This article is a correction to:
Genetically predicted lipids mediate the association between intrahepatic cholestasis of pregnancy and cardiovascular disease
Ji Cui1,†
Qilong Zhai
Zhu Yang- 1Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
- 2Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
A Corrigendum on
By Cui J, Zhai Q, Chen M, Yang Z. (2024). Front. Cardiovasc. Med. 11:1401010. doi: 10.3389/fcvm.2024.1401010
In the published article, there was an error in Figure 1 as published. The SNP screening threshold was incorrectly written as P < 1 × 10−8. The correct threshold is P < 5 × 10−8. The corrected Figure 1 and it's caption appears below.
Figure 1
Figure 1 (A) The basic assumptions of MR and (B) study design. SNP, single nucleotide polymorphisms; ICP, intrahepatic cholestasis of pregnancy; IVW, inverse variance weighted; WM, weighted median; CVD, cardiovascular disease; HTN, hypertension; CAD, coronary artery disease; GWAS, genome-wide association studies; IEU, integrative epidemiology unit open GWAS project.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
In the published article, there was an error. A prerequisite for the exclusion of outlier SNPs is missing before the description of the results of the sensitivity analyses.
A correction has been made to Results, 3.1 Causal effect between ICP and CVD (CAD, HTN) via TSMR. This sentence previously stated:
“The robustness of the results was assessed through Cochran's Q test, the MR-Egger intercept test and MR-PRESSO, as detailed in Supplementary Material Table S3.”
The corrected sentence appears below:
“After removing outlier SNP, the causal relationship between ICP and CVD still remained. The robustness of the results after removing outlier SNP was assessed through Cochran's Q test, the MR-Egger intercept test and MR-PRESSO, as detailed in Supplementary Material Table S3.”
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
In the published article, there was an error in Supplementary Table 3. The results of the sensitivity analyses in the original Supplementary Table 3 were incorrectly calculated due to incomplete data extraction and exclusion of outlier SNP values; the revised results are shown in the corrected Supplementary Table 3. The correct material statement appears below.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: intrahepatic cholestasis of pregnancy, lipid, cardiovascular disease, Mendelian randomization, GWAS
Citation: Cui J, Zhai Q, Chen M and Yang Z (2024) Corrigendum: Genetically predicted lipids mediate the association between intrahepatic cholestasis of pregnancy and cardiovascular disease. Front. Cardiovasc. Med. 11: 1439868. doi: 10.3389/fcvm.2024.1439868
Received: 28 May 2024; Accepted: 5 July 2024;
Published: 18 July 2024.
Edited and Reviewed by: Chieko Mineo, University of Texas Southwestern Medical Center, United States
© 2024 Cui, Zhai, Chen and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Mengjie Chen, chenmengjie@hospital.cqmu.edu.cn; Zhu Yang, yangzhu@hospital.cqmu.edu.cn
†These authors have contributed equally to this work and share first authorship