About this Research Topic
The adaptive significance of developmental plasticity is dependent on numerous factors including, species, age, gender and the type of environmental stress. For mammals, which normally develop under relatively stable conditions, fluctuations in the developmental environment often produce pathological phenotypes which predispose an individual to disease. On the other hand, embryonic ectothermic vertebrates are routinely exposed to wide fluctuations in abiotic factors, such as temperature, pH and oxygen. For these organisms, developmental plasticity may provide a mechanism to develop useful adaptations to the environment. Therefore, conditions experienced during early life can “program” both health and disease in vertebrates.
Given that developmental plasticity is widespread phylogenetically, developmental programing has far-reaching implications for a variety of scientific disciplines, including ecology, evolution, conservation, medicine, public health and sociology. In this Research Topic, we aim to consolidate recent findings and identify common or novel phenotypic signatures associated with developmental programming. We welcome papers which explore the impact of environmental stressors (e.g. temperature, pH, nutrition, oxygen) on the physiology of a broad range of vertebrates (endothermic and ectothermic) across numerous life stages (embryonic, fetal, juvenile and adult) and levels of biological organization. The overall aim of the Research Topic is to provide a platform for an integrative and comparative discussion on the phenotypic consequences of developmental plasticity on vertebrate health and disease
Keywords: Developmental, programing, vertebrate, hypoxia, plasticity
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