Last Interglacial | List of Frontiers open access articles

Original Research

Published on 01 Oct 2025

Targeting the CCL28-STAT3-PLAC8 axis to suppress metastasis and remodel tumor microenvironment in colorectal cancer

in Cancer Immunity and Immunotherapy

Yao Yang
Qixin Jiang
Zhe Zhu
Shun Zhang
Tao Du
Shuzheng Song
Xiaohua Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610540

113 views

Original Research

Published on 01 Oct 2025

Development and validation of a novel sodium-overload related genes signature for prognostic prediction in breast cancer: integrating bioinformatics and experimental approaches

in Cancer Immunity and Immunotherapy

Qizhen Feng
Wenlin Yang
Guohao Su
Fei Wu
Chungen Xing

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653903

246 views

Original Research

Published on 01 Oct 2025

A prospective analysis of lymph node retrieval in colorectal cancer: discrepancies, neoadjuvant impact, and practical implications

in Pathology

Saumik Biswas
Jesse R. Walsh
Sami Ul Haq
Ann M. Marilley
Elizabeth P. Pasman
Monica Kendall
Matthew Cecchini
Grace Lebbin
Darren Wilson

Frontiers in Medicine

doi 10.3389/fmed.2025.1611170

204 views

Original Research

Published on 01 Oct 2025

Computational simulations of endocrine bone diseases related to pathological glandular PTH secretion using a multi-scale bone cell population model

in Biomechanics

Corinna Modiz
Natalia M. Castoldi
Stefan Scheiner
Javier Martínez-Reina
Jose L. Calvo-Gallego
Vittorio Sansalone
Saulo Martelli
Peter Pivonka

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1619276

363 views

Original Research

Published on 01 Oct 2025

Pediatric Mycoplasma pneumoniae-induced rash and mucositis in China: clinical spectrum, co-infections and risk factors for recurrence—a retrospective cohort study

in Skin Allergy

Yang Wang
Lei Jiao
Lin Ma
Zigang Xu
Yuan Liang

Frontiers in Allergy

doi 10.3389/falgy.2025.1646688

354 views

Systematic Review

Published on 01 Oct 2025

Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis

in Climate and Health

Zewudu Andualem
Ayenew Takele Alemu
Azeb Geddif
Genet Gedamu Kassie
Kalkidan Worku Mitiku
Mahider Awoke Belay
Mulat Belay Simegn
Samuel Dagne Chanie
Werkneh Melkie Tilahun
Yonatan Menber

Frontiers in Climate

doi 10.3389/fclim.2025.1555383

349 views

Original Research

Published on 01 Oct 2025

Impact of an aerosolized or intramuscular adenovirus type 5-vectored COVID-19 vaccine on Fc-mediated immune effector functions in a hybrid immunity population

in Vaccines and Molecular Therapeutics

Mingzhi Gan
Weiwei Han
Chuang Li
Simin Li
Zhuangzhuang Huang
Lingjie Xu
Xiaoyu Xu
Xiangjun Zhai
Yuxin Chen
Jingxin Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657235

379 views

Original Research

Published on 01 Oct 2025

Mongolian medicine theory-based multidimensional evaluation of toxicity mitigation in Hezi-processed Caowu jointly mediated by powder dosage form and small dose

in Ethnopharmacology

Jing Wang
Liyuan Bao
Ying Zhao
Liangliang Song
Wenting Zu
Jiasheng Wang
Hongshuang Chi
Yichen Li
Hong Du

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1679105

460 views

Original Research

Published on 01 Oct 2025

Characterization of human skeletal stem cells in closed and open tibia fractures: a single center pilot study

in Skeletal Physiology

Rubén Tresgallo-Parés
David Morales
Shannon Tse
Aziz Saade
Ellen Fitzpatrick
Sean T. Campbell
Gillian L. Soles
Thomas H. Ambrosi
Mark A. Lee
Augustine M. Saiz

Frontiers in Physiology

doi 10.3389/fphys.2025.1638064

1,619 views

Original Research

Published on 01 Oct 2025

Pharmacoeconomic evaluation of ICS-LABA therapy in pediatric asthma: a cost-effectiveness and cost-utility analysis

in Obstetric and Pediatric Pharmacology

Fan Dai
Jin Xu
Jing Xu
Wenjing Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1639444

1,594 views

Original Research

Published on 01 Oct 2025

IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis

in Cytokines and Soluble Mediators in Immunity

Jiezhong Deng
Jun Gu
Xiaoshan Gong
Hao Tang
Yuyi Cai
Yusheng Yang
Shiwu Dong
Chunrong Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630253

1,085 views

Case Report

Published on 01 Oct 2025

“Spider Web”-like zonular deposits in pseudoexfoliation syndrome: endoscopic insights—a case report

in Ophthalmology

Bin Lin
Ling Zhang
Dong-kan Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1589973

234 views

Review

Published on 01 Oct 2025

From stress signals to fertility challenges: the role of damage-associated molecular patterns in male reproduction

in Molecular Innate Immunity

Heran Cao
Shujuan Liu
Shichao Cui
Hua Nie
Xiaohua Liu
Weibing Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598451

985 views

Perspective

Published on 01 Oct 2025

Environmental sustainability, an essential outcome for implementation scientists to improve health

in Implementation Science

Virginia Mckay
Emmanuel Tetteh
Nicholas Wong
C. Bradley Kramer
Jason Burnham

Frontiers in Health Services

doi 10.3389/frhs.2025.1664446

279 views

Systematic Review

Published on 01 Oct 2025

Risk factors for postherpetic neuralgia: a meta-analysis based on demographic, clinical features, and treatment characteristics

in Viral Immunology

Jing Wang
Rong Tao
Yinghai Jiang
Zhuoya Ma
Lingjie Xia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667364

178 views

Original Research

Published on 01 Oct 2025

Host S100A6 inhibits ZIKV replication by degrading NS3 through lysosomal pathway

in Virus and Host

Jiao Peng
WeiHao Zou
Lijuan Zhou
Runchun Liu
Hong-Juan Peng

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1602743

351 views

Articles

Targeting the CCL28-STAT3-PLAC8 axis to suppress metastasis and remodel tumor microenvironment in colorectal cancer

Development and validation of a novel sodium-overload related genes signature for prognostic prediction in breast cancer: integrating bioinformatics and experimental approaches

A prospective analysis of lymph node retrieval in colorectal cancer: discrepancies, neoadjuvant impact, and practical implications

Computational simulations of endocrine bone diseases related to pathological glandular PTH secretion using a multi-scale bone cell population model

Pediatric Mycoplasma pneumoniae-induced rash and mucositis in China: clinical spectrum, co-infections and risk factors for recurrence—a retrospective cohort study

Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis

Impact of an aerosolized or intramuscular adenovirus type 5-vectored COVID-19 vaccine on Fc-mediated immune effector functions in a hybrid immunity population

Mongolian medicine theory-based multidimensional evaluation of toxicity mitigation in Hezi-processed Caowu jointly mediated by powder dosage form and small dose

Characterization of human skeletal stem cells in closed and open tibia fractures: a single center pilot study

Pharmacoeconomic evaluation of ICS-LABA therapy in pediatric asthma: a cost-effectiveness and cost-utility analysis

IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis

“Spider Web”-like zonular deposits in pseudoexfoliation syndrome: endoscopic insights—a case report

From stress signals to fertility challenges: the role of damage-associated molecular patterns in male reproduction

Environmental sustainability, an essential outcome for implementation scientists to improve health

Risk factors for postherpetic neuralgia: a meta-analysis based on demographic, clinical features, and treatment characteristics

Host S100A6 inhibits ZIKV replication by degrading NS3 through lysosomal pathway