About this Research Topic
This Research Topic is part of The Molecular Mechanism of the Toxicity and Metabolism of Mycotoxins series: Contribution of the gut microbiome to the metabolism and detoxification of mycotoxins
Mycotoxins are secondary metabolites produced by many microfungi, including Alternaria, Aspergillus, Claviceps, Fusarium, Penicillium, etc. The contamination of mycotoxins to cereals and feedstuffs are inevitable, especially in wet weather, which causes enormous economic lost to food and feed industry every year worldwide. Mycotoxins can exert acute, sub-acute and chronic toxicological effects to animals and humans. On the cellular level, mycotoxins and their metabolites can elicit different kinds of disorders and adverse effects, such as oxidative stress, ribotoxic stress, DNA damage and apoptosis. Some enzymes and bacteria are implicated in the biotransformation of mycotoxins. However, the molecular mechanism of the toxicity and metabolism of many mycotoxins are unclear.
The aim of this Research Topic is to assemble review and original research articles on the molecular mechanisms of the toxicity and metabolism of mycotoxins, including aflatoxins, Fusarium toxins, Penicillium toxins etc.
Suggested topics:
1. The molecular mechanism of the toxicity of mycotoxins.
2. The metabolic enzymes of mycotoxins.
3. The microbes involved in mycotoxin detoxification.
Mycotoxins are secondary metabolites produced by many microfungi, including Alternaria, Aspergillus, Claviceps, Fusarium, Penicillium, etc. The contamination of mycotoxins to cereals and feedstuffs are inevitable, especially in wet weather, which causes enormous economic lost to food and feed industry every year worldwide. Mycotoxins can exert acute, sub-acute and chronic toxicological effects to animals and humans. On the cellular level, mycotoxins and their metabolites can elicit different kinds of disorders and adverse effects, such as oxidative stress, ribotoxic stress, DNA damage and apoptosis. Some enzymes and bacteria are implicated in the biotransformation of mycotoxins. However, the molecular mechanism of the toxicity and metabolism of many mycotoxins are unclear.
The aim of this Research Topic is to assemble review and original research articles on the molecular mechanisms of the toxicity and metabolism of mycotoxins, including aflatoxins, Fusarium toxins, Penicillium toxins etc.
Suggested topics:
1. The molecular mechanism of the toxicity of mycotoxins.
2. The metabolic enzymes of mycotoxins.
3. The microbes involved in mycotoxin detoxification.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
