality, and its dependence on obesity.
Addictive-like eating behaviors
Binge eating disorder is recognized as an eating disorder involving compulsive food intake. Some authors point out that this type of behavior could be included within a theoretical construct called Food Addiction (FA) (50, 51), employed to describe addictive-like compulsive overeating which involves cravings and difficulties in abstaining from high-calorie foods (52). Even though FA could be present in patients with BED, it is important to note that while BED is a classified and diagnosable mental disorder, FA remains a controversial concept that has not yet been recognized as a diagnostic entity. FA shows some similarities with substance abuse disorders; indeed, both drug consumption and excessive food intake share neural changes in the brain reward system (53–56). Dopaminergic activity disruption appears to be a common root for drug intake and compulsive eating, supporting the food addiction concept (57).
As we mentioned, feeding is rhythmically distributed over a 24h period (58). Interestingly, a circadian rhythm for caloric intake has also been described (59–61); and, in accordance, a binge eating behavior rhythm was found in rats with an increase in dopamine receptor density in the nucleus accumbens (62). This “caloric preference” rhythm is regulated by the circadian system (59, 63–65), while its hedonic component depends on the rhythmic activity of DA, which in rodents peaks at night, corresponding with their nocturnal phase of activity and food consumption (66, 67). This DA release in the striatum depends on the circadian-controlled VTA rhythmic activity (68, 69). Indeed, more information is needed on the relationship between feeding and reward rhythms in humans.
There is also a correlation between chronotype and food preference: an evening chronotype is correlated with greater consumption of high calorie-beverages, caffeine, alcohol, nicotine, and fast food (70–72), and lower consumption of fruit, vegetables, and fish (73). Moreover, subjects with an evening type show a higher energy intake at night, and this effect was even larger during weekends (71, 74). The metabolic and hedonic regulation of feeding is rhythmic and depends on the circadian system; the timing of food consumption is crucial for the regulation of food intake, and the loss of this circadian pattern might lead to disorders that display compulsive eating, obesity, and metabolic syndrome as a part of its symptomatic complex (75).
Conclusion
In this work, we focused on the literature exploring the main physiological aspects controlled by the circadian system that affect or are affected by the binge eating disorder, and how the circadian system may play a significant role in the development of more severe outcomes. We summarize the current state of the literature studying the circadian aspects of BED, to find out that is a topic yet to be explored and offer our suggestions for future research in BED to include designs capable of collecting sufficient and necessary information to study the role of the circadian system on the BED progression. The circadian system modulates different aspects of mood and mood-related behavior, including emotion, compulsive behavior, and regulatory control (76). All these features are in close relationship with BED and should be studied from a circadian perspective. Given the higher prevalence of BED in women, it would also be important to delve into the influence of neurohormonal systems in the genesis of the disorder and its relationship with biological rhythms.
One of the main difficulties to study circadian aspects of BED is the differential diagnostic overlapping between BED and NES. Food is a strong signal for the circadian system; both BED and NES alter the feeding-fasting rhythm causing a circadian disruption which, in turn, will affect feeding, creating a vicious cycle of important consequences for the patient's well-being. In this sense NES and BED can be consequence of- or promotor of- a circadian disruption and an evening chronotype. Future studies need to address the crosstalk between BED, NES and the circadian system, including some objective measures of sleep-wake cycle, circadian status and energy consumption, as well as some subjective measures to cover aspects related to sleep and chronotype. In this sense, the mechanisms behind binge timing, mood, compulsive behavior, and sleep alteration need to be acknowledged to create a more accurate BED vs. NES diagnosis.
Author contributions
All authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication.
Funding
The studies in authors' laboratories were funded by the Universidad Nacional de Quilmes, CONICET and the National Science Agency (ANPCyT), Argentina.
Conflict of interest
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Publisher's note
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References
1. Kessler RC, Berglund PA, Chiu WT, Deitz AC, Hudson JI, Shahly V, et al. The prevalence and correlates of binge eating disorder in the world health organization world mental health surveys. Biol Psychiatry. (2013) 73:904–14. doi: 10.1016/j.biopsych.2012.11.020
2. Hudson JI, Hiripi E, Pope HG Jr, Kessler RC The prevalence and correlates of eating disorders in the national comorbidity survey replication. Biol Psychiatry. (2007) 61:348–58. doi: 10.1016/j.biopsych.2006.03.040
3. Cossrow N, Pawaskar M, Witt EA, Ming EE, Victor TW, Herman BK, et al. Estimating the prevalence of binge eating disorder in a community sample from the United States: comparing Dsm-Iv-Tr and Dsm-5 criteria. J Clin Psychiatry. (2016) 77:e968–74. doi: 10.4088/JCP.15m10059
4. Spitzer RL, Yanovski S, Wadden T, Wing R, Marcus MD, Stunkard A, et al. Binge eating disorder: its further validation in a multisite study. Int J Eat Disord. (1993) 13:137–53. doi: 10.1002/1098-108X(199303)13:2<137::AID-EAT2260130202>3.0.CO;2-%23
6. Allison KC, Lundgren JD, O'Reardon JP, Geliebter A, Gluck ME, Vinai P, et al. Proposed diagnostic criteria for night eating syndrome. Int J Eat Disord. (2010) 43:241–7. doi: 10.1002/eat.20693
7. McElroy SL, Crow S, Blom TJ, Biernacka JM, Winham SJ, Geske J, et al. Prevalence and correlates of Dsm-5 eating disorders in patients with bipolar disorder. J Affect Disord. (2016) 191:216–21. doi: 10.1016/j.jad.2015.11.010
8. Udo T, Grilo CM. Psychiatric and medical correlates of Dsm-5 eating disorders in a nationally representative sample of adults in the United States. Int J Eat Disord. (2019) 52:42–50. doi: 10.1002/eat.23004
9. Villarejo C, Fernández-Aranda F, Jiménez-Murcia S, Peñas-Lledó E, Granero R, Penelo E, et al. Lifetime obesity in patients with eating disorders: increasing prevalence, clinical and personality correlates. Eur Eat Disord Rev. (2012) 20:250–4. doi: 10.1002/erv.2166
10. Hsu L, Mulliken B, McDonagh B, Krupa Das S, Rand W, Fairburn C, et al. Binge eating disorder in extreme obesity. Int J Obes. (2002) 26:1398–403. doi: 10.1038/sj.ijo.0802081
11. Striegel RH, Bedrosian R, Wang C. Comparing work productivity in obesity and binge eating. Int J Eat Disord. (2012) 45:995–8. doi: 10.1002/eat.22069
12. Palavras MA, Kaio GH. Mari JdJ, Claudino AM. A review of latin american studies on binge eating disorder Brazilian. J Psychiatry. (2011) 33:s81–94. doi: 10.1590/S1516-44462011000500007
13. Roehrig M, Masheb RM, White MA, Grilo CM. The metabolic syndrome and behavioral correlates in obese patients with binge eating disorder. Obesity. (2009) 17:481–6. doi: 10.1038/oby.2008.560
14. Poli R, Maninetti L, Bodini P, Agrimi E. Obesity, binge eating, obstruction sleep apnea and psychopathological features. Clin Neuropsychiatry. (2012) 9:166–71.
15. Horne JA, Östberg O. A Self-Assessment questionnaire to determine morningness-eveningness in human circadian rhythms. Int J Chronobiol. (1976) 4:97–110
16. Roenneberg T, Kuehnle T, Juda M, Kantermann T, Allebrandt K, Gordijn M, et al. Epidemiology of the human circadian clock. Sleep Med Rev. (2007) 11:429–38. doi: 10.1016/j.smrv.2007.07.005
17. Natale V, Adan A, Scapellato P. Are seasonality of mood and eveningness closely associated? Psychiatry Res. (2005) 136:51–60. doi: 10.1016/j.psychres.2004.12.010
18. Hirata FC, Lima MCO, de Bruin VMS, Nóbrega PR, Wenceslau GP, de Bruin PFC. Depression in medical school: the influence of morningness-eveningness. Chronobiol Int. (2007) 24:939–46. doi: 10.1080/07420520701657730
19. Bersani G, Bersani FS, Prinzivalli E, Limpido L, Marconi D, Valeriani G, et al. Premorbid circadian profile of patients with major depression and panic disorder. Riv Psichiatr. (2012) 47:407–12.
20. Tirassa P, Iannitelli A, Sornelli F, Cirulli F, Mazza M, Calza A, et al. Daily serum and salivary Bdnf levels correlate with morning-evening personality type in women and are affected by light therapy. Riv Psichiatr. (2012) 47:527–34. doi: 10.1708/1178.13059
21. Tonetti L, Fabbri M, Natale V. Relationship between circadian typology and big five personality domains. Chronobiol Int. (2009) 26:337–47. doi: 10.1080/07420520902750995
22. Lee K, Lee H-K, Jhung K, Park JY. Relationship between chronotype and temperament/character among university students. Psychiatry Res. (2017) 251:63–8. doi: 10.1016/j.psychres.2017.01.071
23. Johnston JD, Ordovás JM, Scheer FA, Turek FW. Circadian rhythms, metabolism, and chrononutrition in rodents and humans. Advan Nutr. (2016) 7:399–406. doi: 10.3945/an.115.010777
24. West AC, Bechtold DA. The cost of circadian desynchrony: evidence, insights and open questions. Bioessays. (2015) 37:777–88. doi: 10.1002/bies.201400173
25. Pot GK, Almoosawi S, Stephen AM. Meal irregularity and cardiometabolic consequences: results from observational and intervention studies. Proc Nutr Soc. (2016) 75:475–86. doi: 10.1017/S0029665116000239
26. Pot GK, Hardy R, Stephen AM. Irregular consumption of energy intake in meals is associated with a higher cardiometabolic risk in adults of a british birth cohort. Int J Obes. (2014) 38:1518–24. doi: 10.1038/ijo.2014.51
27. Xiao Q, Garaulet M, Scheer FA. Meal timing and obesity: interactions with macronutrient intake and chronotype. Int J Obes. (2019) 43:1701–11. doi: 10.1038/s41366-018-0284-x
28. Flanagan A, Bechtold DA, Pot GK, Johnston JD. Chrono-Nutrition: from molecular and neuronal mechanisms to human epidemiology and timed feeding patterns. J Neurochem. (2021) 157:53–72. doi: 10.1111/jnc.15246
29. Aljuraiban GS, Chan Q, Griep LMO, Brown IJ, Daviglus ML, Stamler J, et al. The impact of eating frequency and time of intake on nutrient quality and body mass index: the intermap study, a population-based study. J Acad Nutr Diet. (2015) 115:528–36. e1. doi: 10.1016/j.jand.2014.11.017
30. Kahleova H, Lloren JI, Mashchak A, Hill M, Fraser GE. Meal frequency and timing are associated with changes in body mass index in adventist health study 2. J Nutr. (2017) 147:1722–8. doi: 10.3945/jn.116.244749
31. Wang J, Patterson R, Ang A, Emond J, Shetty N, Arab L. Timing of energy intake during the day is associated with the risk of obesity in adults. J Hum Nutr Diet. (2014) 27:255–62. doi: 10.1111/jhn.12141
32. McHill AW, Czeisler CA, Phillips AJ, Keating L, Barger LK, Garaulet M, et al. Caloric and macronutrient intake differ with circadian phase and between lean and overweight young adults. Nutrients. (2019) 11:587. doi: 10.3390/nu11030587
33. McHill AW, Phillips AJ, Czeisler CA, Keating L, Yee K, Barger LK, et al. Later circadian timing of food intake is associated with increased body fat. Am J Clin Nutr. (2017) 106:1213–9. doi: 10.3945/ajcn.117.161588
34. Garaulet M, Madrid JA. Chronobiological aspects of nutrition, metabolic syndrome and obesity. Adv Drug Deliv Rev. (2010) 62:967–78. doi: 10.1016/j.addr.2010.05.005
35. Froy O. The relationship between nutrition and circadian rhythms in mammals. Front Neuroendocrinol. (2007) 28:61–71. doi: 10.1016/j.yfrne.2007.03.001
36. Sato-Mito N, Sasaki S, Murakami K, Okubo H, Takahashi Y, Shibata S, et al. The midpoint of sleep is associated with dietary intake and dietary behavior among young japanese women. Sleep Med. (2011) 12:289–94. doi: 10.1016/j.sleep.2010.09.012
37. Natale V, Ballardini D, Schumann R, Mencarelli C, Magelli V. Morningness–Eveningness preference and eating disorders. Pers Individ Dif. (2008) 45:549–53. doi: 10.1016/j.paid.2008.06.014
38. Beaulieu K, Oustric P, Alkahtani S, Alhussain M, Pedersen H, Quist JS, et al. Impact of meal timing and chronotype on food reward and appetite control in young adults. Nutrients. (2020) 12:1506. doi: 10.3390/nu12051506
39. Striegel-Moore RH, Franko DL, Garcia J. The validity and clinical utility of night eating syndrome. Int J Eat Disord. (2009) 42:720–38. doi: 10.1002/eat.20721
40. Harb A, Levandovski R, Oliveira C, Caumo W, Allison KC, Stunkard A, et al. Night eating patterns and chronotypes: a correlation with binge eating behaviors. Psychiatry Res. (2012) 200:489–93. doi: 10.1016/j.psychres.2012.07.004
41. Allison KC, Spaeth A, Hopkins CM. Sleep and eating disorders. Curr Psychiatry Rep. (2016) 18:92. doi: 10.1007/s11920-016-0728-8
42. Shoar S, Naderan M, Mahmoodzadeh H, Shoar N, Lotfi D. Night eating syndrome: a psychiatric disease, a sleep disorder, a delayed circadian eating rhythm, and/or a metabolic condition? Expert Rev Endocrinol Metab. (2019) 14:351–8. doi: 10.1080/17446651.2019.1657006
43. Aronoff NJ, Geliebter A, Hashim SA, Zaimmit GK. The relationship between daytime and nighttime food intake in an obese night-eater. Obes Res. (1994) 2:145–51. doi: 10.1002/j.1550-8528.1994.tb00640.x
44. Allison KC, Crow SJ, Reeves RR, West DS, Foreyt JP, DiLillo VG, et al. Binge eating disorder and night eating syndrome in adults with type 2 diabetes. Obesity. (2007) 15:1287–93. doi: 10.1038/oby.2007.150
45. Roveda E, Montaruli A, Galasso L, Pesenti C, Bruno E, Pasanisi P, et al. Rest-Activity circadian rhythm and sleep quality in patients with binge eating disorder. Chronobiol Int. (2018) 35:198–207. doi: 10.1080/07420528.2017.1392549
46. Ringel JP. Dinges DF, Allison KC, Rogers NL, Martino NS, et al. Circadian Eating and Sleeping Patterns in the Night Eating Syndrome. Obes Res. (2004) 12:1789–96. doi: 10.1038/oby.2004.222
47. Rogers NL, Dinges DF, Allison KC, Maislin G, Martino N, O'Reardon JP, et al. Assessment of sleep in women with night eating syndrome. Sleep. (2006) 29:814–9. doi: 10.1093/sleep/29.6.814
48. Galasso L, Montaruli A, Mulè A, Castelli L, Bruno E, Caumo A, et al. The multidisciplinary therapy in binge eating disorder is able to influence the interdaily stability and sleep quality? Chronobiol Int. (2019) 36:1311–5. doi: 10.1080/07420528.2019.1650059
49. Tzischinsky O, Latzer Y. Sleep–Wake cycles in obese children with and without binge-eating episodes. J Paediatr Child Health. (2006) 42:688–93. doi: 10.1111/j.1440-1754.2006.00952.x
50. Burrows T, Skinner J, McKenna R, Rollo M. Food addiction, binge eating disorder, and obesity: is there a relationship? Behav Sci. (2017) 7:54. doi: 10.3390/bs7030054
51. Wilfley DE, Bishop ME, Wilson GT, Agras WS. Classification of Eating Disorders: Toward Dsm-V. Int J Eat Disord. (2007) 40:S123–S9. doi: 10.1002/eat.20436
52. N Gearhardt A, White M, Potenza N. Binge eating disorder and food addiction. Current drug Abuse Rev. (2011) 4:201–7. doi: 10.2174/1874473711104030201
53. Avena NM. Food and addiction: implications and relevance to eating disorders and obesity. Curr Drug Abuse Rev. (2011) 4:131–2. doi: 10.2174/1874473711104030131
54. DiLeone RJ, Taylor JR, Picciotto MR. The drive to eat: comparisons and distinctions between mechanisms of food reward and drug addiction. Nat Neurosci. (2012) 15:1330–5. doi: 10.1038/nn.3202
55. Volkow ND, Wang G-J, Fowler JS, Tomasi D, Baler R. Food and drug reward: overlapping circuits in human obesity and addiction. In: Carter C, Dalley J, editors. Brain Imag Behav Neurosci. Current Topics in Behavioral Neurosciences, Vol. 11. Berlin: Springer. (2011). p. 1-24. doi: 10.1007/7854_2011_169
56. Volkow ND, Wise RA, Baler R. The dopamine motive system: implications for drug and food addiction. Nat Rev Neurosci. (2017) 18:741–52. doi: 10.1038/nrn.2017.130
57. Volkow ND, O'Brien CP. Issues for Dsm-V: should obesity be included as a brain disorder. Am Psychiatric Assoc. (2007) 164:708–10. doi: 10.1176/ajp.2007.164.5.708
58. Plano SA, Casiraghi LP, Garcia Moro P, Paladino N, Golombek DA, Chiesa JJ. Circadian and metabolic effects of light: implications in weight homeostasis and health. Front Neurol. (2017) 8:558. doi: 10.3389/fneur.2017.00558
59. Bainier C, Mateo M, Felder-Schmittbuhl M-P, Mendoza J. Circadian rhythms of hedonic drinking behavior in mice. Neuroscience. (2017) 349:229–38. doi: 10.1016/j.neuroscience.2017.03.002
60. Spector AC, Smith JC. A Detailed analysis of sucrose drinking in the rat. Physiol Behav. (1984) 33:127–36. doi: 10.1016/0031-9384(84)90023-4
61. Tõnissaar M, Herm L, Rinken A, Harro J. Individual differences in sucrose intake and preference in the rat: circadian variation and association with dopamine D2 receptor function in striatum and nucleus accumbens. Neurosci Lett. (2006) 403:119–24. doi: 10.1016/j.neulet.2006.04.023
62. Osnaya-Ramirez RI, Palma-Gomez M, Escobar C. Binge eating for sucrose is time of day dependent and independent of food restriction: effects on mesolimbic structures. Behav Neurosci. (2020) 134:267–81. doi: 10.1037/bne0000364
63. Nagai K, Nishio T, Nakagawa H, Nakamura S, Fukuda Y. Effect of bilateral lesions of the suprachiasmatic nuclei on the circadian rhythm of food-intake. Brain Res. (1978) 142:384–9. doi: 10.1016/0006-8993(78)90648-0
64. Van Den Pol AN, Powley T. A Fine-Grained anatomical analysis of the role of the rat suprachiasmatic nucleus in circadian rhythms of feeding and drinking. Brain Res. (1979) 160:307–26. doi: 10.1016/0006-8993(79)90427-X
65. Stephan FK, Zucker I. Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions. Proc Nat Acad Sci. (1972) 69:1583–6. doi: 10.1073/pnas.69.6.1583
66. Hampp G, Ripperger JA, Houben T, Schmutz I, Blex C, Perreau-Lenz S, et al. Regulation of monoamine oxidase a by circadian-clock components implies clock influence on mood. Current Biology. (2008) 18:678–83. doi: 10.1016/j.cub.2008.04.012
67. Hood S, Cassidy P, Cossette M-P, Weigl Y, Verwey M, Robinson B, et al. Endogenous dopamine regulates the rhythm of expression of the clock protein per2 in the rat dorsal striatum via daily activation of d2 dopamine receptors. J Neurosci. (2010) 30:14046–58. doi: 10.1523/JNEUROSCI.2128-10.2010
68. Luo AH, Aston-Jones G. Circuit projection from suprachiasmatic nucleus to ventral tegmental area: a novel circadian output pathway. Eur J Neurosci. (2009) 29:748–60. doi: 10.1111/j.1460-9568.2008.06606.x
69. Luo AH, Georges FE, Aston-Jones GS. Novel neurons in ventral tegmental area fire selectively during the active phase of the diurnal cycle. Eur J Neurosci. (2008) 27:408–22. doi: 10.1111/j.1460-9568.2007.05985.x
70. Kanerva N, Kronholm E, Partonen T, Ovaskainen M-L, Kaartinen NE, Konttinen H, et al. Tendency toward eveningness is associated with unhealthy dietary habits. Chronobiol Int. (2012) 29:920–7. doi: 10.3109/07420528.2012.699128
71. Maukonen M, Kanerva N, Partonen T, Kronholm E, Konttinen H, Wennman H, et al. The associations between chronotype, a healthy diet and obesity. Chronobiol Int. (2016) 33:972–81. doi: 10.1080/07420528.2016.1183022
72. Adan A. Chronotype and personality factors in the daily consumption of alcohol and psychostimulants. Addiction. (1994) 89:455–62. doi: 10.1111/j.1360-0443.1994.tb00926.x
73. Arora T, Taheri S. Associations among late chronotype, body mass index and dietary behaviors in young adolescents. Int J Obes. (2015) 39:39–44. doi: 10.1038/ijo.2014.157
74. Maukonen M, Kanerva N, Partonen T, Kronholm E, Tapanainen H, Kontto J, et al. Chronotype differences in timing of energy and macronutrient intakes: a population-based study in adults. Obesity. (2017) 25:608–15. doi: 10.1002/oby.21747
75. Mendoza J. Food intake and addictive-like eating behaviors: time to think about the circadian clock (S). Neurosci Biobehav Rev. (2019) 106:122–32. doi: 10.1016/j.neubiorev.2018.07.003
Keywords: binge-eating, circadian, sleep, chronotype, BED, NES
Citation: Plano SA, Soneira S, Tortello C and Golombek DA (2022) Is the binge-eating disorder a circadian disorder? Front. Nutr. 9:964491. doi: 10.3389/fnut.2022.964491
Received: 08 June 2022; Accepted: 04 July 2022;
Published: 22 July 2022.
Edited by:
Carolina Escobar, National Autonomous University of Mexico, MexicoReviewed by:
Estefania Espitia-Bautista, Universidad Nacional Autónoma de México, MexicoCopyright © 2022 Plano, Soneira, Tortello and Golombek. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Diego A. Golombek, dgolombek@gmail.com