Computational Modeling of Various Procedures in Thermal Therapy of Human Tumors

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About this Research Topic

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Background

Cancers have been recognized as a leading cause of premature death worldwide. The traditional treatment methods, i.e., radiotherapy, chemotherapy, and surgery, all suffer from different kinds of side effects and limitations. Due to its minimal- or non-invasive nature and being free of side effects, thermal therapy has become a very promising alternative treatment for benign tumors.

Currently, different types of thermal therapy have been proposed including photothermal therapy, ultrasound thermal therapy, radiofrequency thermal therapy, magnetic hyperthermia, etc. The most important issue to address in thermal therapy is the temperature control. Precise numerical modeling of the bioheat transfer process and other related procedures is one of the most important ways to provide guidance for the temperature monitoring and control during thermal therapy, and also for the therapeutic schedule design before thermal therapy begins.

The aim of this Research Topic is to cover the most recent achievements in the field of computational modeling of various procedures in the thermal therapy of human tumors, including heat transfer, light transfer, blood flow, thermal damage, etc. All of which are extremely important to the providing of guidance for the clinical applications.

Accurate numerical models to describe the above-mentioned procedures are the most important step for the successful implementation of thermal therapy. On this basis, different strategies can be proposed, examined, and optimized to reach the desired therapeutic effect. In addition, the development of numerical methods for the fast and high-resolution estimation of 3D temperature field in biological tissue during thermal therapy is also of extreme importance and waiting to be investigated.

Areas to be covered in this Research Topic include, but are not limited to:

• Bioheat transfer modeling in thermal therapy
• New strategies for tumor heating
• Nanoparticle assisted thermal therapy
• Thermophysical properties of nanoparticles
• Temperature measurement and monitoring during thermal therapy
• Microwave ablation, radiofrequency ablation, photothermal therapy, high-intensity focused ultrasound ablation

All article types are welcome in this Research Topic, with the following being of particular interest: original research, review, mini review, and perspective.

Keywords: thermal therapy, bioheat transfer, nanoscale heat conversion, numerical methods, minimally invasive treatment, heating strategy

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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