Biology of NK cells and NK cell receptors

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INSERM U1104 Centre d'immunologie de Marseille-Luminy (CIML)

Hans-Gustaf Ljunggren

Karolinska Institutet (KI)

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Natural Killer (NK) cells are lymphocytes which can be cytotoxic and secrete cytokines. NK cells recognize cells in distress, such as upon microbial infection, tumor transformation, physical or chemical assaults. NK cells participate to the innate immune responses as effector cells, and also contribute to the shaping on adaptive immune responses.

The manipulation of the anti-tumor function of NK cells has raised considerable interest among clinicians. This research topic will highlight the recent advances in NK cell research in human and mouse, at the molecular and organismal scales, from basic research to clinical applications.

Natural Killer (NK) cells are lymphocytes which can be cytotoxic and secrete cytokines. NK cells recognize cells in distress, such as upon microbial infection, tumor transformation, physical or chemical assaults. NK cells participate to the innate immune responses as effector cells, and also contribute to the shaping on adaptive immune responses.

The manipulation of the anti-tumor function of NK cells has raised considerable interest among clinicians. This research topic will highlight the recent advances in NK cell research in human and mouse, at the molecular and organismal scales, from basic research to clinical applications.

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Editors

INSERM U1104 Centre d'immunologie de Marseille-Luminy (CIML)

Hans-Gustaf Ljunggren

Karolinska Institutet (KI)

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Frontiers in Immunology

NK and Innate Lymphoid Cell Biology

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