The following Research Topics are led by experts in their field and contribute to the scientific understanding of genetics. These Research topics are published in the peer-reviewed journal Frontiers in Genetics, as open access articles.
With the advent of next-generation technologies, a large number of genetic diseases have been characterized with the causative genes and gene modifiers. Different developmental anomalies arise as a result of genetic alterations in growth factor genes...
Mechanistic modeling is a powerful tool for elucidating and probing the behaviors of complex biological systems. By developing mathematical representations based on a deep understanding of biological mechanisms, mechanistic models can provide valuabl...
This research topic aims to provide an overview of the most recent advancements in understanding molecular mechanisms to develop biomarkers that can be selectively addressed to enhance the diagnosis, prognosis, and therapeutic interventions in gastro...
In the past decades, quickly evolving sequencing technology accompanied with big data in computational science has driven a lot of novel medical applications, especially enabling the discovery of associations and causalities. Genome-wide association ...
The introduction of next-generation sequencing (NGS) as well as long-read sequencing technologies has revolutionized the landscape. Over two decades, these technologies have provided high-throughput delivery of genomic data that is more affordable, e...
Our daily diet is more than a collection of carbohydrates, lipids and proteins, minerals and vitamins that provide energy and serve as building blocks of our life, it is also the most dominant environmental signal to which we are exposed from womb to...
Fresh fruits and vegetables are invaluable for human health and diet, but their quality deteriorates before reaching consumers due to ongoing processes related to ripening and senescence. The field of postharvest biology and technology addresses many...
Conservation genetics is a fundamental discipline for planning actions for the species and ecosystems management, conservation, and sustainable use. Initially, this work was carried out through collaborative efforts of research groups, sometimes from...
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects an estimated 50 million people worldwide. This disease is currently the most common cause of dementia in older adults.<br/><br/>Many people wonder if Alzheimer’s diseas...
Genomic analysis and related molecular analysis technologies undergo rapid advancements, in principle enabling the identification of any genetic alteration potentially implicated in the pathogenesis of diseases and conditions - for germline analyses ...