Neuroimaging Approaches to the Study of Tinnitus and Hyperacusis

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Editorial

14 July 2021

Editorial: Neuroimaging Approaches to the Study of Tinnitus and Hyperacusis

Qian Chen

,

Han Lv

,

Yu-Chen Chen

,

Jae-Jin Song

and

Zhenchang Wang

5,746 views

6 citations

Editors

3

Beijing Friendship Hospital, Capital Medical University

Seoul National University Bundang Hospital

Department of Radiology, Nanjing First Hospital, Nanjing Medical University

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Approximately 12% of adults experience tinnitus, but about 1% experience severe tinnitus that is in some cases disabling. Tinnitus is often accompanied by hyperacusis, a debilitating condition in which moderate intensity sounds are perceived as extremely loud. Tinnitus and hyperacusis were originally thought to originate in the cochlea as a consequence of hearing loss; however, over the past two decades, there has been a growing recognition that tinnitus and hyperacusis originate from aberrant neuroplastic changes in the central nervous system caused or triggered by cochlear hearing loss.

Recent brain imaging studies using multichannel quantitative EEG, positron emission tomography (PET) and functional MRI have revealed a plethora of functional and structural changes in the central nervous system associated with tinnitus and hyperacusis. From these studies, a number of key concepts have emerged linking tinnitus and/or hyperacusis to enhanced central gain, altered functional connectivity in neural network, aberrant rhythmic activity in cortical networks, spontaneous hyperactivity, and aberrant activity in regions of the brain associated with anxiety, attention, emotion, and memory.

In this Research Topic, we invite some of the world’s leading brain imaging experts to produce a series of state of the art reviews and groundbreaking research dealing with tinnitus and hyperacusis in humans and animal models.

Approximately 12% of adults experience tinnitus, but about 1% experience severe tinnitus that is in some cases disabling. Tinnitus is often accompanied by hyperacusis, a debilitating condition in which moderate intensity sounds are perceived as extremely loud. Tinnitus and hyperacusis were originally thought to originate in the cochlea as a consequence of hearing loss; however, over the past two decades, there has been a growing recognition that tinnitus and hyperacusis originate from aberrant neuroplastic changes in the central nervous system caused or triggered by cochlear hearing loss.

Recent brain imaging studies using multichannel quantitative EEG, positron emission tomography (PET) and functional MRI have revealed a plethora of functional and structural changes in the central nervous system associated with tinnitus and hyperacusis. From these studies, a number of key concepts have emerged linking tinnitus and/or hyperacusis to enhanced central gain, altered functional connectivity in neural network, aberrant rhythmic activity in cortical networks, spontaneous hyperactivity, and aberrant activity in regions of the brain associated with anxiety, attention, emotion, and memory.

In this Research Topic, we invite some of the world’s leading brain imaging experts to produce a series of state of the art reviews and groundbreaking research dealing with tinnitus and hyperacusis in humans and animal models.

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Editors

Beijing Friendship Hospital, Capital Medical University

Seoul National University Bundang Hospital

Department of Radiology, Nanjing First Hospital, Nanjing Medical University

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Frontiers in Neuroscience

Auditory Cognitive Neuroscience

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Frontiers in Psychology

Auditory Cognitive Neuroscience

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