About this Research Topic

Background

Management of and Rehabilitation from cardiovascular diseases (CVD) in recent decades is one of the greatest tasks for health professionals. Besides the therapeutic problem, it is well known that the prevention of a possible ischemic event can be an important factor in reducing the consequences of this disease both in terms of the clinical picture and in terms of treatment costs. Numerous studies published in the last decade support the statement of regular physical exercise being effective and long term cardioprotective maneuver. On the other hand, there is still a debate about the fact that exercising regularly reduces a great number of cardiovascular risk factors like hypertension, obesity, diabetes mellitus and many others.

Although regular physical activity has been proven to reduce CVD associated morbidity and mortality, optimal duration, frequency, and intensity of it remains unclear. While the exact mechanisms are not yet fully known, some studies have made it clear that both total energy expenditure during exercise and exercise intensity play a significant role in preventing myocardial infarction. Considering all that, new training protocols were developed and were tested in recent years, throwing a new light on what was previously thought to be just a healthy habit.

In the last decade, the development of new non-pharmacological principles of myocardial preconditioning has become one of the important tasks in this research field. Compared to other non-pharmacological types of preconditioning, physical activity has proven to be potentially the most effective with several promising results in this field. Although specific protective mechanisms of exercise preconditioning have not been identified so far, it is assumed that they include an increase in myocardial enzymatic antioxidant activity and more successful neutralization of reactive oxygen species, especially during the reperfusion period.



In the last two decades, there has been a significant rise in a plethora of data regarding cardioprotective impact of physical activity. It would be of great interest to know which undelaying mechanism placing physical activity as a potential partner in recovery form mild and severe CV events both in experimental and clinical studies and moreover how physical activity can affect CVD as preventive but also as postconditioning maneuver.

The topic supports #SDG3 Good Health and Well Being

Keywords: Cardiovascular, Exercise, CVD, Health

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