Epidemiological evidence shows that lifestyle factors such as poor diet, obesity, and inactivity, play an important role in determining rates of incidence, recurrence, and prognosis of many types of cancer. Leisure-time physical activity is associated with lower risks of several types of cancer, supporting the promotion of physical activity as a key component of population-wide cancer prevention and control efforts. Particularly, postdiagnosis physical exercise is strongly associated with increased survival of cancer patients, especially breast, colorectal, and prostate cancer survivors, making exercise oncology a growing and attractive research field. In front of the available epidemiological body of evidence, there is a need for exercise intervention trials showing modes of action and further defining the exercise prescription, biological mechanisms, and possible risks.
This opens to the development of new approaches in the methodologies for cancer progression control, such as in vivo models and/or the use of exercise-conditioned human serum in cell culture models. These translational approaches offer the opportunity to identify key anti-oncogenic protein targets and optimize physical activity recommendations and intervention protocols for cancer tertiary prevention, treatment, and survivorship. Articles from this collection will offer the opportunity to advance the knowledge about exercise physiology and cancer biology, improving our understanding of the relationship between physical exercise and cancer, with the aim to optimize recommendations for cancer prevention, treatment, and survivorship and identify novel therapeutic targets.
The aim of this Research Topic is to provide a platform for original research and review articles describing the advances in exercise oncology through intervention trials and translational approaches. We encourage the contribution of articles involving all aspects of translation research, such as cellular and animal models, the analysis of exercise-induced circulating molecules as well as their biological activity on cancer cells. Research articles regarding clinical trials on supervised physical exercise in cancer survivors describing the effects of different exercise types and intensities on quality of life, physiologic amelioration, and psychological impact are welcome. Articles describing the impact of physical activity and lifestyle changes on cancer prevention are welcome as well.
The topic supports #SDG3 Good Health and Well Being
Epidemiological evidence shows that lifestyle factors such as poor diet, obesity, and inactivity, play an important role in determining rates of incidence, recurrence, and prognosis of many types of cancer. Leisure-time physical activity is associated with lower risks of several types of cancer, supporting the promotion of physical activity as a key component of population-wide cancer prevention and control efforts. Particularly, postdiagnosis physical exercise is strongly associated with increased survival of cancer patients, especially breast, colorectal, and prostate cancer survivors, making exercise oncology a growing and attractive research field. In front of the available epidemiological body of evidence, there is a need for exercise intervention trials showing modes of action and further defining the exercise prescription, biological mechanisms, and possible risks.
This opens to the development of new approaches in the methodologies for cancer progression control, such as in vivo models and/or the use of exercise-conditioned human serum in cell culture models. These translational approaches offer the opportunity to identify key anti-oncogenic protein targets and optimize physical activity recommendations and intervention protocols for cancer tertiary prevention, treatment, and survivorship. Articles from this collection will offer the opportunity to advance the knowledge about exercise physiology and cancer biology, improving our understanding of the relationship between physical exercise and cancer, with the aim to optimize recommendations for cancer prevention, treatment, and survivorship and identify novel therapeutic targets.
The aim of this Research Topic is to provide a platform for original research and review articles describing the advances in exercise oncology through intervention trials and translational approaches. We encourage the contribution of articles involving all aspects of translation research, such as cellular and animal models, the analysis of exercise-induced circulating molecules as well as their biological activity on cancer cells. Research articles regarding clinical trials on supervised physical exercise in cancer survivors describing the effects of different exercise types and intensities on quality of life, physiologic amelioration, and psychological impact are welcome. Articles describing the impact of physical activity and lifestyle changes on cancer prevention are welcome as well.
The topic supports #SDG3 Good Health and Well Being