Novel approaches to vaccine development

115.2K

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46

authors

10

articles

Novel approaches to vaccine development

115.2K

views

46

authors

10

articles

Editors

1

School of Medicine, Tulane University

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Traditional vaccination strategies, utilizing inactivated viral, bacterial, and toxoid preparations or live-attenuated strains, have successfully controlled diseases such as tetanus and polio. Safer formulations composed of purified polysaccharides or recombinant proteins yielded effective vaccines against pathogens such as Streptococcus pneumoniae and Hepatitis B virus. Nonetheless, the large majority of pathogens causing significant human morbidity and mortality across the globe, such as Mycobacterium tuberculosis, HIV, and Plasmodium falciparum, have evaded eradication by modern vaccine approaches. Newer vaccine technologies are urgently needed to combat these and other emerging infectious organisms. This research topic welcomes original research or review articles addressing innovative vaccine development against human pathogens. Areas of interest include but are not limited to: novel adjuvants; nanotechnology; delivery systems; alternative delivery routes (i.e. transcutaneous, intradermal); and vaccine manufacturing. Vaccine strategies utilizing a multi-antigen expression platform are of particular interest.

Traditional vaccination strategies, utilizing inactivated viral, bacterial, and toxoid preparations or live-attenuated strains, have successfully controlled diseases such as tetanus and polio. Safer formulations composed of purified polysaccharides or recombinant proteins yielded effective vaccines against pathogens such as Streptococcus pneumoniae and Hepatitis B virus. Nonetheless, the large majority of pathogens causing significant human morbidity and mortality across the globe, such as Mycobacterium tuberculosis, HIV, and Plasmodium falciparum, have evaded eradication by modern vaccine approaches. Newer vaccine technologies are urgently needed to combat these and other emerging infectious organisms. This research topic welcomes original research or review articles addressing innovative vaccine development against human pathogens. Areas of interest include but are not limited to: novel adjuvants; nanotechnology; delivery systems; alternative delivery routes (i.e. transcutaneous, intradermal); and vaccine manufacturing. Vaccine strategies utilizing a multi-antigen expression platform are of particular interest.

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Editors

School of Medicine, Tulane University

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Frontiers in Cellular and Infection Microbiology

Clinical Microbiology, Bacteria and Host, Virus and Host, Parasite and Host, Cellular and Infection Microbiology Archive, Viral Pathogenesis and Evolution

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