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Neurotransmitter release at a synapse

Neurotransmitter release at a synapse

A dissipative particle dynamics simulation of a 30 nm synaptic vesicle fusing to the pre-synaptic membrane and releasing 2000 glutamate molecules into the synaptic cleft. They diffuse across the cleft and can bind to receptors on the post-synaptic side. The synaptic membrane is 100 nm x 100 nm.